CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFCD587
Family Name TG-C family
No. of Seeds 11 No. of Other Members 208
Family Centroid CFAMM00165732 Functional Category Clinical Trial Drug with Human Metabolite
Superfamily Adenosine receptor A2a Binder Superfamily
Class Class 172

Cousin Family NamesSeedsMembers
Adenosine receptor A3 ligand purine nucleoside Adenosine Family 47 847
DNA Binder purine nucleoside Adenosine analog Nelarabine Family 2 10
NADH-ubiquinone oxidoreductase chain 3 Inhibitor Nadh Family 4 11
Bucladesine family 1 1
Adenosine receptor A2a Ligand Atl-146e Family 33 94
P2Y purinoceptor 12 Inhibitor Ar-c69931 Mx Family 10 18
Histamine N-methyltransferase Inhibitor S-adenosyl-l-homocyste... 2 3
cAMP-dependent protein kinase type I-alpha regulatory subunit ... 12 0
Adenosine receptor A3 and Adenosine receptor A1 ligand (2S,3S,... 16 6


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00165607 CHEMBL1161860 Bioactive [[(2R,3S,4R,5R)-5-(6-aminopurin-9-yl)-4-hydroxy-3-phosphonooxyoxolan-2-yl]methoxy-hydroxyphosphoryl] [(3R)-3-hydroxy-2,2-dimethyl-4-oxo-4-[[3-oxo-3-[2-[2-oxo-2-(3-piperazin-1-ylpropylamino)ethyl]sulfanylethylamino]propyl]amino]butyl] hydrogen phosphate
CFAMM00165764 CHEMBL1161852 Bioactive [[(3R)-4-[[3-[2-[2-[[(2R,3S,4R,5R,6S)-5-amino-3,4-dihydroxy-6-methoxyoxan-2-yl]methylamino]-2-oxoethyl]sulfanylethylamino]-3-oxopropyl]amino]-3-hydroxy-2,2-dimethyl-4-oxobutoxy]-hydroxyphosphoryl] [(2R,3S,4R,5R)-5-(6-aminopurin-9-yl)-4-hydroxy-3-phosphonooxyoxolan-2-yl]methyl hydrogen phosphate
CFAMM00165643 CHEMBL1161859 Bioactive [[(2R,3S,4R,5R)-5-(6-aminopurin-9-yl)-4-hydroxy-3-phosphonooxyoxolan-2-yl]methoxy-hydroxyphosphoryl] [(3R)-3-hydroxy-2,2-dimethyl-4-oxo-4-[[3-oxo-3-[2-[2-oxo-2-(2-piperazin-1-ylethylamino)ethyl]sulfanylethylamino]propyl]amino]butyl] hydrogen phosphate
CFAMM00165769 CHEMBL1161857 Bioactive [[(3R)-4-[[3-[2-[2-[[(2S)-1-amino-5-(diaminomethylideneamino)-1-oxopentan-2-yl]amino]-2-oxoethyl]sulfanylethylamino]-3-oxopropyl]amino]-3-hydroxy-2,2-dimethyl-4-oxobutoxy]-hydroxyphosphoryl] [(2R,3S,4R,5R)-5-(6-aminopurin-9-yl)-4-hydroxy-3-phosphonooxyoxolan-2-yl]methyl hydrogen phosphate
CFAMM00165774 CHEMBL1161858 Bioactive [[(2R,3S,4R,5R)-5-(6-aminopurin-9-yl)-4-hydroxy-3-phosphonooxyoxolan-2-yl]methoxy-hydroxyphosphoryl] [(3R)-4-[[3-[2-[2-[3-[3-(dimethylamino)propylamino]propylamino]-2-oxoethyl]sulfanylethylamino]-3-oxopropyl]amino]-3-hydroxy-2,2-dimethyl-4-oxobutyl] hydrogen phosphate
CFAMM00165732 DNCL001621 Clinical Trial Drug TG-C
CFAMM00165709 DNC003037 Investigative Drug Coenzyme A
CFAMM00165588 DNC003157 Investigative Drug Dephospho Coenzyme A
CFAMM00165711 DNC002631 Investigative Drug Acetoacetyl-Coenzyme A
CFAMM00165620 DNC003388 Investigative Drug 3r-Hydroxydecanoyl-Coa
CFAMM00165565 DNC003091 Investigative Drug Myristoyl-Coa

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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