CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFCD526
Family Name Cyclin-dependent kinase 1 and Cyclin-dependent kinase 2 Inhibitor Sch 727965 Family
No. of Seeds 1 No. of Other Members 2
Family Centroid CFAMM00162956 Functional Category Clinical Trial Drug
Superfamily Cyclin-dependent kinase 1 and Cyclin-dependent kinase 2 Inhibitor Sch 727965 Superfamily
Class Class 1134

Cousin Family NamesSeedsMembers
Corticotropin-releasing factor receptor 1 Ligand CRF-1 Antagon... 29 421
Adenosine receptor A1 Ligand SLV320 Family 6 79
Aurora kinase B and Aurora kinase C Inhibitor GSK1070916 Family 53 580
Corticotropin-releasing factor receptor 1 Ligand R121919 Family 26 84
Vascular endothelial growth factor receptor 1 and Vascular end... 6 23
Mitogen-activated protein kinase 8 and Mitogen-activated prote... 2 5
cGMP-specific 3',5'-cyclic phosphodiesterase inhibitor AGN-PC-... 34 11
Serine/threonine-protein kinase mTOR and Phosphatidylinositol ... 46 9
Ephrin type-B receptor 4 ligand SureCN3289519 family 4 2
Serine/threonine-protein kinase mTOR and Phosphatidylinositol ... 13 10
Serine/threonine-protein kinase mTOR and Phosphatidylinositol ... 4 1
5-hydroxytryptamine receptor 1D and 5-hydroxytryptamine recept... 14 13
Tyrosine-protein kinase JAK2 and Tyrosine-protein kinase JAK3 ... 6 1
G1/S-specific cyclin-E1 and Cyclin-dependent kinase 2 inhibito... 1 5
Adenosine kinase inhibitor N-cyclopropyl-2-[[1-[(2R,3R,4S,5R)-... 4 1
Nociceptin receptor and Potassium voltage-gated channel subfam... 10 1
Receptor-type tyrosine-protein kinase FLT3 and Mast/stem cell ... 2 3
Tyrosine-protein kinase JAK2 and Tyrosine-protein kinase JAK3 ... 6 0
Mitogen-activated protein kinase 8 and Mitogen-activated prote... 2 1
Tyrosine-protein kinase JAK2 inhibitor [4-[[5-(1-ethylpyrazol-... 2 3
Serine/threonine-protein kinase pim-1 and Glycogen synthase ki... 1 1
Serine/threonine-protein kinase mTOR and Phosphatidylinositol ... 26 0
Corticotropin-releasing factor receptor 1 ligand 3-[6-(dimethy... 1 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00162956 DCL001081 Clinical Trial Drug SCH 727965

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

26821 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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