CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFCD757
Family Name Pixantrone family
No. of Seeds 2 No. of Other Members 3
Family Centroid CFAMM00171008 Functional Category Clinical Trial Drug
Superfamily Pixantrone Superfamily
Class Class 1284

Cousin Family NamesSeedsMembers
Cytochrome P450 11B1, mitochondrial Inhibitor Metyrapone Family 9 243
DNA topoisomerase 2-beta Inhibitor Rosoxacin Family 1 5
Neuromedin-K receptor Ligand SB222200 Family 17 235
Glutamate receptor AMPA subtype Ligand CX-516 Family 9 24
D(3) dopamine receptor Ligand SB-277011 Family 13 178
C-C chemokine receptor type 3 Ligand YM-344031 Family 19 106
Cannabinoid receptor 2 Ligand JWH-167 Family 25 168
Cytochrome P450 11B1, mitochondrial and Aromatase Inhibitor 5-... 3 5
Histone deacetylase 1 and Histone deacetylase 2 Inhibitor N-(4... 4 21
Cannabinoid receptor 2 Ligand JWH-204 Family 6 10
Cannabinoid receptor 2 Ligand JWH-249 Family 7 13
Inosine-5'-monophosphate dehydrogenase 2 Inhibitor 1-methyl-1h... 24 50
Transient receptor potential cation channel subfamily V member... 6 23
Cannabinoid receptor 1 and Cannabinoid receptor 2 Ligand JWH-3... 37 1
Cannabinoid receptor 1 and Cannabinoid receptor 2 Ligand JWH-2... 8 1
Bifunctional epoxide hydrolase 2 Inhibitor N-(3,3-diphenyl-pro... 6 14
Telomerase reverse transcriptase Inhibitor 2,3-dimethylnaphtho... 1 0
Mitogen-activated protein kinase 14 Inhibitor N-(4-fluorobenzy... 19 32
Glutamate receptor 1 Ligand Piriqualone Family 8 67
Vasopressin V2 receptor Ligand YM-35278 Family 33 38
Acetylcholinesterase and Cholinesterase Inhibitor 7-oxo-7h-dib... 2 3
Metabotropic glutamate receptor 1 ligand GTPL6334 family 6 4
5-hydroxytryptamine receptor 1A and D(2) dopamine receptor lig... 18 3
Renin inhibitor [2-[(3-fluoro-2-methylphenyl)methyl]-6-methyl-... 2 1
Metabotropic glutamate receptor 1 ligand AGN-PC-07CPMZ family 1 0
Amine oxidase [flavin-containing] A inhibitor CHEMBL1917530 fa... 1 0
Methionine aminopeptidase 1 inhibitor ethyl 4-[4-(2-pyridin-2-... 2 3
Metabotropic glutamate receptor 5 ligand 3-methyl-1-[2-[3-(tri... 3 1
DNA topoisomerase 4 subunit A inhibitor SureCN2388284 family 2 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00171008 DNCL002697 Clinical Trial Drug Pixantrone
CFAMM00171005 DNC010240 Investigative Drug NSC-745887

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

27291 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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