CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

Family Name Prostaglandin D2 receptor 2 and Prostaglandin D2 receptor Ligand Amg 853 Family
No. of Seeds 17 No. of Other Members 31
Family Centroid CFAMM00167163 Functional Category Clinical Trial Drug
Superfamily Prostaglandin D2 receptor 2 and Prostaglandin D2 receptor Ligand Amg 853 Superfamily
Class Class 1220

Cousin Family NamesSeedsMembers
Solute carrier family 12 member 1 Inhibitor Bumetanide Family 2 11
Stromelysin-1 Inhibitor PG-530742 Family 4 23
Prostaglandin D2 receptor and Prostacyclin receptor ligand 2-[... 15 5
C-C chemokine receptor type 2 ligand 4-[4-chloro-2-[[4-chloro-... 7 5
Prostaglandin D2 receptor 2 and Prostaglandin D2 receptor liga... 18 2
Prostaglandin D2 receptor and Prostaglandin D2 receptor 2 liga... 1 1
Prostaglandin D2 receptor 2 ligand 2-[4-methoxy-3-[2-[[(1S)-1-... 5 28
Prostaglandin D2 receptor and Prostaglandin D2 receptor 2 liga... 1 0
Prostaglandin D2 receptor 2 and Prostaglandin D2 receptor liga... 1 0
Integrin alpha-4 inhibitor SureCN14558471 family 16 2
Prostaglandin D2 receptor 2 ligand AGN-PC-07CQC5 family 4 0


External ID

Functional Category

Molecule Name

CFAMM00167177 CHEMBL1951563 Bioactive 2-[4-[4-(butylcarbamoyl)-2-[(2,4-dichlorophenyl)sulfonylamino]phenoxy]-3-chlorophenyl]acetic acid
CFAMM00167143 CHEMBL585197 Bioactive AGN-PC-07CQCI
CFAMM00167170 CHEMBL570001 Bioactive AGN-PC-07CQDK
CFAMM00167149 CHEMBL1951573 Bioactive 2-[5-chloro-4-[2-[[2-chloro-4-(trifluoromethoxy)phenyl]sulfonylamino]-4-(cyclobutylcarbamoyl)phenoxy]-2-fluorophenyl]acetic acid
CFAMM00167142 CHEMBL570670 Bioactive AGN-PC-07CQD6
CFAMM00167182 CHEMBL1951566 Bioactive 2-[4-[4-(butylcarbamoyl)-2-[(2,4-dichlorophenyl)sulfonylamino]phenoxy]-2,5-difluorophenyl]acetic acid
CFAMM00167175 CHEMBL1951402 Bioactive 2-[3-chloro-4-[2-[(4-chlorophenyl)sulfonylamino]-4-(cyclobutylcarbamoyl)phenoxy]phenyl]acetic acid
CFAMM00167141 CHEMBL583453 Bioactive AGN-PC-07CQCF
CFAMM00167181 CHEMBL1951567 Bioactive 2-[3-chloro-4-[4-(cyclopropylcarbamoyl)-2-[(2,4-dichlorophenyl)sulfonylamino]phenoxy]phenyl]acetic acid
CFAMM00167180 CHEMBL1951564 Bioactive 2-[4-[4-(butylcarbamoyl)-2-[(2,4-dichlorophenyl)sulfonylamino]phenoxy]-3-fluorophenyl]acetic acid
CFAMM00167173 CHEMBL1951568 Bioactive 2-[3-chloro-4-[4-(cyclobutylcarbamoyl)-2-[(2,4-dichlorophenyl)sulfonylamino]phenoxy]phenyl]acetic acid
CFAMM00167152 CHEMBL1951574 Bioactive 2-[4-[4-(tert-butylcarbamoyl)-2-[[2-chloro-4-(trifluoromethoxy)phenyl]sulfonylamino]phenoxy]-5-chloro-2-fluorophenyl]acetic acid
CFAMM00167145 CHEMBL1951555 Bioactive 2-[4-[4-(tert-butylcarbamoyl)-2-[(4-chlorophenyl)sulfonylamino]phenoxy]-3-chlorophenyl]acetic acid
CFAMM00167172 CHEMBL1951569 Bioactive 2-[4-[4-(tert-butylcarbamoyl)-2-[(2,4-dichlorophenyl)sulfonylamino]phenoxy]-3-chlorophenyl]acetic acid
CFAMM00167151 CHEMBL1951571 Bioactive 2-[4-[2-[[2-chloro-4-(trifluoromethyl)phenyl]sulfonylamino]-4-(cyclobutylcarbamoyl)phenoxy]-2,5-difluorophenyl]acetic acid
CFAMM00167178 CHEMBL1951562 Bioactive 2-[4-[4-(butylcarbamoyl)-2-[(2,4-dichlorophenyl)sulfonylamino]phenoxy]-3-methylphenyl]acetic acid
CFAMM00167163 DNCL002051 Clinical Trial Drug AMG 853

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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