CFam Chemical Families Database
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Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFCD703
Family Name RAF proto-oncogene serine/threonine-protein kinase Inhibitor RAF265 Family
No. of Seeds 7 No. of Other Members 148
Family Centroid CFAMM00169134 Functional Category Clinical Trial Drug
Superfamily Fibroblast growth factor receptor 3 and RAF proto-oncogene serine/threonine-protein kinase Binder Superfamily
Class Class 975

Cousin Family NamesSeedsMembers
Serine/threonine-protein kinase B-raf inhibitor diaryl urea an... 12 93
Potassium-transporting ATPase alpha chain 1 Inhibitor Rabepraz... 4 113
Histamine H1 receptor Ligand Astemizole Family 7 240
Peptide deformylase, mitochondrial Inhibitor Trimetrexate Family 4 311
Epidermal growth factor receptor Ligand Gefitinib Family 26 600
Potassium-transporting ATPase alpha chain 1 Inhibitor Pantopra... 1 3
Corticotropin-releasing factor receptor 1 Ligand CRF-1 Antagon... 29 421
Receptor tyrosine-protein kinase erbB-2 Inhibitor CP-724714 Fa... 4 180
Platelet-derived growth factor receptor Ligand CP-868596 Family 3 91
Insulin-like growth factor 1 receptor Ligand AEW-541 Family 12 140
Abelson tyrosine-protein kinase 2 and Proto-oncogene tyrosine-... 25 40
Receptor tyrosine-protein kinase erbB-2 Inhibitor TAK-285 Family 16 124
Corticotropin-releasing factor receptor 1 Ligand GW876008 Family 3 30
AP26113 family 16 90
SB1518 family 7 103
Hepatocyte growth factor receptor Ligand Amg 208 Family 20 236
Protein kinase C theta type Inhibitor 4-(1h-indol-5-yloxy)-5-s... 21 194
DNA Binder Bisbenzimide (hoechst 33258) Family 4 159
Peptide deformylase, mitochondrial Inhibitor Epiroprim Family 5 68
Tyrosine kinase Inhibitor PKI166 Family 17 198
Heat shock protein HSP 90-alpha Inhibitor 8-benzo[1,3]dioxol-,... 5 83
Cyclin-dependent kinase 2 Inhibitor 6-cyclohexylmethyloxy-2-(4... 2 11
Angiopoietin-1 receptor and Tyrosine-protein kinase Lck Inhibi... 3 64
Methylated-DNA--protein-cysteine methyltransferase Inhibitor 6... 4 5
Cyclin-dependent kinase 2 and Cyclin-dependent kinase 9 Inhibi... 10 35
D(2) dopamine receptor and D(3) dopamine receptor Ligand [2-(1... 17 100
Glutamate receptor ionotropic, NMDA 2B and Glutamate receptor ... 3 23
Cytochrome P450 2D6 and Cytochrome P450 3A4 Inhibitor 2-[3-(4-... 7 128
Cyclin-dependent kinase 2 and Cyclin-dependent kinase 4 Inhibi... 19 48
Adenosine receptor A1 and Adenosine receptor A3 Ligand 2-(4-me... 3 23
Glycogen synthase kinase-3 beta and Mitogen-activated protein ... 8 8
D(4) dopamine receptor Ligand A-425444 Family 2 10
Adenosine receptor A1 and Adenosine receptor A2a Ligand 2-(3''... 2 3
Fatty-acid amide hydrolase 1 Inhibitor BMS-1 Family 5 22
Epidermal growth factor receptor Ligand 4-(5-bromoindole-3-yl)... 6 15
Platelet-derived growth factor receptor alpha and Platelet-der... 3 18
Reverse transcriptase Inhibitor UK-129485 Family 23 221
Delta-type opioid receptor and Kappa-type opioid receptor Liga... 10 46
Delta-type opioid receptor and Mu-type opioid receptor Ligand ... 18 72
cGMP-specific 3',5'-cyclic phosphodiesterase Inhibitor SK&F-96... 5 83
