CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

Family Name Histamine H3 receptor Ligand Cipralisant Family
No. of Seeds 36 No. of Other Members 70
Family Centroid CFAMM00131498 Functional Category Clinical Trial Drug
Superfamily Histamine H3 receptor Ligand Cipralisant Superfamily
Class Class 464

Cousin Family NamesSeedsMembers
Histamine receptor Ligand Histamine Phosphate Family 6 78
Cadherin-2 Inhibitor Exherin Family 2 9
Histamine H3 receptor and Histamine H4 receptor Ligand Thioper... 8 12
Histamine H3 receptor and Histamine H4 receptor Ligand (r)-3-(... 26 80
Histamine H3 receptor Ligand GT-2016 Family 4 6
Histamine H2 receptor and Histamine H3 receptor ligand N,N'-bi... 2 1
Histamine H3 receptor ligand SureCN7961197 family 1 0
Histamine H2 receptor and Histamine H1 receptor ligand N-[N'-[... 1 2
Histamine H3 receptor ligand SureCN7961024 family 2 0
NP Agn-pc-05c64v Family 2 2


External ID

Functional Category

Molecule Name

CFAMM00131409 CHEMBL79983 Bioactive SureCN8508488
CFAMM00131462 CHEMBL354374 Bioactive GT-2331
CFAMM00131436 CHEMBL368398 Bioactive 213027-19-1
CFAMM00131492 CHEMBL434495 Bioactive SureCN8397428
CFAMM00131388 CHEMBL72156 Bioactive 1H-Imidazole-4-butanimidamide
CFAMM00131464 CHEMBL45369 Bioactive 5-[2-(4,4-dimethylpent-1-ynyl)cyclopropyl]-1H-imidazole
CFAMM00131442 CHEMBL313127 Bioactive 5-[(3R,4R)-4-methylpyrrolidin-3-yl]-1H-imidazole
CFAMM00131447 CHEMBL325327 Bioactive 2-[3-(1H-imidazol-5-yl)propyl]guanidine
CFAMM00131453 CHEMBL83917 Bioactive 5-[(3S,4S)-4-methylpyrrolidin-3-yl]-1H-imidazole
CFAMM00131424 CHEMBL170598 Bioactive 5-(2-pent-1-ynylcyclopropyl)-1H-imidazole
CFAMM00131431 CHEMBL83271 Bioactive 5-[(3S,4R)-4-methylpyrrolidin-3-yl]-1H-imidazole
CFAMM00131498 DCL000088 Clinical Trial Drug Cipralisant
CFAMM00131414 DNC011830 Investigative Drug (1R,2R)-2-(1H-Imidazol-4-yl)-1-methyl-propylamine
CFAMM00131446 DNC011619 Investigative Drug 4-Hex-3-ynyl-1H-imidazole
CFAMM00131430 DNC011628 Investigative Drug 4-(7-Methyl-oct-3-ynyl)-1H-imidazole
CFAMM00131463 DNC011844 Investigative Drug (1R,2S)-2-(1H-Imidazol-4-yl)-1-methyl-propylamine
CFAMM00131445 DNC011591 Investigative Drug VUF-5296
CFAMM00131500 DNC012914 Investigative Drug 4-((1H-imidazol-4-yl)methyl)-1-heptylpiperidine
CFAMM00131407 DNC011538 Investigative Drug C-[2-(1H-Imidazol-4-yl)-cyclopropyl]-methylamine
CFAMM00131486 DNC011544 Investigative Drug VUF-5297
CFAMM00131475 DNC011575 Investigative Drug 2-[2-(1H-Imidazol-4-yl)-cyclopropyl]-ethylamine
CFAMM00131450 DNC011852 Investigative Drug 4-((2R,3S)-2-Methyl-pyrrolidin-3-yl)-1H-imidazole
CFAMM00131485 DNC011606 Investigative Drug 4-Hept-3-ynyl-1H-imidazole
CFAMM00131412 DNC011838 Investigative Drug 4-((2S,3R)-2-Methyl-pyrrolidin-3-yl)-1H-imidazole
CFAMM00131411 DNC011659 Investigative Drug 4-(6-Cyclohexyl-hex-3-ynyl)-1H-imidazole
CFAMM00131403 DNC011665 Investigative Drug 4-(6-Cyclopentyl-hex-3-ynyl)-1H-imidazole
CFAMM00131491 DNC011536 Investigative Drug 2-(1H-Imidazol-4-yl)-cyclopropylamine
CFAMM00131459 DNC002345 Investigative Drug Immepip
CFAMM00131425 DNC011643 Investigative Drug 4-(7,7-Dimethyl-oct-3-ynyl)-1H-imidazole
CFAMM00131384 DNC002371 Investigative Drug VUF 5681
CFAMM00131415 DNC011834 Investigative Drug (1S,2S)-2-(1H-Imidazol-4-yl)-cyclopentylamine
CFAMM00131479 DNC002355 Investigative Drug Methimepip

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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