CFam Chemical Families Database
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Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFCD665
Family Name RAC-gamma serine/threonine-protein kinase Inhibitor AZD5363 Family
No. of Seeds 35 No. of Other Members 69
Family Centroid CFAMM00167859 Functional Category Clinical Trial Drug with Natural Product
Superfamily RAC-gamma serine/threonine-protein kinase Inhibitor AZD5363 Superfamily
Class Class 1234

Cousin Family NamesSeedsMembers
Gamma-aminobutyric acid A receptor Ligand imidazopyridine deri... 5 644
Histamine H1 receptor Ligand Mizolastine Family 14 603
C-X-C chemokine receptor type 4 Ligand AMD-070 Family 12 800
Transient receptor potential cation channel subfamily V member... 16 295
Calcitonin gene-related peptide type 1 receptor Ligand Telcage... 25 124
Fibroblast growth factor receptor 2 and Fibroblast growth fact... 11 86
Cyclin-dependent kinase 4 Inhibitor PD-332991 Family 13 155
Cannabinoid receptor 1 Ligand AZD2207 Family 18 48
Cannabinoid receptor 1 Ligand CP-945598 Family 18 173
Mast/stem cell growth factor receptor Kit and Vascular endothe... 4 47
Translocator protein Inhibitor Emapunil Family 7 89
5-hydroxytryptamine receptor 1A and D(2) dopamine receptor Lig... 14 234
Adenosine receptor A1 Ligand SLV320 Family 6 79
Protein kinase C alpha type and Protein kinase C beta type Inh... 16 86
Aurora kinase B and Aurora kinase C Inhibitor GSK1070916 Family 53 580
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subun... 35 270
HCV NS4B protein Inhibitor Clemizole Family 2 43
RAC-gamma serine/threonine-protein kinase Inhibitor GDC-0068 F... 20 29
GDC-0349 family 44 77
Histone deacetylase 6 Inhibitor ACY-1215 Family 10 230
Vascular endothelial growth factor receptor 2 Ligand XL999 Family 11 87
Dipeptidyl peptidase 4 Inhibitor Nvp-dpp728 Family 11 42
Kappa-type opioid receptor Ligand Brl 52974 Family 2 27
Bacterial outer membrane Inhibitor HKI-9924129 Family 19 85
D(4) dopamine receptor Ligand L-745,870 Family 30 205
Histamine H3 receptor Ligand SCH79687 Family 11 29
Beta-secretase 1 Inhibitor 6-[2-(1h-indol-6-yl)ethyl]pyridin-2... 10 43
Adenosine receptor A3 Ligand 2,6-bis(4-chlorophenyl)-9h-purine... 4 12
Farnesyltransferase beta subunit, putative and Protein farnesy... 20 81
Serine/threonine-protein kinase B-raf Inhibitor 2-(benzylamino... 7 117
Epidermal growth factor receptor Ligand PD-158780 Family 98 89
D(2) dopamine receptor and D(3) dopamine receptor Ligand Azape... 7 102
Adenosine receptor A3 Ligand 1-benzyl-1h-1,3,4b,9-tetraaza-flu... 19 165
Cyclin-dependent kinase 1 Inhibitor CGP-60474 Family 14 103
Epidermal growth factor receptor Ligand N4-(3-chlorophenyl)qui... 7 39
5-hydroxytryptamine receptor 1A and 5-hydroxytryptamine recept... 19 103
RAC-gamma serine/threonine-protein kinase and Rho-associated p... 16 46