Dual specificity mitogen-activated protein kinase kinase 1 inh... 10 54
Cyclin-dependent kinase 2 and Cyclin-dependent kinase 1 inhibi... 2 22
Sodium-dependent serotonin transporter and 5-hydroxytryptamine... 3 4
Platelet-derived growth factor receptor beta and Platelet-deri... 2 19
Alpha-1B adrenergic receptor and Alpha-1D adrenergic receptor ... 6 35
Tyrosine-protein kinase Lck inhibitor 4-N-(2-chloro-6-methylph... 8 45
Serine/threonine-protein kinase B-raf inhibitor SureCN1015955 ... 17 18
Tyrosine-protein kinase JAK3 and Tyrosine-protein kinase JAK2 ... 2 6
Vascular endothelial growth factor receptor 2 and Angiopoietin... 2 11
Histamine H4 receptor ligand AGN-PC-07ZG9H family 4 4
Angiopoietin-1 receptor and Aurora kinase B ligand SureCN97387... 4 1
cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10... 6 11
Sphingosine 1-phosphate receptor 1 and Sphingosine 1-phosphate... 7 16
3-phosphoinositide-dependent protein kinase 1 and Ribosomal pr... 10 4
Hepatocyte growth factor receptor and Receptor-type tyrosine-p... 12 26
Adenosine receptor A3 ligand CHEMBL1834696 family 5 18
Beta-1 adrenergic receptor and Beta-2 adrenergic receptor liga... 4 18
Tyrosine-protein kinase Lck inhibitor AGN-PC-073GX8 family 12 1
Lysine--tRNA ligase and Dual specificity protein kinase CLK4 i... 4 27
cGMP-inhibited 3',5'-cyclic phosphodiesterase B and cGMP-inhib... 39 10
cGMP-inhibited 3',5'-cyclic phosphodiesterase B and cGMP-inhib... 7 5
Dipeptidyl peptidase 4 and Dipeptidyl peptidase 8 inhibitor Su... 2 16
Cathepsin S and Cathepsin K inhibitor SureCN1629664 family 10 11
Cathepsin S and Cathepsin K inhibitor AGN-PC-07YOWS family 4 6
Cathepsin S and Cathepsin K inhibitor AGN-PC-088VBO family 3 11
Gamma-aminobutyric acid receptor subunit gamma-2 and Gamma-ami... 31 11
Extracellular calcium-sensing receptor ligand SureCN2972008 fa... 4 1
Heat shock protein HSP 90-alpha inhibitor 3-[2-amino-4-chloro-... 7 2
5-hydroxytryptamine receptor 1D and 5-hydroxytryptamine recept... 9 19
Angiopoietin-1 receptor and Aurora kinase B ligand SureCN12658... 3 19
Vascular endothelial growth factor receptor 2 and Fibroblast g... 3 11
Vascular endothelial growth factor receptor 2 and Fibroblast g... 10 3
Vascular endothelial growth factor receptor 2 ligand AGN-PC-09... 5 11
Glucocorticoid receptor ligand (2R)-1,1,1-trifluoro-4-(2-metho... 2 5
Casein kinase I isoform delta and Mitogen-activated protein ki... 3 18
Neuropeptide Y receptor type 5 and Alpha-1A adrenergic recepto... 8 2
Adenosine receptor A2b and Adenosine receptor A1 ligand SureCN... 52 12
cGMP-specific 3',5'-cyclic phosphodiesterase inhibitor SureCN6... 19 11
cGMP-specific 3',5'-cyclic phosphodiesterase inhibitor SureCN6... 8 12
DNA-(apurinic or apyrimidinic site) lyase and Retinal dehydrog... 1 3
Survival motor neuron protein inhibitor CHEMBL1379159 family 1 10
Dihydrofolate reductase and Bifunctional dihydrofolate reducta... 3 10
Cellular tumor antigen p53 inhibitor CHEMBL1401545 family 1 25
D(3) dopamine receptor and D(2) dopamine receptor ligand AGN-P... 3 14
Thyroid hormone receptor beta and Ferritin light chain ligand ... 1 35
