CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFCD531
Family Name Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform Inhibitor GSK1059615 Family
No. of Seeds 2 No. of Other Members 2
Family Centroid CFAMM00163359 Functional Category Clinical Trial Drug
Superfamily Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform Inhibitor GSK1059615 Superfamily
Class Class 64

Cousin Family NamesSeedsMembers
Neuromedin-K receptor Ligand SB222200 Family 17 235
Glutamate receptor AMPA subtype Ligand CX-516 Family 9 24
Histone deacetylase 6 Inhibitor N-(quinolin-3-yl)-6-(sulfamoyl... 4 8
Metabotropic glutamate receptor 5 Ligand 3-m-tolyl-1,5-naphthy... 6 10
Metabotropic glutamate receptor 1 Ligand N-(2-phenylpropyl)qui... 3 1
Platelet-activating factor receptor ligand YM-461 family 1 11
Cyclin-dependent kinase 1 and G2/mitotic-specific cyclin-B1 in... 2 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00163359 DCL001089 Clinical Trial Drug GSK1059615
CFAMM00163364 DNC003455 Investigative Drug 5-QUINOXALIN-6-YLMETHYLENE-THIAZOLIDINE-2,4-DIONE

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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