CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFCD674
Family Name CPI-613 family
No. of Seeds 4 No. of Other Members 35
Family Centroid CFAMM00168176 Functional Category Clinical Trial Drug
Superfamily Aldose reductase Inhibitor Sulindac Superfamily
Class Class 340

Cousin Family NamesSeedsMembers
Cyclooxygenase Inhibitor Flurbiprofen Family 18 294
Prostaglandin G/H synthase 2 Inhibitor Ketoprofen Family 5 84
Prostaglandin G/H synthase 1 Inhibitor Suprofen Family 4 52
Dihydroorotate dehydrogenase Inhibitor Polyporic Acid Family 4 13
Proto-oncogene tyrosine-protein kinase Src Inhibitor RU79256 F... 1 0
Carboxypeptidase B2 Inhibitor Dl-benzylsuccinic Acid Family 1 11
C-X-C chemokine receptor type 1 and C-X-C chemokine receptor t... 2 53
72 kDa type IV collagenase and Macrophage metalloelastase Inhi... 2 5
Glutamate carboxypeptidase 2 Inhibitor 2-(3-cyanobenzyl)-5-mer... 1 0
Glutamate carboxypeptidase 2 Inhibitor 3-(2-carboxy-6-mercapto... 9 4
Collagenase 3 and Macrophage metalloelastase Inhibitor 5-(4'-c... 4 43
Macrophage metalloelastase Inhibitor 2-(2-(biphenyl-4-yl)ethyl... 3 11
Prostaglandin G/H synthase 1 Inhibitor 2-(3'-ethylsulfanyl-bip... 1 4
Trypsin-1 and Prothrombin inhibitor (3S,3aR,6aS)-3-benzyl-3,3a... 2 23
Cysteinyl leukotriene receptor 1 ligand POBILUKAST family 2 4
Corticosteroid 11-beta-dehydrogenase isozyme 1 inhibitor 2-[9-... 2 15
Transporter and Sodium-dependent serotonin transporter inhibit... 3 5
Transporter and Sodium-dependent serotonin transporter inhibit... 2 5
Glutamate carboxypeptidase 2 inhibitor SureCN5052894 family 1 17
Leukotriene B4 receptor 1 ligand 2,2-dimethyl-7-[3-(3-phenylpr... 2 10
Retinal dehydrogenase 1 and Microtubule-associated protein tau... 1 7
Cysteinyl leukotriene receptor 1 and Cysteinyl leukotriene rec... 6 0
Sodium-dependent dopamine transporter inhibitor AGN-PC-074TA8 ... 2 5
Neprilysin and Angiotensin-converting enzyme inhibitor 5-benzy... 1 2
Angiotensin-converting enzyme inhibitor AGN-PC-00NKX7 family 2 2
Carboxylic Acids and Derivatives Metabolite 3-Acetoxy-3-methyl... 2 0
Putative NP ZINC06763537 Family 6 4
7a-hydroxy-7-phenyl-3,3a,4,5,6,7-hexahydro-1-benzofuran-2-one ... 4 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00168176 DNCL002244 Clinical Trial Drug CPI-613
CFAMM00168177 DNC006512 Investigative Drug 2-benzyl-5-mercaptopentanoic acid
CFAMM00168196 DNC014794 Investigative Drug SQ-14603
CFAMM00168191 DNC002883 Investigative Drug 2-Thiomethyl-3-Phenylpropanoic Acid

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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