Adenosine receptor A3 Ligand 2-(5-chloro-1h-benzo[d]imidazol-2... 7 51
Melanocortin receptor Ligand Ac-his-dnal(2)-arg-trp-nh2 Family 112 67
Adenosine receptor A1 and Adenosine receptor A3 Ligand VUF-850... 28 47
Melanocortin receptor 3 and Melanocortin receptor 4 Ligand Ac-... 38 60
Proto-oncogene tyrosine-protein kinase Src Inhibitor BMS-27970... 41 59
Fatty-acid amide hydrolase 1 Inhibitor JNJ-1661010 Family 3 14
Aromatase and Cytochrome P450 26A1 Inhibitor Liarozole Family 4 1
RAF proto-oncogene serine/threonine-protein kinase Inhibitor L... 219 124
Glycogen synthase kinase-3 beta Inhibitor CHIR-98023 Family 5 6
Adenosine receptor A1 and Adenosine receptor A2a Ligand OSIP-3... 4 31
Bifunctional epoxide hydrolase 2 Inhibitor 6-amino-n-(2,4-dich... 10 116
Serine/threonine-protein kinase mTOR Inhibitor 4-(2-(1h-indol-... 2 15
Proto-oncogene tyrosine-protein kinase Src Inhibitor CGP-62464... 3 10
Sodium-dependent serotonin transporter Inhibitor 6-chloro-2-pi... 5 35
Proto-oncogene tyrosine-protein kinase Src Inhibitor 5,7-diphe... 2 11
Sodium channel protein type 1 subunit alpha and Sodium channel... 10 14
Metabotropic glutamate receptor 5 Ligand 2-(3,5-dichlorophenyl... 2 3
Delta-type opioid receptor and Mu-type opioid receptor Ligand ... 13 15
Acetylcholinesterase Inhibitor N-benzyl-2-morpholinopyrimidin-... 6 16
Melanocortin receptor Ligand Ac-his-dphe(3,4-dicl)-arg-trp-nh2... 10 14
Bombesin receptor subtype-3 and Gastrin-releasing peptide rece... 42 7
Cannabinoid receptor 1 Ligand 1-(4-chlorophenyl)-2-(2,4-dichlo... 18 41
Cannabinoid receptor 1 and Cannabinoid receptor 2 Ligand 6-(4-... 3 6
Prothrombin and Cationic trypsin inhibitor (2S)-N-[(2S)-1-(1H-... 4 15
5-hydroxytryptamine receptor 1F and 5-hydroxytryptamine recept... 8 12
Prothrombin inhibitor SureCN5856722 family 3 16
Tyrosine-protein kinase Lck and Tyrosine-protein kinase HCK in... 8 7
Mu-type opioid receptor and Mu-type opioid receptor ligand Sur... 5 10
Serine/threonine-protein kinase mTOR and Phosphatidylinositol ... 10 3
Adenosine receptor A3 ligand AGN-PC-07N4XX family 6 10
Aurora kinase B inhibitor AGN-PC-07ZZ0Y family 2 12
Serine/threonine-protein kinase mTOR and Phosphatidylinositol ... 2 12
Serine/threonine-protein kinase mTOR and Phosphatidylinositol ... 7 1
Tyrosine-protein kinase BTK and Tyrosine-protein kinase Lyn in... 7 7
Platelet-activating factor receptor ligand SureCN9523843 family 4 4
Platelet-activating factor receptor ligand SureCN9384429 family 11 3
RAC-alpha serine/threonine-protein kinase inhibitor SureCN4728... 11 6
Macrophage colony-stimulating factor 1 receptor and Cytochrome... 13 3
Mitogen-activated protein kinase 14 and Mitogen-activated prot... 2 21
RAF proto-oncogene serine/threonine-protein kinase and Serine/... 3 5
Adenosine kinase inhibitor 5-(4-chlorophenyl)-6-[2-(6-morpholi... 8 8
Dipeptidyl peptidase 4 and Dipeptidyl peptidase 9 inhibitor AG... 5 4
