CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFCD7
Family Name Cyclin-dependent kinase 2 and Cyclin-dependent kinase 7 Inhibitor SNS-032 Family
No. of Seeds 11 No. of Other Members 38
Family Centroid CFAMM00126897 Functional Category Clinical Trial Drug
Superfamily Cyclin-dependent kinase 2 and Cyclin-dependent kinase 7 Inhibitor SNS-032 Superfamily
Class Class 818

Cousin Family NamesSeedsMembers
G1/S-specific cyclin-E2 and Cyclin-dependent kinase 2 inhibito... 6 19
G1/S-specific cyclin-E2 and G1/S-specific cyclin-E1 inhibitor ... 3 1
G1/S-specific cyclin-E2 and G1/S-specific cyclin-E1 inhibitor ... 3 2
G1/S-specific cyclin-E2 and G1/S-specific cyclin-E1 inhibitor ... 1 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00126937 CHEMBL126993 Bioactive 2-amino-5-thio-substituted thiazole 46
CFAMM00126915 CHEMBL455195 Bioactive AGN-PC-078WFT
CFAMM00126905 CHEMBL496785 Bioactive AGN-PC-077MQ2
CFAMM00126896 CHEMBL495557 Bioactive AGN-PC-077MPH
CFAMM00126934 CHEMBL452602 Bioactive (3R,5S)-N-[5-[(5-tert-butyl-1,3-oxazol-2-yl)methylsulfanyl]-1,3-thiazol-2-yl]-5-methylpiperidine-3-carboxamide
CFAMM00126933 CHEMBL452601 Bioactive (3R,5R)-N-[5-[(5-tert-butyl-1,3-oxazol-2-yl)methylsulfanyl]-1,3-thiazol-2-yl]-5-methylpiperidine-3-carboxamide
CFAMM00126895 CHEMBL129471 Bioactive 2-amino-5-thio-substituted thiazole 24
CFAMM00126888 CHEMBL295136 Bioactive AC1NS7CD
CFAMM00126893 CHEMBL126328 Bioactive 2-amino-5-thio-substituted thiazole 26
CFAMM00126938 CHEMBL126630 Bioactive 2-amino-5-thio-substituted thiazole 29
CFAMM00126897 DCL000007 Clinical Trial Drug SNS-032

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

21768 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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