CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

Family Name TOK-001 family
No. of Seeds 2 No. of Other Members 7
Family Centroid CFAMM00168207 Functional Category Clinical Trial Drug
Superfamily TOK-001 Superfamily
Class Class 1238

Cousin Family NamesSeedsMembers
5-hydroxytryptamine receptor 1A and D(2) dopamine receptor Lig... 14 234
Adenosine receptor A1 Ligand SLV320 Family 6 79
C-Jun N-terminal kinase Inhibitor CC-930 Family 2 9
Glucan synthesis regulatory protein Inhibitor Pyridobenzimidaz... 2 12
Prostaglandin G/H synthase 2 Inhibitor RWJ-67657 Family 3 33
Metabotropic glutamate receptor 5 Ligand 3-(4-pyridin-2-yl-imi... 6 5
RAF proto-oncogene serine/threonine-protein kinase Inhibitor L... 219 124
Mitogen-activated protein kinase 8 and Mitogen-activated prote... 2 5
Mitogen-activated protein kinase 14 inhibitor AGN-PC-03XQYG fa... 7 1
Insulin-like growth factor 1 receptor ligand AGN-PC-09QIDN family 1 3
Adenosine deaminase inhibitor AGN-PC-00FYYU family 4 5
Gamma-aminobutyric acid receptor subunit gamma-2 and Gamma-ami... 11 3
Protein farnesyltransferase/geranylgeranyltransferase type-1 s... 2 1
Glucocorticoid receptor ligand SureCN12238714 family 16 4
Glucocorticoid receptor and Progesterone receptor ligand SureC... 6 1
Substance-P receptor ligand CHEMBL124542 family 3 4


External ID

Functional Category

Molecule Name

CFAMM00168208 CHEMBL566391 Bioactive AGN-PC-07CQM9
CFAMM00168207 DNCL002250 Clinical Trial Drug TOK-001

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

Last update by



55287 visits since 2014 .........


Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

All rights reserved.

Computer-aided Drug Design
about BIDD |  databases |  software |  teaching |  research |  links


Department of Computational Science | National University of Singapore | Blk S17, 3 Science Drive 2, Singapore 117543