Dipeptidyl peptidase 9 and Dipeptidyl peptidase 8 inhibitor Su... 16 5
Serine/threonine-protein kinase pim-2 and Serine/threonine-pro... 6 9
Histamine H3 receptor ligand 1-[1-[1-[(2-aminopyridin-4-yl)met... 16 9
Histamine H3 receptor and Cytochrome P450 3A4 ligand AGN-PC-08... 15 5
Melanin-concentrating hormone receptor 1 and Potassium voltage... 8 27
Gamma-aminobutyric acid receptor subunit pi and GABA theta sub... 7 10
Cyclin-dependent kinase 5 and Cyclin-dependent kinase 1 inhibi... 2 0
RAC-alpha serine/threonine-protein kinase and Proline-rich AKT... 2 4
RAC-alpha serine/threonine-protein kinase inhibitor (2S)-3-ami... 2 0
Lysosomal Pro-X carboxypeptidase inhibitor 2-amino-N-[(2S)-1-[... 11 16
Cell division cycle 7-related protein kinase and Cyclin-depend... 2 9
P2X purinoceptor 7 inhibitor (4S)-N-[[2-chloro-3-(trifluoromet... 9 31
P2X purinoceptor 7 inhibitor (4S)-N-[[2-chloro-3-(trifluoromet... 5 3
C-C chemokine receptor type 5 ligand SureCN1573831 family 4 3
Peroxisome proliferator-activated receptor gamma ligand 1-[(4-... 7 29
Tyrosine-protein kinase JAK2 inhibitor N-[2-(3-chlorophenyl)-5... 2 11
Epidermal growth factor receptor ligand N-[4-(3-chloro-4-fluor... 8 4
Prelamin-A/C and Lethal(3)malignant brain tumor-like protein 1... 1 1
Prothrombin and Survival motor neuron protein inhibitor CHEMBL... 2 14
Dihydrofolate reductase and Bifunctional dihydrofolate reducta... 5 0
Dihydrofolate reductase inhibitor 6-[[(4-chloronaphthalen-1-yl... 2 1
Gonadotropin-releasing hormone receptor ligand 1-(7-azabicyclo... 4 4
Tyrosine-protein kinase JAK3 inhibitor N-methyl-N-[(1S,5S)-2-m... 2 12
RAC-alpha serine/threonine-protein kinase inhibitor 2-[(4-chlo... 11 2
Prothrombin and Trypsin-1 inhibitor 2-[6-methyl-2-oxo-3-(2-pyr... 4 2
Cannabinoid receptor 2 and Cannabinoid receptor 1 ligand AGN-P... 5 0
C-C chemokine receptor type 5 and Potassium voltage-gated chan... 21 32
Ceramide glucosyltransferase inhibitor AGN-PC-07YS0C family 4 3
Bile acid receptor and Potassium voltage-gated channel subfami... 2 1
C-X-C chemokine receptor type 3 ligand SureCN13205646 family 4 0
Tyrosine-protein kinase JAK2 inhibitor AGN-PC-09QM1E family 8 15
Toll-like receptor 7 ligand 6-amino-2-(butylamino)-9-[[4-(dime... 5 4
Cannabinoid receptor 1 and Cannabinoid receptor 2 ligand SureC... 6 14
Cannabinoid receptor 1 and Cannabinoid receptor 2 ligand AGN-P... 2 0
Signal transducer and activator of transcription 6 inhibitor A... 3 0
Serine/threonine-protein kinase mTOR and Phosphatidylinositol ... 3 0
MAP kinase-activated protein kinase 2 inhibitor AGN-PC-0A9QGC ... 14 0
D(3) dopamine receptor and D(2) dopamine receptor ligand N-[(E... 1 0
Nociceptin receptor and Potassium voltage-gated channel subfam... 10 1
Histone deacetylase 1 inhibitor (E)-N-hydroxy-3-[4-[[2-(1H-pyr... 2 8
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subun... 2 0
