CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

Family Name Nuclear factor NF-kappa-B p100 subunit Inhibitor GMX1777 Family
No. of Seeds 3 No. of Other Members 7
Family Centroid CFAMM00132904 Functional Category Clinical Trial Drug
Superfamily Nuclear factor NF-kappa-B p100 subunit Inhibitor GMX1777 Superfamily
Class Class 873

Cousin Family NamesSeedsMembers
Amyloid beta A4 protein Inhibitor Florbetapir F-18 Family 8 265
Serine/threonine-protein kinase Chk1 and Serine/threonine-prot... 23 121
AP26113 family 16 90
Vascular endothelial growth factor receptor 2 ligand 1-[4-[6-a... 11 13
Receptor tyrosine-protein kinase erbB-2 ligand N-[3-chloro-4-(... 4 3
Receptor tyrosine-protein kinase erbB-2 ligand 2-[2-[4-[3-chlo... 4 5
Wee1-like protein kinase and ALK tyrosine kinase receptor liga... 1 9


External ID

Functional Category

Molecule Name

CFAMM00132895 CHEMBL17289 Bioactive 2-[6-(4-chlorophenoxy)hexyl]-1-cyano-3-pyridin-4-ylguanidine
CFAMM00132900 CHEMBL474802 Bioactive 2-[6-(4-chlorophenoxy)hexyl]-1-ethynyl-3-pyridin-4-ylguanidine
CFAMM00132904 DCL000120 Clinical Trial Drug GMX1777

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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