CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFCD453
Family Name Sigma non-opioid intracellular receptor 1 Ligand MS-377 Family
No. of Seeds 1 No. of Other Members 21
Family Centroid CFAMM00158439 Functional Category Clinical Trial Drug
Superfamily Sigma non-opioid intracellular receptor 1 Ligand MS-377 Superfamily
Class Class 1110

Cousin Family NamesSeedsMembers
Dopamine receptor Ligand Domperidone Family 2 21
5-hydroxytryptamine receptor 1B and 5-hydroxytryptamine recept... 2 23
Tumor necrosis factor Inhibitor Pirfenidone Family 2 38
Gamma-aminobutyric acid A receptor Ligand ELB-139 Family 1 3
Serine/threonine-protein kinase mTOR Inhibitor CC-223 Family 12 135
Bifunctional epoxide hydrolase 2 Inhibitor 1-(3-chloro-phenyl)... 5 50
5-hydroxytryptamine receptor 1A and 5-hydroxytryptamine recept... 3 34
Bifunctional epoxide hydrolase 2 Inhibitor 1-phenyl-3-(1-propi... 22 183
5-hydroxytryptamine receptor 1A and 5-hydroxytryptamine recept... 53 289
D(2) dopamine receptor and D(3) dopamine receptor ligand AGN-P... 4 18
D(4) dopamine receptor and D(2) dopamine receptor ligand 2-[4-... 1 0
D(2) dopamine receptor and D(3) dopamine receptor ligand AGN-P... 5 5
D(4) dopamine receptor and Alpha-1B adrenergic receptor ligand... 7 27
D(3) dopamine receptor and D(2) dopamine receptor ligand 1-(3-... 6 12
5-hydroxytryptamine receptor 3A and 5-hydroxytryptamine recept... 3 1
Survival motor neuron protein and Retinal dehydrogenase 1 inhi... 1 1
C-C chemokine receptor type 1 ligand SureCN3159355 family 7 9
P2X purinoceptor 7 inhibitor SureCN3726471 family 3 0
P2X purinoceptor 7 inhibitor AGN-PC-088GOO family 3 0
P2X purinoceptor 7 inhibitor SureCN3721807 family 3 0
Dipeptidyl peptidase 4 inhibitor [(2S,4S)-4-[4-(4-chlorophenyl... 3 3
C-C chemokine receptor type 1 ligand N-[(2R)-1-[4-(4-chlorophe... 2 3
Kappa-type opioid receptor ligand AGN-PC-077Q4Y family 5 9
Kappa-type opioid receptor and Urotensin-2 receptor ligand 2-(... 5 1
Alpha-1B adrenergic receptor and Alpha-1D adrenergic receptor ... 2 1
Alpha-1D adrenergic receptor and Alpha-1B adrenergic receptor ... 14 0
Alpha-1D adrenergic receptor and Alpha-1B adrenergic receptor ... 3 1
Alpha-1D adrenergic receptor and Alpha-1B adrenergic receptor ... 2 0
Potassium voltage-gated channel subfamily H member 2 and D(3) ... 3 0
D(3) dopamine receptor and D(2) dopamine receptor ligand 1-(3-... 2 1
Survival motor neuron protein and Beta-lactamase inhibitor 3-C... 1 5


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00158439 DCL000888 Clinical Trial Drug MS-377

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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