Sodium-dependent serotonin transporter and 5-hydroxytryptamine... 5 8
Coagulation factor X and Prothrombin inhibitor 2-carboxyindole... 2 8
Tyrosine-protein kinase JAK2 and Tyrosine-protein kinase JAK3 ... 14 2
Tyrosine-protein kinase JAK1 inhibitor CHEMBL2206623 family 10 11
Coagulation factor X inhibitor SureCN8289965 family 4 5
Bifunctional epoxide hydrolase 2 inhibitor AGN-PC-0733AC family 7 29
Melanin-concentrating hormone receptor 1 ligand AGN-PC-075X3N ... 1 7
Serine/threonine-protein kinase mTOR inhibitor 5-(2-amino-3H-b... 3 1
Lysosomal Pro-X carboxypeptidase inhibitor methyl N-[4-[[6-[[(... 1 1
Cell division cycle 7-related protein kinase and Protein DBF4 ... 15 7
Cell division cycle 7-related protein kinase and Dual specific... 3 1
Aurora kinase B and Aurora kinase A inhibitor 4-amino-N-[3-[[(... 5 3
Protein kinase C theta type and Leucine-rich repeat serine/thr... 1 1
Histamine H3 receptor ligand 1-[4-(1H-imidazol-5-ylmethyl)pipe... 1 2
Vascular endothelial growth factor receptor 2 ligand (3Z)-3-[5... 4 11
C-C chemokine receptor type 4 ligand [4-[4-[(2,4-dichloropheny... 4 4
Epidermal growth factor receptor and Receptor tyrosine-protein... 8 4
Melanin-concentrating hormone receptor 1 and 5-hydroxytryptami... 2 0
Glycogen synthase kinase-3 beta inhibitor N-[2-[4-(ethylsulfon... 3 1
Glycogen synthase kinase-3 beta inhibitor 2-(4-fluorophenyl)-N... 4 2
Glycogen synthase kinase-3 beta inhibitor 2-(4-fluorophenyl)-N... 7 3
Cannabinoid receptor 2 ligand 8-(2-chlorophenyl)-9-cyclopropyl... 4 5
Corticotropin-releasing factor receptor 1 ligand 4-[(1R)-1-cyc... 5 6
Translocator protein inhibitor N-butan-2-yl-4-(2-chlorophenyl)... 14 12
Dipeptidyl peptidase 4 inhibitor [(2S,4S)-4-(4-isoquinolin-1-y... 3 2
Lysine--tRNA ligase inhibitor N-[2-(2-piperazin-1-ylpyridin-4-... 5 0
Somatostatin receptor type 3 ligand tert-butyl 4-[(3R)-3-(5-ph... 2 2
Mitogen-activated protein kinase 14 inhibitor pyrimido-pyrimid... 15 0
C-C chemokine receptor type 5 ligand AC1MHRXO family 5 1
Tyrosine-protein kinase Lck inhibitor AGN-PC-0762YG family 2 2
Renin inhibitor AGN-PC-073MLF family 7 6
Aurora kinase A and Cyclin-dependent kinase 4 inhibitor 7-cycl... 1 0
Succinate receptor 1 ligand N-[[4-(3-methylphenyl)phenyl]methy... 2 14
Substance-P receptor ligand SureCN7659714 family 2 0
Cathepsin K inhibitor CHEMBL2163360 family 1 0
Tyrosine-protein kinase JAK2 inhibitor N-[3-(3-chlorophenyl)-1... 12 4
RAC-alpha serine/threonine-protein kinase and RAC-gamma serine... 2 0
Cannabinoid receptor 1 and Cannabinoid receptor 2 ligand N-[1-... 5 3
Cathepsin K and Cathepsin S inhibitor 2-Cyano-pyrimidine, 17d ... 5 9
Receptor-type tyrosine-protein kinase FLT3 and Aurora kinase A... 2 0
P2X purinoceptor 7 inhibitor SureCN109432 family 10 28
P2X purinoceptor 7 inhibitor SureCN9931311 family 2 0
P2X purinoceptor 7 inhibitor (4S)-N-[(2,4-dichlorophenyl)methy... 6 3
