CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFCD477
Family Name C-X-C chemokine receptor type 1 and C-X-C chemokine receptor type 2 Ligand Reparixin Family
No. of Seeds 5 No. of Other Members 30
Family Centroid CFAMM00159840 Functional Category Clinical Trial Drug with Natural Product
Superfamily C-X-C chemokine receptor type 1 and C-X-C chemokine receptor type 2 Ligand Reparixin Superfamily
Class Class 1125

Cousin Family NamesSeedsMembers
Sodium channel protein type 1 subunit alpha Ligand Phenacemide... 5 6
Alpha-1B adrenergic receptor Ligand Lisdexamfetamine Family 14 443
DNA Binder Procarbazine Family 8 358
Voltage-dependent T-type calcium channel subunit alpha-1I Liga... 2 9
Cytochrome P450 2D6 Inhibitor Glutethimide Family 1 1
Calcium-activated potassium channel subunit alpha-1 Ligand ICA... 14 14
Arachidonate 5-lipoxygenase Inhibitor N-hydroxy-4-isobutyl-ben... 4 43
Histone deacetylase Inhibitor CG-1521 Family 2 8
Chymase Inhibitor Phenylalanylmethane Family 1 8
Histone deacetylase 1 and Histone deacetylase 2 Inhibitor 7-bi... 5 14
Histone deacetylase 1 Inhibitor 8-(3-benzoyl-ureido)-octanoic ... 7 13
Histone deacetylase 1 and Histone deacetylase 2 Inhibitor 5-(4... 2 3
Angiopoietin-1 receptor and Cyclin-dependent kinase 1 Inhibito... 1 3
Cannabinoid receptor 1 Ligand N-(3,3-diphenyl)propyl-2-phenyla... 4 18
Histone deacetylase 1 Inhibitor N-hydroxy-6-oxo-6-phenylhexana... 7 7
Histone deacetylase 1 Inhibitor N-hydroxy-7-(naphthalen-2-yl)-... 3 2
Histone deacetylase 1 Inhibitor N-hydroxy-8-(naphthalen-2-yl)n... 6 3
Aminopeptidase N Inhibitor N1,2-dibenzyl-n3-hydroxymalonamide ... 5 23
Arachidonate 5-lipoxygenase Inhibitor N-hydroxy-n-methyl-2-nap... 3 3
Arachidonate 5-lipoxygenase Inhibitor Phenanthrene-3-carboxyli... 7 4
Arachidonate 5-lipoxygenase Inhibitor N-hydroxy-n-methyl-benza... 3 9
Arachidonate 5-lipoxygenase Inhibitor N-hydroxy-n-methyl-2,3,3... 1 0
Aminopeptidase N Inhibitor 2-cinnamamido-n4-hexyl-n1-hydroxysu... 24 8
Botulinum neurotoxin type A inhibitor 2-[3-(4-bromophenyl)-1-a... 1 0
Oxysterols receptor LXR-beta and Oxysterols receptor LXR-alpha... 2 0
Glutamate receptor 4 ligand N-[2-[4-(4-formylphenyl)phenyl]pro... 1 0
Protease inhibitor SureCN6172401 family 1 1


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00159840 DCL000955 Clinical Trial Drug Reparixin
CFAMM00159845 DNC005385 Investigative Drug (R)-N-Hydroxy-2-(4-isobutyl-phenyl)-propionamide
CFAMM00159852 DNC011692 Investigative Drug Ibuproxam
CFAMM00159847 DNC005386 Investigative Drug (R)-2-(4-Isobutyl-phenyl)-N-methoxy-propionamide
CFAMM00159846 DNC005387 Investigative Drug (R)-2-(4-Isobutyl-phenyl)-propionamide

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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