CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

Family Name D(2) dopamine receptor and D(3) dopamine receptor Ligand PD-157695 Family
No. of Seeds 2 No. of Other Members 9
Family Centroid CFAMM00158856 Functional Category Clinical Trial Drug
Superfamily D(2) dopamine receptor and D(3) dopamine receptor Ligand PD-157695 Superfamily
Class Class 1117

Cousin Family NamesSeedsMembers
Transforming growth factor-beta Inhibitor ACE-011 Family 1 13
C-X-C chemokine receptor type 2 Ligand 1-(5-chloro-2-hydroxy-4... 1 3
Carbonic anhydrase 1 and Carbonic anhydrase 2 inhibitor 1-(2,5... 1 1
Tyrosyl-DNA phosphodiesterase 1 and Transient receptor potenti... 1 0


External ID

Functional Category

Molecule Name

CFAMM00158856 DCL000917 Clinical Trial Drug PD-157695
CFAMM00158858 DNC003855 Investigative Drug 1-(2-Hydroxy-4-nitro-phenyl)-3-phenyl-urea

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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