P2X purinoceptor 7 inhibitor SureCN1635928 family 4 4
P2X purinoceptor 7 inhibitor (4S)-N-[(2,4-dichlorophenyl)methy... 1 2
P2X purinoceptor 7 inhibitor SureCN113576 family 2 1
Dipeptidyl peptidase 4 inhibitor (4R,5R)-5-amino-1-[6-(3-methy... 2 5
Corticosteroid 11-beta-dehydrogenase isozyme 1 inhibitor (4-am... 2 1
Adenosine kinase inhibitor 4-[2-[5-(4-chlorophenyl)-6-piperazi... 3 1
Cannabinoid receptor 1 and Cannabinoid receptor 2 ligand SureC... 6 5
Corticotropin-releasing factor receptor 1 and Corticotropin-re... 6 3
Fatty-acid amide hydrolase 1 inhibitor 4-(3-phenyl-1,2,4-thiad... 2 1
CGMP-dependent protein kinase inhibitor SureCN14561191 family 4 0
Corticotropin-releasing factor receptor 1 and Corticotropin-re... 5 2
Tyrosine-protein kinase SYK inhibitor N-tert-butyl-2-(6-fluoro... 5 1
Orexin receptor type 2 and Orexin receptor type 1 ligand (2R)-... 12 16
Dipeptidyl peptidase 4 and Cytochrome P450 2D6 inhibitor (3R)-... 4 12
Tyrosine-protein kinase SYK inhibitor N-tert-butyl-2-(6-chloro... 2 0
Tyrosine-protein kinase JAK3 and Tyrosine-protein kinase JAK2 ... 12 3
Non-receptor tyrosine-protein kinase TYK2 ligand AGN-PC-0D0YSZ... 10 0
Non-receptor tyrosine-protein kinase TYK2 ligand SureCN1298914... 3 0
Histone deacetylase 1 and Proto-oncogene tyrosine-protein kina... 4 0
Calcitonin gene-related peptide type 1 receptor ligand N-[2-(7... 16 0
Orexin receptor type 2 and Orexin receptor type 1 ligand 9-(4,... 2 8
Eukaryotic translation initiation factor 2-alpha kinase 3 and ... 4 0
cAMP-specific 3',5'-cyclic phosphodiesterase 4B inhibitor 4-[4... 1 1
Histone deacetylase 1 inhibitor 1-methyl-N-[(1S)-7-oxo-1-(5-qu... 2 3
Histone deacetylase 1 inhibitor 1-methyl-N-[(1S)-7-oxo-1-(5-qu... 2 1
Cathepsin K inhibitor SureCN4138062 family 7 0
Cathepsin K and Cathepsin S inhibitor SureCN4138353 family 3 0
Mitogen-activated protein kinase 10 inhibitor CYCLOPROPYL-{4-[... 2 1
RAF proto-oncogene serine/threonine-protein kinase and Serine/... 4 3
Nociceptin receptor and Potassium voltage-gated channel subfam... 5 2
LIM domain kinase 2 inhibitor (2S)-N-cyano-N'-(3-cyanophenyl)-... 4 0
Mitogen-activated protein kinase 14 inhibitor 5-[2-(2,6-dichlo... 1 0
D(4) dopamine receptor and D(3) dopamine receptor ligand SureC... 1 0
Matrilysin and Stromelysin-1 inhibitor (2R)-N-[(1S)-1-(1H-benz... 3 0
Epidermal growth factor receptor and Receptor tyrosine-protein... 5 8
Substance-K receptor ligand SureCN9035669 family 10 5
Alpha-1A adrenergic receptor and Alpha-1D adrenergic receptor ... 2 0
Alpha-1B adrenergic receptor and Alpha-1D adrenergic receptor ... 1 0
Tripeptidyl-peptidase 2 inhibitor (2S)-2-amino-1-[(2S)-5-chlor... 1 0
Coagulation factor X inhibitor SureCN1652469 family 2 1
Nitric oxide synthase, inducible inhibitor N-[(4-chlorophenyl)... 2 1
Nociceptin receptor and Mu-type opioid receptor ligand SureCN5... 1 0
