CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFCD814
Family Name Pitolisant family
No. of Seeds 4 No. of Other Members 24
Family Centroid CFAMM00172109 Functional Category Clinical Trial Drug
Superfamily Pitolisant Superfamily
Class Class 1323

Cousin Family NamesSeedsMembers
Sodium-dependent dopamine transporter inhibitor substituted ph... 22 416
Histamine H1 receptor Ligand Clemastine Family 5 76
Histamine H1 receptor ligand piperazine derivative Cyclizine F... 16 140
Histamine H1 receptor Ligand Diphenhydramine Family 5 75
Alpha-1B adrenergic receptor ligand Morpholine derivative Phen... 4 152
Muscarinic acetylcholine receptor M1 Ligand Trihexyphenidyl Fa... 14 199
Histamine H1 receptor ligand diphenylpiperidine analog Dipheny... 13 224
Muscarinic acetylcholine receptor M3 Ligand Diphemanil Methyls... 22 45
Nicotinic acetylcholine receptor Ligand Benztropine Mesylate F... 10 20
Delta-type opioid receptor and Kappa-type opioid receptor Liga... 7 19
Potassium voltage-gated channel subfamily H member 2 Ligand [1... 2 23
Glutamate receptor ionotropic, NMDA 2B and Glutamate receptor ... 9 7
Sodium-dependent dopamine transporter Inhibitor (+/-)-threo-ri... 5 12
Transporter and Sodium-dependent dopamine transporter inhibito... 3 42
Histamine H3 receptor ligand 1-[[4-[4-[(1R)-4-methoxy-1-[(2S)-... 2 0
Vesicular acetylcholine transporter inhibitor 2-Naphthalenol, ... 3 2
Sodium-dependent dopamine transporter inhibitor ethyl (3S,4S)-... 6 11
Sodium-dependent dopamine transporter inhibitor (1R)-1-[(3S,4S... 1 1
Sigma non-opioid intracellular receptor 1 and 5-hydroxytryptam... 1 1
Sigma non-opioid intracellular receptor 1 and 5-hydroxytryptam... 3 12
Sigma non-opioid intracellular receptor 1 and 5-hydroxytryptam... 3 0
Vesicular acetylcholine transporter inhibitor (1R,2R)-2-spiro[... 3 2
Sodium-dependent dopamine transporter and Sodium-dependent ser... 3 3
Transporter and Sodium-dependent dopamine transporter inhibito... 2 1
Sodium-dependent dopamine transporter and Transporter inhibito... 1 1
Cathepsin K and Cathepsin L1 inhibitor 3-(phenylmethoxymethyl)... 1 0
Mu-type opioid receptor ligand CHEMBL2373396 family 2 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00172109 DNCL003130 Clinical Trial Drug Pitolisant
CFAMM00172130 DNC009608 Investigative Drug 4-Butyl-1-[3-(phenylpropoxy)propyl]piperidine
CFAMM00172126 DNC009607 Investigative Drug 4-Propyl-1-[3-(phenylpropoxy)propyl]piperidine
CFAMM00172111 DNC009610 Investigative Drug 1-(3-(3-phenylpropoxy)propyl)piperidine

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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