CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFCD78
Family Name Glycine receptor subunit beta Ligand Gw 468816 Family
No. of Seeds 4 No. of Other Members 67
Family Centroid CFAMM00133096 Functional Category Clinical Trial Drug
Superfamily Glycine receptor subunit beta Ligand Gw 468816 Superfamily
Class Class 702

Cousin Family NamesSeedsMembers
Angiotensin-converting enzyme Inhibitor Benazepril Family 7 123
Integrin beta-1 Inhibitor R411 Family 33 44
Potassium voltage-gated channel subfamily KQT member 1 Ligand ... 19 186
Cholecystokinin receptor type A Ligand VL-1499 Family 12 133
Delta-type opioid receptor and Mu-type opioid receptor Ligand ... 14 110
Phospholipase D1 Inhibitor Halopemide Family 17 111
D(2) dopamine receptor Ligand PD-168077 Family 6 5
Melanocortin receptor 4 and Melanocortin receptor 5 ligand N-[... 16 117
Coagulation factor X inhibitor 3-amino-4-chloro-N-[(1R)-2-[4-(... 1 1
Integrin beta-1 and Integrin alpha-4 inhibitor (E)-3-[4-[(2,6-... 3 1
Integrin beta-1 and Integrin alpha-4 inhibitor (2S)-3-[4-[(2,6... 7 3
D(3) dopamine receptor and D(2) dopamine receptor ligand N-[(E... 24 11
Integrin beta-1 and Integrin alpha-4 inhibitor SureCN6823871 f... 9 0
Cholecystokinin receptor type A and Gastrin/cholecystokinin ty... 3 5
Melanocortin receptor 4 ligand N-[(2R)-3-(4-chlorophenyl)-1-[4... 11 9
Substance-P receptor and Substance-K receptor ligand AGN-PC-07... 5 2
Melanocortin receptor 4 and Cytochrome P450 3A4 ligand 2-amino... 52 12
Integrin beta-1 and Integrin alpha-4 inhibitor (2S)-2-[[1-[2-(... 12 2
C-C chemokine receptor type 1 ligand 3-[2-(carbamoylamino)phen... 2 1
fMet-Leu-Phe receptor ligand (2S)-2-[[(2S)-2-[[(2S)-2-[(4-chlo... 1 0
Integrin beta-1 and Integrin alpha-4 inhibitor (2S)-2-[(4-brom... 2 0
Integrin beta-3 and Integrin alpha-V inhibitor 3-[[[3-(diamino... 5 4
Glucagon receptor and Adenylate cyclase type 1 ligand AGN-PC-0... 1 0
E3 ubiquitin-protein ligase Mdm2 inhibitor methyl 2-(4-chlorop... 2 8
Glutamate receptor ionotropic, NMDA 1 and Glutamate receptor i... 1 4
Glutamate receptor ionotropic, NMDA 1 ligand (2R,4S)-5,7-dichl... 1 0
Cholecystokinin receptor type A and Gastrin/cholecystokinin ty... 1 0
Glutamate receptor ionotropic, NMDA 1 ligand SureCN9463331 family 1 1
E3 ubiquitin-protein ligase Mdm2 inhibitor SureCN5171589 family 10 0
4-oxo-2-[(2-oxo1H-quinoline-4-carbonyl)amino]butanoic NP (s)-m... 1 3


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00133133 CHEMBL294384 Bioactive (2R,4S)-7-chloro-5-iodo-4-[(2-phenylacetyl)amino]-1,2,3,4-tetrahydroquinoline-2-carboxylic acid
CFAMM00133081 CHEMBL62148 Bioactive (2R,4S)-7-chloro-5-iodo-4-(phenylcarbamoylamino)-1,2,3,4-tetrahydroquinoline-2-carboxylic acid
CFAMM00133096 DCL000126 Clinical Trial Drug GW 468816
CFAMM00133097 DNC001200 Investigative Drug Rebamipide

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

21760 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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