Cellular tumor antigen p53 and Prelamin-A/C inhibitor CHEMBL14... 2 11
D(3) dopamine receptor and D(2) dopamine receptor ligand 2-[4-... 2 3
D(3) dopamine receptor and D(2) dopamine receptor ligand SureC... 5 4
Dihydrofolate reductase inhibitor AC1LA5HU family 8 4
Dihydrofolate reductase inhibitor AC1L9XPA family 6 5
Bifunctional dihydrofolate reductase-thymidylate synthase and ... 6 13
Cellular tumor antigen p53 and Lysosomal alpha-glucosidase inh... 1 6
Neuropeptide Y receptor type 1 ligand 1-[3-[1-(cyclohexylmethy... 15 9
Neuronal acetylcholine receptor subunit alpha-4 and Neuronal a... 2 0
D(4) dopamine receptor and D(2) dopamine receptor ligand AGN-P... 3 6
Neuropeptide Y receptor type 5 ligand 3-[2-[6-[2-[(2-methylpro... 1 0
cGMP-specific 3',5'-cyclic phosphodiesterase inhibitor SureCN6... 2 4
Cannabinoid receptor 2 and Cannabinoid receptor 1 ligand AGN-P... 2 2
Cathepsin S and Cathepsin K inhibitor AGN-PC-07YOWR family 1 0
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subun... 6 12
Coagulation factor X and Cationic trypsin inhibitor AGN-PC-075... 26 7
Insulin-like growth factor 1 receptor ligand 3qqu family 2 12
Cholecystokinin receptor type A ligand AGN-PC-0A9ULH family 8 8
Melatonin receptor type 1B ligand CHEMBL1802020 family 2 7
Melatonin receptor type 1B and Melatonin receptor type 1A liga... 1 0
Cyclin-dependent kinase 4 and G1/S-specific cyclin-D1 inhibito... 9 10
Insulin receptor and Insulin-like growth factor 1 receptor lig... 17 7
Dual specificity protein kinase TTK inhibitor 6-N-cyclohexyl-2... 3 1
Tyrosine-protein kinase JAK2 inhibitor (2S)-1-[4-[4-[[7-(2-met... 11 27
ALK tyrosine kinase receptor and Nucleophosmin ligand N-[2-met... 8 0
Acyl-CoA desaturase 1 and Acyl-CoA desaturase inhibitor 2-[4-[... 2 6
Corticotropin-releasing factor receptor 1 ligand N-(dicyclopro... 5 1
Protein farnesyltransferase/geranylgeranyltransferase type-1 s... 7 2
Histamine H1 receptor and Histamine H4 receptor ligand 1H-benz... 2 7
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subun... 16 3
cGMP-dependent 3',5'-cyclic phosphodiesterase and cAMP and cAM... 7 4
cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10... 3 2
cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10... 2 0
cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10... 6 0
cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10... 8 1
cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10... 3 1
cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10... 10 4
cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10... 5 0
Tyrosine-protein kinase BTK and Tyrosine-protein kinase Lyn in... 5 7
Tyrosine-protein kinase BTK and Tyrosine-protein kinase Lyn in... 3 0
Receptor tyrosine-protein kinase erbB-2 ligand N-[3-chloro-4-(... 4 3
Cyclin-dependent kinase 1 inhibitor AGN-PC-075VR1 family 1 5
Tyrosine-protein kinase JAK2 and Focal adhesion kinase 1 inhib... 3 1
cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10... 8 2
Glutamate receptor ionotropic, NMDA 1 and Glutamate receptor i... 1 1
Corticotropin-releasing factor receptor 1 and Corticotropin-re... 2 1
Serine/threonine-protein kinase pim-1 and Serine/threonine-pro... 5 8
