CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

Family Name D(2) dopamine receptor Ligand N-0923 Family
No. of Seeds 6 No. of Other Members 41
Family Centroid CFAMM00158481 Functional Category Clinical Trial Drug with Human Metabolite
Superfamily D(2) dopamine receptor Ligand N-0923 Superfamily
Class Class 1111

Cousin Family NamesSeedsMembers
Beta adrenergic receptor ligand catecholamine group Isoprotere... 7 130
Opioid receptor ligand opiate Levorphanol Family 18 537
D(1B) dopamine receptor Ligand Apomorphine Family 30 271
Muscarinic acetylcholine receptor M3 Ligand Tolterodine Family 8 171
Noradrenergic re-uptake and Serotonin re-uptake Inhibitor Dulo... 8 6
Kappa-type opioid receptor Ligand Dezocine Family 36 46
Eptazocine Hbr family 6 8
5-hydroxytryptamine receptor 1A Ligand (s)-uh-301 Family 35 20
Delta-type opioid receptor and Kappa-type opioid receptor Liga... 5 27
D(2) dopamine receptor and D(1A) dopamine receptor Ligand SK&F... 8 8
DNA-(apurinic or apyrimidinic site) lyase and Menin inhibitor ... 1 6
D(2) dopamine receptor and D(1A) dopamine receptor ligand (6aR... 2 4
Mu-type opioid receptor and Kappa-type opioid receptor ligand ... 2 0
D(1A) dopamine receptor and D(1) dopamine receptor ligand Sure... 1 0
Mu-type opioid receptor and Kappa-type opioid receptor ligand ... 3 0
Mu-type opioid receptor and Kappa-type opioid receptor ligand ... 2 1
Glutamate receptor ionotropic, NMDA 2B and Glutamate receptor ... 1 1


External ID

Functional Category

Molecule Name

CFAMM00158474 CHEMBL330138 Bioactive 3-[(3R,4R)-3,4-dimethyl-1-(2-thiophen-2-ylethyl)piperidin-4-yl]phenol
CFAMM00158487 CHEMBL7806 Bioactive N 0734
CFAMM00158493 CHEMBL135954 Bioactive 2-Naphthalenol, 5,6,7,8-tetrahydro-7-[propyl[2-(2-thienyl)ethyl]amino]-
CFAMM00158458 CHEMBL155613 Bioactive (6S)-6-[propyl(2-thiophen-2-ylethyl)amino]-5,6,7,8-tetrahydronaphthalene-1,2-diol
CFAMM00158481 DCL000889 Clinical Trial Drug N-0923
CFAMM00158488 DNC001233 Investigative Drug Rotigitine

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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