CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFCD650
Family Name CBP-501 family
No. of Seeds 7 No. of Other Members 8
Family Centroid CFAMM00167237 Functional Category Clinical Trial Drug
Superfamily Bacterial outer membrane Inhibitor Daptomycin Superfamily
Class Class 647

Cousin Family NamesSeedsMembers
Leutinizing-hormone-releasing hormone inhibitor peptide Leupro... 43 911
Epidermal Growth Factor family 111 209
HIV protease Inhibitor Indinavir Family 36 211
HIV protease Inhibitor Saquinavir Family 64 428
Gastrin/cholecystokinin type B receptor ligand peptide Pentaga... 26 1171
Parathyroid hormone/parathyroid hormone-related peptide recept... 55 256
Somatostatin receptor type 2 ligand octapeptide Octreotide Family 27 172
Insulin receptor Ligand Insulin, Porcine Family 61 205
HIV-1 protease Inhibitor Atazanavir Family 16 58
Insulin-degrading enzyme inhibitor cyclic polypeptide Bacitrac... 30 259
Gastrin/cholecystokinin type B receptor ligand oligopeptide Ce... 35 209
Renin Inhibitor Remikiren Family 100 126
Indoleamine 2,3-dioxygenase 1 Inhibitor L-tryptophan Family 8 328
Bacterial outer membrane Inhibitor Daptomycin Family 6 50
Somatostatin receptor type 2 ligand octapeptide Lanreotide Family 93 156
ostatin receptor 5 Ligand Pasireotide Diaspartate Family 11 151
Substance-P receptor Ligand GSK424887 Family 8 184
Growth hormone receptor Ligand EP-51216 Family 34 390
NS5A protein Inhibitor Bms 790052 Family 5 9
Cholecystokinin receptor type A Ligand A-71378 Family 77 23
Gastrin/cholecystokinin type B receptor Ligand PD136450 Family 53 117
Lethal factor Inhibitor GM6001 Family 50 435
Renin Inhibitor Enalkiren Family 56 44
Somatostatin receptor type 2 Ligand L-054852 Family 13 88
Renin Inhibitor (h-261)boc-his-pro-phe-his-leu(oh)-val-ile-his... 33 41
Substance-K receptor and Substance-P receptor Ligand L-732138 ... 8 147
Cathepsin B and Cathepsin K Inhibitor Z-arg-leu-val-agly-ile-v... 3 19
Renin Inhibitor Sul-pro-phe-n-mehis-lva-ile-amp Family 47 54
Delta-type opioid receptor and Gastrin/cholecystokinin type B ... 19 0
Melanocortin receptor 3 and Melanocortin receptor 4 Ligand C[n... 12 10
Melanocortin receptor Ligand Ac-his-dnal(2)-arg-trp-nh2 Family 112 67
Cholecystokinin receptor type A Ligand VL-0395 Family 12 117
Melanocortin receptor 3 and Melanocortin receptor 4 Ligand Ac-... 38 60
Delta-type opioid receptor Ligand H-poa-ser-gly-phe-leu-thr-oh... 5 12
Melanocortin receptor 3 and Melanocortin receptor 4 Ligand C[c... 20 18
Angiotensin-converting enzyme and Endothelin-converting enzyme... 2 10
Type-1 angiotensin II receptor Ligand [sar1,tdf3]angii Family 135 2
cAMP-specific 3',5'-cyclic phosphodiesterase 4A and cAMP-speci... 3 29
Endothelin B receptor Ligand IRL-2500 Family 34 87
Vasopressin V1a receptor and Vasopressin V1b receptor Ligand D... 10 19
Gamma-aminobutyric acid receptor subunit alpha-1 and Gamma-ami... 12 72
Delta-type opioid receptor and Mu-type opioid receptor Ligand ... 18 72
Melanocortin receptor Ligand Ac-his-dphe(3,4-dicl)-arg-trp-nh2... 10 14
Somatostatin receptor type 1 and Somatostatin receptor type 2 ... 46 0
Bombesin receptor subtype-3 and Gastrin-releasing peptide rece... 42 7
Pol polyprotein inhibitor penicillin deriv. 71 family 1 2
Pol polyprotein inhibitor pyridin-2-ylmethyl N-[(2R)-1-[[(2S,3... 15 8
Cholecystokinin receptor type A ligand A-65186 family 2 6
Pol polyprotein inhibitor N-[(2S)-1-[[(2S,3R,4S,5S)-3,4-dihydr... 2 0
Cholecystokinin receptor type A and Gastrin/cholecystokinin ty... 17 28
