CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFCD586
Family Name JNJ-39439335 family
No. of Seeds 5 No. of Other Members 11
Family Centroid CFAMM00165539 Functional Category Clinical Trial Drug
Superfamily JNJ-39439335 Superfamily
Class Class 1184

Cousin Family NamesSeedsMembers
Histamine H1 receptor Ligand Mizolastine Family 14 603
Voltage-dependent T-type calcium channel subunit alpha-1I Liga... 1 2
Tryptase Inhibitor Babim Family 12 90
Adenosine receptor A1 and Adenosine receptor A2a Ligand 2,6-di... 13 14
Vascular endothelial growth factor receptor 2 Ligand 6-(1h-ben... 2 5
Plasminogen and Prothrombin Inhibitor 2-(2-hydroxy-phenyl)-1h-... 3 69
Dipeptidyl peptidase 4 Inhibitor (5-phenyl-3h-benzo[d]imidazol... 5 13
Sodium channel protein type 1 subunit alpha and Sodium channel... 10 14
Glutamate receptor ionotropic, NMDA 1 and Glutamate receptor i... 4 3
Neuropeptide Y receptor type 5 and Potassium voltage-gated cha... 6 0
Transient receptor potential M8 protein ligand 2-[(E)-2-(oxan-... 5 3
Transient receptor potential cation channel subfamily M member... 9 0
Transient receptor potential M8 protein and Cytochrome P450 2C... 4 0
Transient receptor potential M8 protein and Cytochrome P450 2C... 1 0
Sodium-dependent dopamine transporter and Sodium-dependent nor... 2 3
Mitogen-activated protein kinase 14 inhibitor 6-[5-(2,4-difluo... 9 3
Neuronal acetylcholine receptor subunit beta-2 and Neuronal ac... 10 6
Glutamate receptor ionotropic, NMDA 2B and Glutamate receptor ... 4 11
Plasma kallikrein and Coagulation factor VII inhibitor 2-[(3E)... 15 49
Coagulation factor VII inhibitor 2-[(3E)-3-(5-carbamimidoyl-1,... 3 1
Serine/threonine-protein kinase Chk1 inhibitor SureCN6387344 f... 6 11
Melanin-concentrating hormone receptor 1 ligand AGN-PC-00BSP9 ... 6 12
Coagulation factor VII inhibitor [3-[(5E)-5-(5-carbamimidoyl-1... 3 2
Mitogen-activated protein kinase 14 inhibitor 6-[2-(2,6-difluo... 3 0
Kappa-type opioid receptor and Mu-type opioid receptor ligand ... 2 0
Histone-arginine methyltransferase CARM1 inhibitor AGN-PC-07CR... 4 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00165545 CHEMBL1650519 Bioactive (3E)-3-[5-[2-fluoro-6-(trifluoromethyl)phenyl]benzimidazol-2-ylidene]-1-oxa-2-azaspiro[4.5]decane
CFAMM00165541 CHEMBL1650510 Bioactive (3E)-3-[5-[2-(trifluoromethyl)phenyl]benzimidazol-2-ylidene]-1-oxa-2-azaspiro[4.5]decane
CFAMM00165540 CHEMBL1650513 Bioactive 2-[2-[(2E)-2-(1-oxa-2-azaspiro[4.5]decan-3-ylidene)benzimidazol-5-yl]phenyl]propan-2-ol
CFAMM00165553 CHEMBL1650530 Bioactive (3E)-8,8-difluoro-3-[5-[2-(trifluoromethyl)phenyl]benzimidazol-2-ylidene]-1-oxa-2-azaspiro[4.5]decane
CFAMM00165539 DNCL001608 Clinical Trial Drug JNJ-39439335

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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