CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFCD525
Family Name Cyclin-dependent kinase 1 and Cyclin-dependent kinase 2 Inhibitor R547 Family
No. of Seeds 5 No. of Other Members 12
Family Centroid CFAMM00162941 Functional Category Clinical Trial Drug
Superfamily Cyclin-dependent kinase 1 and Cyclin-dependent kinase 2 Inhibitor R547 Superfamily
Class Class 850

Cousin Family NamesSeedsMembers
Tyrosine-protein kinase JAK3 and Tyrosine-protein kinase JAK2 ... 1 11
Mitogen-activated protein kinase 14 inhibitor N-(4-aminobutyl)... 1 28
Muscarinic acetylcholine receptor M2 and Muscarinic receptor 3... 4 3
Calcium/calmodulin-dependent protein kinase kinase 2 and Focal... 3 17
Rho-associated protein kinase 1 and cAMP-dependent protein kin... 1 11
Cathepsin K and Cathepsin L1 inhibitor 2-Cyano-pyrimidine, 17a... 5 8
Aurora kinase B and Aurora kinase A inhibitor 2-fluoro-6-metho... 2 0
Tyrosine-protein kinase Lck and Mitogen-activated protein kina... 2 1
Dihydrofolate reductase and Bifunctional dihydrofolate reducta... 3 21


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00162943 CHEMBL268507 Bioactive SureCN3517632
CFAMM00162948 CHEMBL213713 Bioactive [4-amino-2-[(1-methylsulfonylpiperidin-4-yl)amino]pyrimidin-5-yl]-(2,3,4-trifluoro-6-methoxyphenyl)methanone
CFAMM00162940 CHEMBL385733 Bioactive SureCN4355426
CFAMM00162938 CHEMBL215086 Bioactive SureCN4356420
CFAMM00162941 DCL001079 Clinical Trial Drug R547

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

26816 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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