Neutrophil collagenase and Stromelysin-3 inhibitor AC1MORIH fa... 7 9
Growth hormone secretagogue receptor type 1 ligand 2-amino-N-[... 3 0
Substance-P receptor ligand N-[(1S,2R)-2-[[(1R)-1-[methyl-(2-p... 2 0
Caspase-1 inhibitor (3S)-3-[[(2S)-4-[2-(1,2-dimethylindol-3-yl... 3 4
Caspase-1 inhibitor (3S)-4-oxo-3-[[(2S)-4-oxo-2-propan-2-yl-4-... 3 0
Prothrombin inhibitor (2S)-N-[(6-carbamimidoylpyridin-3-yl)met... 2 14
Somatostatin receptor type 2 ligand tert-butyl (2S)-6-amino-2-... 1 2
Cholecystokinin receptor type A and Gastrin/cholecystokinin ty... 4 53
Gastrin/cholecystokinin type B receptor and Cholecystokinin re... 2 0
Growth hormone-releasing hormone receptor ligand ethyl (1S)-1'... 3 2
Somatostatin receptor type 2 ligand (2R,3S)-N-[(5-amino-1,3-di... 2 5
Survival motor neuron protein and Menin inhibitor CHEMBL151109... 1 11
Gastrin/cholecystokinin type B receptor and Cholecystokinin re... 3 0
72 kDa type IV collagenase and Matrix metalloproteinase-9 inhi... 2 4
Pol polyprotein inhibitor (2S,4S,5S)-5-acetamido-6-cyclohexyl-... 3 3
Interstitial collagenase and Matrilysin inhibitor (2S,3R)-N,2-... 3 1
Relaxin-3 receptor 1 and Relaxin-3 receptor 2 ligand CHEMBL203... 4 1
KiSS-1 receptor ligand (2S)-N-[(2S)-1-[[(2S)-4-amino-1-[[(2S)-... 3 0
Pancreatic alpha-amylase and Gastrin/cholecystokinin type B re... 7 1
Gastrin/cholecystokinin type B receptor and Cholecystokinin re... 2 4
Mu-type opioid receptor and Delta-type opioid receptor ligand ... 1 0
Neprilysin and Angiotensin-converting enzyme inhibitor (2S)-2-... 1 4
Renin inhibitor tert-butyl N-[1-[[1-[[1-cyclohexyl-4,4-difluor... 5 0
Proteinase-activated receptor 1 and Prothrombin ligand (2S)-N-... 3 23
Endothelin B receptor and Endothelin-1 receptor ligand 2-[[(2R... 17 10
Neutrophil collagenase and Stromelysin-3 inhibitor [3-[[1-amin... 3 2
Growth factor receptor-bound protein 2 ligand 2-[4-[(2S)-3-[[1... 1 0
Substance-P receptor ligand (4R)-N-[(2R)-1-[benzyl(methyl)amin... 8 5
Bombesin receptor subtype-3 ligand SureCN13887096 family 3 1
Endothelin-1 receptor and Endothelin B receptor ligand 2-[[(2R... 5 3
Neuromedin-B receptor and Gastrin-releasing peptide receptor l... 6 4
Renin inhibitor (2R)-2-benzyl-N-[(2S)-1-[[(2S,3R,4S)-1-cyclohe... 6 0
Cholecystokinin receptor type A and Gastrin/cholecystokinin ty... 2 2
Somatostatin receptor type 2 ligand tert-butyl (2S)-6-amino-2-... 3 1
Growth factor receptor-bound protein 2 ligand [4-[(2S)-2-aceta... 5 2
KiSS-1 receptor ligand SureCN5132924 family 2 4
Angiotensin-converting enzyme inhibitor AC1L1IZN family 2 2
KiSS-1 receptor ligand N-[(2S)-1-[[2-[[(2S)-1-[[(2S)-1-[[(2S)-... 1 0
Interstitial collagenase and Stromelysin-1 inhibitor CHEMBL887... 1 0
E3 ubiquitin-protein ligase Mdm2 and Protein Mdm4 inhibitor CH... 2 1
Melanocortin receptor 4 and Melanocortin receptor 5 ligand CHE... 1 1


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00167237 DNCL002079 Clinical Trial Drug CBP-501
CFAMM00167241 DNC014105 Investigative Drug FGGFTGARKSARKWKNQ
CFAMM00167240 DNC014104 Investigative Drug FGGFTGARKSARKWRNQ
CFAMM00167231 DNC013943 Investigative Drug FGGFTGARKSARKWANQ
CFAMM00167236 DNC013950 Investigative Drug FGGFTGARKSARKLWNQ
CFAMM00167243 DNC014107 Investigative Drug FGGFTGARKSARKKWNQ
CFAMM00167242 DNC014106 Investigative Drug FGGFTGARKSARKRWNQ

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

24337 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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