CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFCD601
Family Name VTP-27999 family
No. of Seeds 24 No. of Other Members 23
Family Centroid CFAMM00165941 Functional Category Clinical Trial Drug
Superfamily VTP-27999 Superfamily
Class Class 1195

Cousin Family NamesSeedsMembers
Integrin beta-3 Inhibitor RWJ-53419 Family 6 65
Adenosine receptor A3 and Mu-type opioid receptor Ligand GBR-1... 80 110
Cathepsin S inhibitor ethyl 2-[[3-[[(2S)-3-cyclohexyl-2-[(1-me... 3 8
Pol polyprotein inhibitor benzyl N-[(2S)-1-[[(2S,3S,4R,5S)-3,4... 21 5
Peptidyl-prolyl cis-trans isomerase FKBP1A and Peptidyl-prolyl... 4 27
Cathepsin S inhibitor SureCN7397817 family 9 4
Renin inhibitor SureCN1865980 family 9 4
C-C chemokine receptor type 1 ligand N-[(2R)-1-[(4S)-4-(4-chlo... 15 6
Pol polyprotein inhibitor AC1LA3C0 family 2 18
Renin inhibitor SureCN1858210 family 9 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00165966 CHEMBL590866 Bioactive SureCN3612889
CFAMM00165959 CHEMBL592762 Bioactive SureCN3601543
CFAMM00165972 CHEMBL2023123 Bioactive methyl N-[2-[(R)-(3-chlorophenyl)-[(3R)-1-[[(1S,2R)-1-cyclohexyl-1-hydroxy-3-(methylamino)propan-2-yl]carbamoyl]piperidin-3-yl]methoxy]ethyl]carbamate
CFAMM00165978 CHEMBL606238 Bioactive SureCN3614920
CFAMM00165958 CHEMBL497624 Bioactive SureCN1859893
CFAMM00165971 CHEMBL2023122 Bioactive methyl N-[2-[(R)-(3-chlorophenyl)-[(3R)-1-[[(2S)-1-(methylamino)-3-[(3S)-oxan-3-yl]propan-2-yl]carbamoyl]piperidin-3-yl]methoxy]ethyl]carbamate
CFAMM00165977 CHEMBL591578 Bioactive SureCN3606103
CFAMM00165944 CHEMBL496224 Bioactive SureCN1867227
CFAMM00165970 CHEMBL590388 Bioactive SureCN3616594
CFAMM00165950 CHEMBL591340 Bioactive SureCN3609351
CFAMM00165937 CHEMBL2024248 Bioactive methyl N-[2-[(R)-(3-chlorophenyl)-[(3R)-1-[[(2S)-1-(methylamino)-3-[(3R)-oxan-3-yl]propan-2-yl]carbamoyl]piperidin-3-yl]methoxy]ethyl]carbamate
CFAMM00165943 CHEMBL1276678 Bioactive methyl N-[2-[(R)-(3-chlorophenyl)-[(3R)-1-[[(2S)-2-(methylamino)-3-[(3R)-oxan-3-yl]propyl]carbamoyl]piperidin-3-yl]methoxy]ethyl]carbamate
CFAMM00165969 CHEMBL590623 Bioactive SureCN3604114
CFAMM00165949 CHEMBL591341 Bioactive SureCN3612804
CFAMM00165962 CHEMBL590868 Bioactive SureCN3610651
CFAMM00165975 CHEMBL605408 Bioactive SureCN3610360
CFAMM00165955 CHEMBL591104 Bioactive SureCN9996300
CFAMM00165935 CHEMBL2023124 Bioactive methyl N-[2-[(R)-(3-chlorophenyl)-[(3R)-1-[[(2S)-1-(methylamino)-3-(oxan-4-yl)propan-2-yl]carbamoyl]piperidin-3-yl]methoxy]ethyl]carbamate
CFAMM00165948 CHEMBL591342 Bioactive SureCN3605727
CFAMM00165961 CHEMBL592765 Bioactive SureCN3606559
CFAMM00165954 CHEMBL591105 Bioactive SureCN3606481
CFAMM00165960 CHEMBL592763 Bioactive SureCN8234746
CFAMM00165973 CHEMBL589647 Bioactive SureCN3606603
CFAMM00165941 DNCL001733 Clinical Trial Drug VTP-27999

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

26816 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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