CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFCD524
Family Name Aurora kinase B and Aurora kinase A Inhibitor PHA-739358 Family
No. of Seeds 6 No. of Other Members 29
Family Centroid CFAMM00162933 Functional Category Clinical Trial Drug
Superfamily Aurora kinase B and Aurora kinase A Inhibitor PHA-739358 Superfamily
Class Class 1152

Cousin Family NamesSeedsMembers
Fibroblast growth factor receptor 1 Ligand AZD4547 Family 1 0
Cyclin-dependent kinase 2 Inhibitor N-(5-cyclopropyl-1h-pyrazo... 6 62
Aurora kinase B and Aurora kinase C Inhibitor PHA-680632 Family 5 72
Poly [ADP-ribose] polymerase 1 inhibitor 2-[2-[4-(1H-indazol-3... 1 0
Aurora kinase A inhibitor SureCN3894803 family 5 8
Receptor-type tyrosine-protein kinase FLT3 and Vascular endoth... 2 6
Receptor-type tyrosine-protein kinase FLT3 and Vascular endoth... 3 15
Receptor-type tyrosine-protein kinase FLT3 and Vascular endoth... 1 0
Receptor-type tyrosine-protein kinase FLT3 ligand pyridin-3-yl... 2 1
Receptor-type tyrosine-protein kinase FLT3 ligand (5-methyl-1,... 1 6
Serine/threonine-protein kinase PAK 4 inhibitor [(1S)-2-(dimet... 4 0
Receptor-type tyrosine-protein kinase FLT3 and Vascular endoth... 4 0
Glycogen synthase kinase-3 alpha and Glycogen synthase kinase-... 4 4
Adenosine receptor A2b and Adenosine receptor A2a ligand SureC... 1 0
Neuropeptide Y receptor type 5 ligand SureCN917790 family 9 0
Cyclin-A2 and Cyclin-dependent kinase 2 inhibitor 1-[6,6-dimet... 1 0
Cyclin-A2 and Cyclin-dependent kinase 2 inhibitor AGN-PC-0A9RU... 2 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00162905 CHEMBL2063319 Bioactive benzyl N-[4-[3-[[4-(4-methylpiperazin-1-yl)benzoyl]amino]-1H-pyrazol-5-yl]phenyl]carbamate
CFAMM00162902 CHEMBL1981047 Bioactive S1107_Selleck
CFAMM00162907 CHEMBL385872 Bioactive 5-Amido-pyrrolopyrazole 9b
CFAMM00162919 CHEMBL2064562 Bioactive [(1S)-2-(dimethylamino)-1-phenylethyl] 3-[(4-fluorobenzoyl)amino]-6,6-dimethyl-1,4-dihydropyrrolo[3,4-c]pyrazole-5-carboxylate
CFAMM00162926 CHEMBL2063323 Bioactive benzyl N-[[4-[3-[[4-(4-methylpiperazin-1-yl)benzoyl]amino]-1H-pyrazol-5-yl]phenyl]methyl]carbamate
CFAMM00162933 DCL001078 Clinical Trial Drug PHA-739358

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

24631 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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