Hepatocyte growth factor receptor and Cytochrome P450 3A4 liga... 5 2
Interleukin-1 receptor-associated kinase 4 and Interleukin-1 r... 4 0
Insulin-like growth factor 1 receptor ligand 4-(2,3-dihydroind... 1 0
Gamma-aminobutyric acid receptor subunit alpha-1 and Gamma-ami... 4 4
Macrophage colony-stimulating factor 1 receptor and Ephrin typ... 1 0
Vascular endothelial growth factor receptor 2 ligand AGN-PC-00... 8 1
Mitogen-activated protein kinase 14 inhibitor AGN-PC-075YQ1 fa... 4 0
Serine/threonine-protein kinase B-raf and RAF proto-oncogene s... 1 0
Glutamate receptor ionotropic, NMDA 2B and Glutamate receptor ... 4 11
cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10... 3 6
Tyrosine-protein kinase SYK and Tyrosine-protein kinase ITK/TS... 1 0
Aurora kinase A inhibitor AGN-PC-0760BB family 1 1
Histamine H3 receptor and Cytochrome P450 2D6 ligand AGN-PC-07... 1 0
Dual specificity protein kinase TTK inhibitor 6-N-cyclohexyl-2... 12 2
Glycogen synthase kinase-3 beta inhibitor 2-(4-fluorophenyl)-N... 7 3
Bifunctional dihydrofolate reductase-thymidylate synthase and ... 7 16
cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10... 3 0
Lysine--tRNA ligase inhibitor 4-[[[2-(2-piperazin-1-ylpyridin-... 2 1
Somatostatin receptor type 3 and Potassium voltage-gated chann... 3 0
cGMP-dependent 3',5'-cyclic phosphodiesterase and cAMP and cAM... 3 0
cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10... 7 1
Focal adhesion kinase 1 inhibitor AGN-PC-00AVK6 family 1 1
Gamma-aminobutyric acid receptor subunit gamma-2 and Gamma-ami... 25 2
Activated CDC42 kinase 1 inhibitor 5-(2-fluorophenyl)-N-[[(2S)... 5 0
D(4) dopamine receptor and D(2) dopamine receptor ligand AGN-P... 2 2
Vasopressin V1a receptor and Vasopressin V2 receptor ligand 1-... 8 6
Growth hormone secretagogue receptor type 1 ligand SureCN36800... 14 42
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subun... 2 2
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subun... 18 1
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subun... 4 0
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subun... 4 0
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subun... 3 0
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subun... 1 1
ALK tyrosine kinase receptor ligand 4-fluoro-N-[1-[4-(propan-2... 1 0
cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10... 2 0
cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10... 2 1
Angiopoietin-1 receptor and Vascular endothelial growth factor... 4 8
Histamine H4 receptor ligand AGN-PC-00FEQJ family 2 3
Fatty-acid amide hydrolase 1 inhibitor 4-[[3-(4-chlorophenoxy)... 4 2
cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10... 4 1
cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10... 3 2
Tyrosine-protein kinase Lck inhibitor 3-[[2-(benzimidazol-1-yl... 2 0
CGMP-dependent protein kinase inhibitor 1-[2-(4-fluorophenyl)-... 1 4
Corticotropin-releasing factor receptor 1 and Corticotropin-re... 3 14
Transient receptor potential cation channel subfamily V member... 2 4
Gamma-aminobutyric acid receptor subunit gamma-2 and Gamma-ami... 2 2
