CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

Family Name Platelet-activating factor acetylhydrolase Inhibitor Darapladib Family
No. of Seeds 15 No. of Other Members 3
Family Centroid CFAMM00132183 Functional Category Clinical Trial Drug
Superfamily Platelet-activating factor acetylhydrolase Inhibitor Darapladib Superfamily
Class Class 865

Cousin Family NamesSeedsMembers
Platelet-activating factor acetylhydrolase inhibitor SureCN428... 2 0
Platelet-activating factor acetylhydrolase and Cytochrome P450... 3 0


External ID

Functional Category

Molecule Name

CFAMM00132197 CHEMBL10604 Bioactive SureCN3537843
CFAMM00132189 CHEMBL274551 Bioactive SureCN4287239
CFAMM00132182 CHEMBL10663 Bioactive SureCN4280069
CFAMM00132196 CHEMBL10441 Bioactive SureCN4287591
CFAMM00132195 CHEMBL10769 Bioactive SureCN4287911
CFAMM00132187 CHEMBL10659 Bioactive SureCN4283520
CFAMM00132186 CHEMBL268764 Bioactive N-[2-(diethylamino)ethyl]-2-[2-[(4-fluorophenyl)methylsulfanyl]-6-methyl-4-oxopyrimidin-1-yl]-N-[[4-[4-(trifluoromethyl)phenyl]phenyl]methyl]acetamide
CFAMM00132200 CHEMBL10600 Bioactive SureCN4285999
CFAMM00132192 CHEMBL275128 Bioactive SureCN4279189
CFAMM00132185 CHEMBL10502 Bioactive SureCN4286349
CFAMM00132191 CHEMBL10271 Bioactive SureCN4290715
CFAMM00132184 CHEMBL10501 Bioactive SureCN4281910
CFAMM00132198 CHEMBL10532 Bioactive SureCN4278306
CFAMM00132190 CHEMBL10759 Bioactive SureCN4286322
CFAMM00132183 DCL000102 Clinical Trial Drug Darapladib

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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