CFam Chemical Families Database
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Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFCD51
Family Name C-C chemokine receptor type 2 Ligand CCX915 Family
No. of Seeds 3 No. of Other Members 25
Family Centroid CFAMM00131285 Functional Category Clinical Trial Drug
Superfamily Insulin receptor Ligand Meglitinides Superfamily
Class Class 691

Cousin Family NamesSeedsMembers
D(2) dopamine receptor Ligand Nemonapride Family 70 283
Beta-2 adrenergic receptor Ligand Salmeterol Xinafoate Family 9 51
Insulin receptor Ligand Meglitinides Family 9 25
Integrin alpha-4 Inhibitor Firategrast Family 3 93
Microsomal triglyceride transfer protein large subunit Inhibit... 3 103
Cytochrome P450 2D6 and Delta-type opioid receptor Ligand 4-(s... 17 381
Guanylate cyclase soluble subunit beta-1 Inhibitor Cinaciguat ... 7 50
Potassium voltage-gated channel subfamily A member 3 Ligand 2-... 9 92
Peroxisome proliferator-activated receptor gamma and Peroxisom... 2 4
Melanin-concentrating hormone receptor 1 Ligand N-(1-benzylpip... 9 57
Fatty-acid amide hydrolase 1 Inhibitor 3'-carbamoylbiphenyl-3-... 8 50
D(2) dopamine receptor Ligand Epidepride Family 31 66
Peroxisome proliferator-activated receptor delta and Peroxisom... 20 8
Prostaglandin E2 receptor EP3 subtype and Prostaglandin E2 rec... 55 36
Prostaglandin E2 receptor EP3 subtype and Prostaglandin E2 rec... 8 12
D(2) dopamine receptor ligand 2-bromo-3-chloro-N-[[(2S)-1-ethy... 1 1
D(2) dopamine receptor ligand 2-chloro-3-ethyl-N-[[(2S)-1-ethy... 3 0
Integrin beta-3 and Integrin alpha-IIb inhibitor (3R)-7-[(4-ca... 3 14
Prostaglandin D2 receptor 2 and Prostaglandin D2 receptor liga... 12 0
5-hydroxytryptamine receptor 3A and 5-hydroxytryptamine recept... 11 6
Prostaglandin E2 receptor EP4 subtype ligand 4-[(1S)-1-[[2-(tr... 2 1
Kinesin-like protein KIF11 and Potassium voltage-gated channel... 1 0
Peroxisome proliferator-activated receptor delta and Peroxisom... 13 0
C-C chemokine receptor type 1 ligand [2-[(2S)-3-(5-chlorospiro... 3 0
C-C chemokine receptor type 1 ligand 2-[(2S)-3-(5-chlorospiro[... 2 3
Histamine H3 receptor and Sodium-dependent serotonin transport... 14 3
Beta-3 adrenergic receptor and Beta-1 adrenergic receptor liga... 15 13
Beta-3 adrenergic receptor and Beta-1 adrenergic receptor liga... 14 1
Kappa-type opioid receptor and Mu-type opioid receptor ligand ... 1 0
Integrin beta-1 and Integrin alpha-4 inhibitor SureCN6627432 f... 6 1
5-hydroxytryptamine receptor 2C and 5-hydroxytryptamine recept... 1 2
Sodium-dependent serotonin transporter and Sodium-dependent no... 3 0
Beta-3 adrenergic receptor ligand 5-[[(7S)-7-[[(2R)-2-(3-chlor... 6 3
Beta-3 adrenergic receptor ligand 4-[4-[2-[[(2R)-2-(4-aminophe... 3 0
Beta-3 adrenergic receptor and Beta-1 adrenergic receptor liga... 3 0
Integrin beta-1 and Integrin alpha-4 inhibitor (2S)-2-[(2-chlo... 2 4
Nonstructural protein 1 and Thioredoxin glutathione reductase ... 1 0
Potassium voltage-gated channel subfamily H member 2 ligand me... 3 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00131283 CHEMBL591666 Bioactive 847728-01-2
CFAMM00131285 DCL000080 Clinical Trial Drug CCX915
CFAMM00131286 DNC010378 Investigative Drug NSC-319745

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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