Serine/threonine-protein kinase B-raf inhibitor 1-[2-[[4-[2-cy... 2 0
Corticotropin-releasing factor receptor 1 and Corticotropin-re... 2 1
Proto-oncogene tyrosine-protein kinase Src and Fibroblast grow... 3 4
Gonadotropin-releasing hormone receptor ligand SureCN3275214 f... 5 0
Epidermal growth factor receptor ligand (E)-5-[4-(3-bromoanili... 11 0
Cyclin-dependent kinase 2 and Potassium voltage-gated channel ... 12 7
Cannabinoid receptor 1 and Cannabinoid receptor 2 ligand SureC... 7 0
RAC-alpha serine/threonine-protein kinase and RAC-gamma serine... 20 7
Cell division cycle 7-related protein kinase and Cyclin-depend... 2 0
P2X purinoceptor 7 inhibitor N-[1-[(Z)-[(cyanoamino)-(quinolin... 3 3
Neuropeptide Y receptor type 5 ligand 1-methylsulfonyl-N-(2-ph... 4 0
Cannabinoid receptor 1 ligand AGN-PC-077JWI family 7 1
Bifunctional epoxide hydrolase 2 and Potassium voltage-gated c... 1 0
Nociceptin receptor and Mu-type opioid receptor ligand (1S,5S)... 1 0
Tyrosine-protein kinase Lck inhibitor (3S)-3-[(1S)-1-[[4-(benz... 14 0
LIM domain kinase 1 and LIM domain kinase 2 inhibitor (2S)-N'-... 9 0
Melanin-concentrating hormone receptor 1 and Alpha-2A adrenerg... 1 0
LIM domain kinase 2 inhibitor 3-[[(cyanoamino)-[(2S)-2-methyl-... 6 0
Poly [ADP-ribose] polymerase 1 and Poly [ADP-ribose] polymeras... 4 0
Poly [ADP-ribose] polymerase 1 inhibitor AGN-PC-07R96X family 7 1
Cannabinoid receptor 1 ligand AGN-PC-07R6O8 family 5 2
RAC-alpha serine/threonine-protein kinase and RAC-beta serine/... 1 0
Melanocortin receptor 4 ligand (3R)-N-[(2R)-3-(4-chlorophenyl)... 2 0
P2X purinoceptor 7 inhibitor N-[(3-chloro-2-methylphenyl)methy... 7 0
Inosine-5'-monophosphate dehydrogenase inhibitor N-(4-chloroph... 1 2
Melanin-concentrating hormone receptor 1 ligand (E)-3-(4-chlor... 3 7
Melanin-concentrating hormone receptor 1 ligand (E)-3-(4-chlor... 6 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00167869 CHEMBL2325993 Bioactive 4-amino-N-[1-(4-chlorophenyl)-4-(dimethylamino)butyl]-1-(7H-pyrrolo[2,3-d]pyrimidin-4-yl)piperidine-4-carboxamide
CFAMM00167835 CHEMBL2325743 Bioactive 4-amino-N-[(1S)-1-(4-chlorophenyl)ethyl]-1-(7H-pyrrolo[2,3-d]pyrimidin-4-yl)piperidine-4-carboxamide
CFAMM00167848 CHEMBL2325983 Bioactive 4-amino-N-[(4-chlorophenyl)-cyclopropylmethyl]-1-(7H-pyrrolo[2,3-d]pyrimidin-4-yl)piperidine-4-carboxamide
CFAMM00167876 CHEMBL2325727 Bioactive 4-amino-N-[(1S)-1-(4-chlorophenyl)-3-(dimethylamino)propyl]-1-(7H-pyrrolo[2,3-d]pyrimidin-4-yl)piperidine-4-carboxamide
CFAMM00167891 CHEMBL2325734 Bioactive 4-amino-N-[1-(4-chlorophenyl)-3-sulfamoylpropyl]-1-(7H-pyrrolo[2,3-d]pyrimidin-4-yl)piperidine-4-carboxamide
CFAMM00167920 CHEMBL1258331 Bioactive SureCN13229961
CFAMM00167868 CHEMBL2325992 Bioactive 4-amino-N-[1-(4-chlorophenyl)-3-(dimethylamino)propyl]-1-(7H-pyrrolo[2,3-d]pyrimidin-4-yl)piperidine-4-carboxamide
