CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFCD8
Family Name RAC-gamma serine/threonine-protein kinase and Ribosomal protein S6 kinase beta-1 Inhibitor XL418 Family
No. of Seeds 3 No. of Other Members 5
Family Centroid CFAMM00126942 Functional Category Clinical Trial Drug
Superfamily RAC-gamma serine/threonine-protein kinase and Ribosomal protein S6 kinase beta-1 Inhibitor XL418 Superfamily
Class Class 819

Cousin Family NamesSeedsMembers
Aurora kinase B and Tyrosine-protein kinase Lck Inhibitor CGP-... 2 29
Aurora kinase A and Aurora kinase B inhibitor 3uol family 6 5
Prelamin-A/C inhibitor CHEMBL1472945 family 1 32
Adenosine receptor A3 and Adenosine receptor A1 ligand CHEMBL1... 7 4
Serine/threonine-protein kinase pim-2 and Serine/threonine-pro... 9 2
Ribosomal protein S6 kinase beta-1 and RAC-alpha serine/threon... 2 1
Casein kinase II subunit alpha inhibitor 2pvj family 3 1
Activated CDC42 kinase 1 inhibitor AGN-PC-078WDN family 7 2


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00126945 CHEMBL2012702 Bioactive N-[3-[4-(3-bromo-2H-pyrazolo[3,4-d]pyrimidin-4-yl)piperazin-1-yl]-5-chloro-2-methylphenyl]-N',N'-dimethylethane-1,2-diamine
CFAMM00126943 CHEMBL2016771 Bioactive 3-[4-(3-bromo-2H-pyrazolo[3,4-d]pyrimidin-4-yl)piperazin-1-yl]-5-chloro-2-methyl-N-(2-pyrrolidin-1-ylethyl)aniline
CFAMM00126942 DCL000009 Clinical Trial Drug XL418

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

21767 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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