CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

Family Name Multiple kinase Inhibitor MGCD265 Family
No. of Seeds 19 No. of Other Members 71
Family Centroid CFAMM00169612 Functional Category Clinical Trial Drug
Superfamily Multiple kinase and Aurora kinase A Binder Superfamily
Class Class 985

Cousin Family NamesSeedsMembers
Transient receptor potential cation channel subfamily V member... 42 32
Serine/threonine-protein kinase PLK1 Inhibitor GSK461364 Family 40 84
Mast/stem cell growth factor receptor Kit and Vascular endothe... 1 4
Hepatocyte growth factor receptor and Receptor-type tyrosine-p... 12 26
Adenosine receptor A2a and Adenosine receptor A1 ligand 2-(3-c... 3 3
E-selectin and Intercellular adhesion molecule 1 inhibitor 4-(... 2 0
Hepatocyte growth factor receptor ligand AGN-PC-077PZW family 1 0
Vascular endothelial growth factor receptor 2 and Hepatocyte g... 2 2
Serine/threonine-protein kinase PLK1 inhibitor SureCN2523858 f... 4 2
Vascular endothelial growth factor receptor 2 and Hepatocyte g... 1 4
Hepatocyte growth factor receptor and Macrophage-stimulating p... 4 0


External ID

Functional Category

Molecule Name

CFAMM00169574 CHEMBL517469 Bioactive AGN-PC-00RYYZ
CFAMM00169554 CHEMBL567475 Bioactive AGN-PC-07CRPP
CFAMM00169581 CHEMBL465131 Bioactive AGN-PC-00S0IH
CFAMM00169587 CHEMBL565807 Bioactive AGN-PC-00S0II
CFAMM00169613 CHEMBL584701 Bioactive AGN-PC-00RZZK
CFAMM00169593 CHEMBL449757 Bioactive AGN-PC-078XEQ
CFAMM00169566 CHEMBL254964 Bioactive AGN-PC-00DTLN
CFAMM00169580 CHEMBL465130 Bioactive AGN-PC-078XRY
CFAMM00169545 CHEMBL565990 Bioactive AGN-PC-07CRR2
CFAMM00169571 CHEMBL258240 Bioactive AGN-PC-00ENFY
CFAMM00169585 CHEMBL566844 Bioactive SureCN307785
CFAMM00169550 CHEMBL565782 Bioactive AGN-PC-00RZCR
CFAMM00169537 CHEMBL565603 Bioactive AGN-PC-07CRQM
CFAMM00169543 CHEMBL576504 Bioactive AGN-PC-07CRR3
CFAMM00169589 CHEMBL602703 Bioactive SureCN308057
CFAMM00169542 CHEMBL585205 Bioactive AGN-PC-00RZGX
CFAMM00169615 CHEMBL464211 Bioactive AGN-PC-00RYYY
CFAMM00169568 CHEMBL462232 Bioactive SureCN896306
CFAMM00169612 DNCL002525 Clinical Trial Drug MGCD265

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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