CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

Family Name Fibroblast growth factor receptor 1 Ligand BGJ398 Family
No. of Seeds 3 No. of Other Members 6
Family Centroid CFAMM00167937 Functional Category Clinical Trial Drug
Superfamily Fibroblast growth factor receptor 1 Ligand BGJ398 Superfamily
Class Class 1049

Cousin Family NamesSeedsMembers
Proto-oncogene tyrosine-protein kinase Src Inhibitor PD166285 ... 6 70


External ID

Functional Category

Molecule Name

CFAMM00167945 CHEMBL2216830 Bioactive N-[3-[[3-(2,6-dichloro-3,5-dimethoxyphenyl)-7-[4-(diethylamino)butylamino]-2-oxo-4H-pyrimido[4,5-d]pyrimidin-1-yl]methyl]phenyl]prop-2-enamide
CFAMM00167942 CHEMBL1834657 Bioactive 3-(2,6-dichloro-3,5-dimethoxyphenyl)-1-[6-[4-(4-ethylpiperazin-1-yl)anilino]pyrimidin-4-yl]-1-methylurea;phosphoric acid
CFAMM00167937 DNCL002160 Clinical Trial Drug BGJ398

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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