CFAMM00167847 CHEMBL604507 Bioactive AGN-PC-07B2KX
CFAMM00167911 CHEMBL1257402 Bioactive (2S)-3-amino-2-(4-chlorophenyl)-1-[4-(7H-pyrrolo[2,3-d]pyrimidin-4-yl)piperazin-1-yl]propan-1-one
CFAMM00167890 CHEMBL2325737 Bioactive 4-amino-N-[1-(4-chlorophenyl)-2-hydroxyethyl]-1-(7H-pyrrolo[2,3-d]pyrimidin-4-yl)piperidine-4-carboxamide
CFAMM00167867 CHEMBL2325995 Bioactive 4-amino-N-[1-(4-chlorophenyl)-4-morpholin-4-ylbutyl]-1-(7H-pyrrolo[2,3-d]pyrimidin-4-yl)piperidine-4-carboxamide
CFAMM00167926 CHEMBL604910 Bioactive SureCN1003771
CFAMM00167860 CHEMBL597803 Bioactive AGN-PC-07B2KZ
CFAMM00167889 CHEMBL2325736 Bioactive 4-amino-N-[1-(4-chlorophenyl)-3-(methanesulfonamido)propyl]-1-(7H-pyrrolo[2,3-d]pyrimidin-4-yl)piperidine-4-carboxamide
CFAMM00167826 CHEMBL598206 Bioactive AGN-PC-07B2KV
CFAMM00167852 CHEMBL1258664 Bioactive (2R)-2-amino-3-(4-chlorophenyl)-1-[4-(5-methyl-7H-pyrrolo[2,3-d]pyrimidin-4-yl)piperazin-1-yl]propan-1-one
CFAMM00167866 CHEMBL2325994 Bioactive 4-amino-N-[1-(4-chlorophenyl)-4-pyrrolidin-1-ylbutyl]-1-(7H-pyrrolo[2,3-d]pyrimidin-4-yl)piperidine-4-carboxamide
CFAMM00167935 CHEMBL1258552 Bioactive (2R)-2-amino-3-(4-chlorophenyl)-1-[4-(7H-pyrrolo[2,3-d]pyrimidin-4-yl)piperazin-1-yl]propan-1-one
CFAMM00167888 CHEMBL598194 Bioactive AGN-PC-00DWNO
CFAMM00167851 CHEMBL1258665 Bioactive (2R)-2-amino-3-(4-chlorophenyl)-1-[4-(5-ethyl-7H-pyrrolo[2,3-d]pyrimidin-4-yl)piperazin-1-yl]propan-1-one
CFAMM00167825 CHEMBL1236822 Bioactive SureCN13229976
CFAMM00167865 CHEMBL2325997 Bioactive SureCN387281
CFAMM00167879 CHEMBL2325728 Bioactive 4-amino-N-[(1S)-1-(4-chlorophenyl)-3-pyrrolidin-1-ylpropyl]-1-(7H-pyrrolo[2,3-d]pyrimidin-4-yl)piperidine-4-carboxamide
CFAMM00167831 CHEMBL599849 Bioactive AGN-PC-07B2KU
CFAMM00167924 CHEMBL1258780 Bioactive (2R)-2-amino-3-(4-chlorophenyl)-1-[4-(5-cyclopropyl-7H-pyrrolo[2,3-d]pyrimidin-4-yl)piperazin-1-yl]propan-1-one
CFAMM00167837 CHEMBL2325740 Bioactive 4-amino-N-[1-(4-chlorophenyl)-3-methoxypropyl]-1-(7H-pyrrolo[2,3-d]pyrimidin-4-yl)piperidine-4-carboxamide
CFAMM00167850 CHEMBL597600 Bioactive AGN-PC-07B2KY
CFAMM00167878 CHEMBL2325729 Bioactive 4-amino-N-[(1S)-1-(4-chlorophenyl)-3-piperidin-1-ylpropyl]-1-(7H-pyrrolo[2,3-d]pyrimidin-4-yl)piperidine-4-carboxamide
CFAMM00167864 CHEMBL2325996 Bioactive 4-amino-N-[1-(4-chlorophenyl)-4-piperidin-1-ylbutyl]-1-(7H-pyrrolo[2,3-d]pyrimidin-4-yl)piperidine-4-carboxamide
CFAMM00167923 CHEMBL1258781 Bioactive (2R)-2-amino-3-(4-chlorophenyl)-1-[4-(5-chloro-7H-pyrrolo[2,3-d]pyrimidin-4-yl)piperazin-1-yl]propan-1-one
CFAMM00167849 CHEMBL2325982 Bioactive 4-amino-N-[1-(4-chlorophenyl)propyl]-1-(7H-pyrrolo[2,3-d]pyrimidin-4-yl)piperidine-4-carboxamide
CFAMM00167859 DNCL002159 Clinical Trial Drug AZD5363

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

24631 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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