CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFCD662
Family Name Iofolastat I-124 family
No. of Seeds 6 No. of Other Members 33
Family Centroid CFAMM00167726 Functional Category Clinical Trial Drug
Superfamily Iofolastat I-124 Superfamily
Class Class 1231

Cousin Family NamesSeedsMembers
Angiotensin-converting enzyme inhibitor Dicarboxylate-containi... 16 374
Angiotensin-converting enzyme inhibitor Dicarboxylate-containi... 7 54
ATP-sensitive inward rectifier potassium channel 10 Ligand Nat... 3 233
Bacterial outer membrane Inhibitor Polymyxin B Family 17 181
Neprilysin Inhibitor Thiorphan Family 41 68
Cathepsin F and Cruzipain Inhibitor WRR-99 Family 13 131
Thymidylate synthase Inhibitor Sp-876 Family 7 117
Penicillin-binding protein 1B Inhibitor N-benzoyl-d-alanine Fa... 1 40
Beta-secretase 1 Inhibitor Glu-leu-asp-leu-(choh-ch2)-ala-ala-... 15 11
Trifunctional purine biosynthetic protein adenosine-3 Inhibito... 2 11
Delta-type opioid receptor and Kappa-type opioid receptor Liga... 6 24
Delta-type opioid receptor and Kappa-type opioid receptor Liga... 3 21
Histone deacetylase 1 and Histone deacetylase 4 Inhibitor Azum... 3 10
DNA (cytosine-5)-methyltransferase 3B Inhibitor NSC-137546 Family 1 3
Genome polyprotein Inhibitor Acdif-ile-cha-cys Family 37 96
Cholecystokinin receptor type A Ligand CR-1795 Family 19 41
Tryptase alpha/beta-1 and Tryptase delta inhibitor (2S,3R)-1-b... 3 4
Glutamate receptor ionotropic, kainate 2 ligand (2S,3S,4S)-4-[... 14 2
Mitogen-activated protein kinase 14 and Cytochrome P450 2C9 in... 2 0
Glutamate carboxypeptidase 2 inhibitor (2S)-2-[[(1R)-1-carboxy... 8 0
Neprilysin inhibitor SureCN7437961 family 2 6
4-methyl-2-[[(E)-3-phenylprop-2-enyl]azaniumyl]pentanoate NP 2... 4 6


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00167740 CHEMBL595408 Bioactive (2S)-2-[[(1S)-1-carboxybut-3-ynyl]carbamoylamino]-6-[(4-iodobenzoyl)amino]hexanoic acid
CFAMM00167716 CHEMBL454897 Bioactive (2S)-2-[[(1S)-1-carboxy-5-[(4-fluorobenzoyl)amino]pentyl]carbamoylamino]pentanedioic acid
CFAMM00167745 CHEMBL495511 Bioactive SureCN4674080
CFAMM00167713 CHEMBL510924 Bioactive SureCN4673769
CFAMM00167748 CHEMBL298530 Bioactive (2S)-2-[[(S)-carboxy(phenyl)methyl]carbamoylamino]pentanedioic acid
CFAMM00167726 DNCL002153 Clinical Trial Drug Iofolastat I-124

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

27747 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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