Vascular endothelial growth factor receptor 2 ligand 2-aminobe... 3 5
Receptor tyrosine-protein kinase erbB-2 ligand SureCN4463897 f... 3 2
Receptor-type tyrosine-protein kinase FLT3 and Vascular endoth... 2 0
Aromatase inhibitor 2-(imidazol-1-ylmethyl)-6-methoxy-1-phenyl... 2 8
Motilin receptor ligand SureCN2012437 family 4 0
Histone-arginine methyltransferase CARM1 inhibitor AGN-PC-00HE... 4 4
cGMP-dependent 3',5'-cyclic phosphodiesterase inhibitor SureCN... 4 0
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subun... 12 2
5-hydroxytryptamine receptor 2C and 5-hydroxytryptamine recept... 2 2
5-hydroxytryptamine receptor 2C and 5-hydroxytryptamine recept... 2 1
Diacylglycerol O-acyltransferase 1 inhibitor 4-[5-[5-(1H-benzi... 7 1
Bifunctional epoxide hydrolase 2 inhibitor 8-(1H-benzimidazole... 1 0
Cannabinoid receptor 1 and Cannabinoid receptor 2 ligand pheny... 1 0
Vascular endothelial growth factor receptor 2 and Angiopoietin... 3 4
Vascular endothelial growth factor receptor 2 and Angiopoietin... 3 3
Angiopoietin-1 receptor and Vascular endothelial growth factor... 2 0
Vascular endothelial growth factor receptor 2 and Angiopoietin... 2 0
Vascular endothelial growth factor receptor 2 and Angiopoietin... 1 0
Histamine H3 receptor and Sodium-dependent serotonin transport... 2 0
Adenosine receptor A2a ligand 8-(3-fluorophenyl)-3-[2-[4-[4-(2... 5 0
Cyclin-dependent kinase 1 inhibitor N-[[5-[(3Z)-3-[4-(methoxym... 3 7
Collagenase 3 inhibitor 1-[6-[4-(1H-benzimidazol-2-yl)phenoxy]... 3 0
Cathepsin K and Cathepsin S inhibitor SureCN4135077 family 2 0
Melanin-concentrating hormone receptor 1 ligand (1S,3S)-3-N-(7... 2 2
Corticotropin-releasing factor receptor 1 and Corticotropin-re... 6 2
C-X-C chemokine receptor type 3 ligand N-[(1R)-1-[1-(4-ethoxyp... 5 9
Tyrosine-protein kinase Lck and Vascular endothelial growth fa... 2 2
Leukotriene A-4 hydrolase inhibitor AGN-PC-00EW8S family 1 2
Epidermal growth factor receptor ligand SureCN2989664 family 5 2
Dihydrofolate reductase inhibitor AC1LAPW3 family 3 0
Gamma-aminobutyric acid receptor subunit pi and GABA theta sub... 2 5
Dihydrofolate reductase inhibitor AGN-PC-001U7R family 3 0
Substance-P receptor ligand N-[(2R)-1-[acetyl-[(2-chlorophenyl... 2 2
Vascular endothelial growth factor receptor 2 and Vascular end... 1 1
Insulin-like growth factor 1 receptor ligand 3-[8-amino-1-(4-e... 9 0
D(3) dopamine receptor and D(2) dopamine receptor ligand SureC... 4 1
Glucagon receptor ligand SureCN2647807 family 3 7
Cyclin-dependent kinase 1 inhibitor AGN-PC-075VQQ family 2 0
Protein farnesyltransferase/geranylgeranyltransferase type-1 s... 3 1
Transient receptor potential cation channel subfamily V member... 18 1
RAF proto-oncogene serine/threonine-protein kinase inhibitor a... 8 6
Vascular endothelial growth factor receptor 2 ligand 2-aminobe... 1 0
Vascular endothelial growth factor receptor 2 ligand 2-aminobe... 2 0
Cyclin-dependent kinase 1 and Receptor tyrosine-protein kinase... 2 3
Histone deacetylase 1 inhibitor (7S)-N-hydroxy-7-[[2-(5-methox... 1 2
Cholecystokinin receptor type A ligand AGN-PC-077L8J family 22 2
