CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFCD471
Family Name 5-hydroxytryptamine receptor 1A and Sigma non-opioid intracellular receptor 1 Ligand PRX-00023 Family
No. of Seeds 7 No. of Other Members 28
Family Centroid CFAMM00159569 Functional Category Clinical Trial Drug with Natural Product
Superfamily 5-hydroxytryptamine receptor 1A and Sigma non-opioid intracellular receptor 1 Ligand PRX-00023 Superfamily
Class Class 1122

Cousin Family NamesSeedsMembers
Mu-type opioid receptor Ligand Fentanyl Family 9 647
Mannose-6-phosphate isomerase Inhibitor Sulfacetamide Family 19 117
Carbonic anhydrase 1 and Carbonic anhydrase 2 Inhibitor N-(4-s... 12 92
Potassium voltage-gated channel subfamily A member 5 Ligand N-... 8 32
Carbonic anhydrase 1 and Carbonic anhydrase 2 Inhibitor 2-morp... 6 81
Carbonic anhydrase 1 and Carbonic anhydrase 2 Inhibitor 4-[2-(... 5 72
5-hydroxytryptamine receptor 6 Ligand 4-(4-benzenesulfonamidop... 4 5
5-hydroxytryptamine receptor 6 Ligand N-(3-(2-aminoethyl)pheny... 8 25
Delta-type opioid receptor and Mu-type opioid receptor Ligand ... 14 110
D(2) dopamine receptor Ligand 1-benzyl-4-[3-(methylsulfonyl)ph... 2 7
Bifunctional epoxide hydrolase 2 Inhibitor 1-phenyl-3-(1-propi... 22 183
5-hydroxytryptamine receptor 1A and 5-hydroxytryptamine recept... 6 45
5-hydroxytryptamine receptor 1A and 5-hydroxytryptamine recept... 3 31
Acetylcholinesterase Inhibitor (3-hydroxy-2-methyl-phenyl)-tri... 4 25
Bifunctional epoxide hydrolase 2 inhibitor AGN-PC-04TGG7 family 2 3
Neutrophil elastase inhibitor SureCN7448165 family 2 4
Carbonic anhydrase 2 and Carbonic anhydrase 1 inhibitor 2-amin... 2 2
5-hydroxytryptamine receptor 6 and 5-hydroxytryptamine recepto... 9 26
Cannabinoid receptor 2 ligand 4-methyl-3-piperidin-1-ylsulfony... 2 0
Carbonic anhydrase 9 and Carbonic anhydrase 2 inhibitor AGN-PC... 6 2
B1 bradykinin receptor ligand N-[(1R)-6-[(dimethylamino)methyl... 7 6
B1 bradykinin receptor ligand N-[(4S)-1-ethyl-3,3-dimethylpipe... 10 4
Protein-glutamine gamma-glutamyltransferase 2 and Coagulation ... 1 0
Bifunctional epoxide hydrolase 2 inhibitor 1-(2,4-dimethylphen... 4 8
Cannabinoid receptor 2 and Cannabinoid receptor 1 ligand N-[[4... 7 11
Carbonic anhydrase 12 and Carbonic anhydrase 9 inhibitor (E)-2... 2 0
Disintegrin and metalloproteinase domain-containing protein 17... 7 5
Collagenase 3 and Neutrophil collagenase inhibitor (2R)-2-[ben... 2 12
Growth hormone secretagogue receptor type 1 ligand SureCN47963... 3 3
Growth hormone secretagogue receptor type 1 ligand SureCN48016... 5 4
Dipeptidyl peptidase 4 inhibitor 4-[4-[(3S,5S)-5-(1,3-thiazoli... 3 2
D(3) dopamine receptor and D(2) dopamine receptor ligand 4-met... 2 0
Neuropeptide Y receptor type 5 ligand 3-[1-(3,5-difluorophenyl... 4 0
Matrix metalloproteinase-9 and Neutrophil collagenase inhibito... 7 0
5-hydroxytryptamine receptor 2C and 5-hydroxytryptamine recept... 3 2
Orexin receptor type 2 ligand SureCN1039013 family 1 0
Corticosteroid 11-beta-dehydrogenase isozyme 1 inhibitor KB-74... 2 0
Corticosteroid 11-beta-dehydrogenase isozyme 1 inhibitor SureC... 2 0
Prothrombin and Proteinase-activated receptor 1 ligand (2S)-N-... 2 4
5-hydroxytryptamine receptor 2A and 5-hydroxytryptamine recept... 1 0
Carbonic anhydrase and Carbonic anhydrase 2 inhibitor AGN-PC-0... 2 0
Protein-glutamine gamma-glutamyltransferase 2 and Coagulation ... 3 2
Coagulation factor XIII A chain and Protein-glutamine gamma-gl... 2 3
Chymase and Chymotrypsinogen A inhibitor SureCN7836048 family 2 0
Carbonic anhydrase 9 and Carbonic anhydrase 2 inhibitor AGN-PC... 1 1


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00159551 CHEMBL377697 Bioactive SureCN1383630
CFAMM00159547 CHEMBL210537 Bioactive SureCN3869342
CFAMM00159544 CHEMBL379984 Bioactive AGN-PC-08VZGI
CFAMM00159534 CHEMBL207220 Bioactive AGN-PC-00AQFQ
CFAMM00159516 CHEMBL207478 Bioactive AGN-PC-08XUYW
CFAMM00159543 CHEMBL211012 Bioactive SureCN1384812
CFAMM00159569 DCL000937 Clinical Trial Drug PRX-00023

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

27419 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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