CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFCD474
Family Name Substance-P receptor Ligand R 673 Family
No. of Seeds 2 No. of Other Members 127
Family Centroid CFAMM00159671 Functional Category Clinical Trial Drug with Human Metabolite & Natural Product
Superfamily Substance-P receptor Ligand R 673 Superfamily
Class Class 994

Cousin Family NamesSeedsMembers
Cyclooxygenase Inhibitor Oxaprozin Family 33 450
Nitric oxide synthase, endothelial Inhibitor Acclaim Family 2 15
Acetyl-CoA acetyltransferase, mitochondrial Inhibitor Benoxapr... 1 76
FX005 family 2 1
C-C chemokine receptor type 2 and C-C motif chemokine 2 Ligand... 3 52
Peroxisome proliferator-activated receptor gamma and Peroxisom... 15 94
Chymase Inhibitor Y-40613 Family 11 56
Melatonin receptor type 1B Ligand N-(3-benzooxazol-7-yl-propyl... 26 101
Fatty-acid amide hydrolase 1 Inhibitor (z)-1-(benzo[d]oxazol-2... 2 27
Fatty-acid amide hydrolase 1 Inhibitor 1-(oxazolo[4,5-b]pyridi... 19 34
Fatty-acid amide hydrolase 1 Inhibitor 1-(5-(pyridin-2-yl)oxaz... 10 142
Oestrogen receptor and Estrogen receptor beta Ligand 2-naphtha... 4 51
Oestrogen receptor and Estrogen receptor beta Ligand 2-(6-hydr... 9 22
Prostacyclin receptor and Prostaglandin E2 receptor EP3 subtyp... 4 17
Neutrophil elastase Inhibitor Cbz-val-pro-val-(2-benzoxazole) ... 32 64
Leukotriene A-4 hydrolase Inhibitor 2-[4-(2-azepan-1-ylethoxy)... 5 15
Peroxisome proliferator-activated receptor alpha Ligand BMS-68... 10 16
Delta-type opioid receptor and Mu-type opioid receptor Ligand ... 1 4
Fatty-acid amide hydrolase 1 Inhibitor 3-(benzo[d]oxazol-2-yl)... 1 6
Arachidonate 5-lipoxygenase Inhibitor 5-methyl-n-phenylbenzo[d... 5 13
Alpha-2B adrenergic receptor and Alpha-2C adrenergic receptor ... 4 4
Peroxisome proliferator-activated receptor delta and Peroxisom... 2 7
Peroxisome proliferator-activated receptor delta ligand SureCN... 8 19
Muscarinic acetylcholine receptor M3 ligand [(3R)-1-[3-(1,3-be... 3 2
Histamine H3 receptor and Potassium voltage-gated channel subf... 2 21
Histone deacetylase 1 and Histone deacetylase 2 inhibitor AGN-... 4 15
Prelamin-A/C inhibitor CHEMBL1374443 family 1 6
Thyroid hormone receptor beta ligand CHEMBL1397256 family 1 12
Inosine-5'-monophosphate dehydrogenase inhibitor SureCN1318237... 2 12
Fatty-acid amide hydrolase 1 inhibitor methyl 6-[2-[3-(4-pheny... 8 5
Fatty-acid amide hydrolase 1 inhibitor [(2S)-6-phenoxy-1,2,3,4... 3 6
High affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic ... 5 12
High affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic ... 4 1
Prostaglandin E2 receptor EP4 subtype ligand SureCN4876498 family 2 0
Peroxisome proliferator-activated receptor gamma and Peroxisom... 4 1
Sphingosine 1-phosphate receptor 1 ligand 6-[2-[4-phenyl-3-(tr... 2 3
Sphingosine 1-phosphate receptor 1 and Sphingosine 1-phosphate... 14 24
Oxysterols receptor LXR-alpha and Oxysterols receptor LXR-beta... 4 3
Peroxisome proliferator-activated receptor gamma and Peroxisom... 10 5
Fatty-acid amide hydrolase 1 inhibitor alpha-ketooxazole, 4jj ... 1 1
Fatty-acid amide hydrolase 1 inhibitor alpha-ketooxazole, 5a f... 2 1
Peroxisome proliferator-activated receptor gamma and Peroxisom... 5 0
Beta-2 adrenergic receptor and Beta-3 adrenergic receptor liga... 1 5
Peroxisome proliferator-activated receptor alpha ligand 5-[4-[... 1 0
Peroxisome proliferator-activated receptor gamma and Peroxisom... 7 2
Fatty-acid amide hydrolase 1 inhibitor AGN-PC-04UH7Y family 4 1
Neutrophil elastase inhibitor 1-[4-(1,3-benzoxazol-2-ylsulfany... 3 0
D(4) dopamine receptor ligand SureCN8704964 family 1 2
Reverse transcriptase/RNaseH inhibitor 3-[2-(4,7-dichloro-1,3-... 1 5
Metabotropic glutamate receptor 5 ligand SureCN504754 family 5 4
Reverse transcriptase/RNaseH inhibitor 3-[2-(4,7-difluoro-1,3-... 3 1
Glucocorticoid receptor and Progesterone receptor ligand (8S,1... 2 0
Metabotropic glutamate receptor 5 ligand 3-fluoro-5-(5-pyridin... 1 0
Fatty-acid amide hydrolase 1 inhibitor 7-phenyl-1-[5-[6-(2H-te... 2 0
Cholesteryl ester transfer protein inhibitor N-[4-(5-chloro-7-... 1 0
Cholesteryl ester transfer protein inhibitor AGN-PC-07R9U4 family 1 1
Reverse transcriptase/RNaseH inhibitor 3-[2-(1-benzofuran-2-yl... 1 1
Arachidonate 5-lipoxygenase inhibitor (4E)-4-[(E,4Z)-4-(3H-1,3... 6 6
Reverse transcriptase/RNaseH inhibitor 3-(1,3-benzoxazol-2-ylm... 1 0
(E)-2-(1,3-benzoxazol-2-yl)-3-(6-chloro-4H-1,3-benzodioxin-8-y... 1 0
2-enenitrile NP ZINC05025155 Family 2 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00159671 DCL000943 Clinical Trial Drug R 673
CFAMM00159696 DNC004657 Investigative Drug 1-Benzooxazol-2-yl-6-phenyl-hexan-1-one

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

27433 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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