Rho-associated protein kinase 2 inhibitor SureCN1519463 family 5 1
Oxytocin receptor and Vasopressin V1b receptor ligand AGN-PC-0... 1 1
Cathepsin S and Cathepsin K inhibitor 2-cyano-pyrropyrimidine,... 4 1
Oxytocin receptor and Vasopressin V1a receptor ligand AGN-PC-0... 4 3
Translocator protein inhibitor AGN-PC-04X3HY family 10 1
RAF proto-oncogene serine/threonine-protein kinase inhibitor a... 5 0
Cholecystokinin receptor type A ligand SureCN3132309 family 11 0
Cholecystokinin receptor type A ligand AGN-PC-077KXF family 2 0
Metabotropic glutamate receptor 2 ligand 2-[[(1R,5S)-6-[(2,5-d... 2 3
Tyrosine-protein kinase SYK and Tyrosine-protein kinase ZAP-70... 3 8
Nociceptin receptor and Delta-type opioid receptor ligand 2-[3... 2 1
Cathepsin S and Cathepsin K inhibitor AGN-PC-078ZDC family 4 2
Adenosine receptor A2a and Adenosine receptor A1 ligand SureCN... 3 5
Platelet-derived growth factor receptor beta and Fibroblast gr... 2 1
cGMP-specific 3',5'-cyclic phosphodiesterase inhibitor AGN-PC-... 3 1
Epidermal growth factor receptor ligand Pyrido[3,4-d]pyrimidin... 3 1
Acyl-CoA desaturase 1 inhibitor AGN-PC-077KJ2 family 1 0
Oxytocin receptor ligand AGN-PC-07C71T family 3 2
cGMP-specific 3',5'-cyclic phosphodiesterase inhibitor AGN-PC-... 7 6
cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10... 2 0
LIM domain kinase 2 and LIM domain kinase 1 inhibitor SureCN36... 1 1
TGF-beta receptor type-1 ligand SureCN373216 family 3 14
Acyl-CoA desaturase 1 and Acyl-CoA desaturase inhibitor AGN-PC... 2 0
Acyl-CoA desaturase 1 inhibitor Pyridazine, 3-[4-(2-ethylpheno... 4 2
Oxysterols receptor LXR-alpha and Oxysterols receptor LXR-beta... 7 4
D(3) dopamine receptor and D(2) dopamine receptor ligand SureC... 1 0
Corticotropin-releasing factor receptor 1 ligand AGN-PC-07ZH03... 1 0
Potassium-transporting ATPase alpha chain 1 and Potassium-tran... 2 11
Potassium voltage-gated channel subfamily H member 2 and Melan... 2 1
Lysosomal Pro-X carboxypeptidase inhibitor 4-[6-[(2S)-2-(5,6-d... 2 2
Sodium channel protein type 5 subunit alpha and Sodium channel... 15 8
Sphingosine 1-phosphate receptor 1 ligand (2S)-2-[[2-(1H-imida... 4 7
Metabotropic glutamate receptor 5 ligand AGN-PC-0760YR family 1 0
Mitogen-activated protein kinase 10 inhibitor cyclopropyl-[(3R... 1 0
Metabotropic glutamate receptor 5 ligand 2-[4-(4-fluoro-3-meth... 1 0
Serine/threonine-protein kinase PLK1 inhibitor SureCN3992071 f... 1 0
Glucokinase inhibitor SureCN1657199 family 10 6


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00169099 CHEMBL1916137 Bioactive 6-fluoro-3,4-dimethyl-1-(3-methylpyridin-4-yl)-8-(2,2,2-trifluoroethoxy)imidazo[1,5-a]quinoxaline
CFAMM00169216 CHEMBL1289503 Bioactive 3-pyridin-2-yl-8-[6-(trifluoromethoxy)-1H-benzimidazol-2-yl]-1-oxa-3-azaspiro[4.5]decan-2-one
CFAMM00169257 CHEMBL243911 Bioactive benzimidazole-urea, 33
CFAMM00169115 CHEMBL397497 Bioactive AGN-PC-01LUUE
CFAMM00169211 CHEMBL231370 Bioactive 2-aminobenzimidazole, 12
CFAMM00169134 DNCL002421 Clinical Trial Drug RAF265

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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