CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFCD826
Family Name C-Jun N-terminal kinase Inhibitor CC-930 Family
No. of Seeds 2 No. of Other Members 9
Family Centroid CFAMM00172581 Functional Category Clinical Trial Drug
Superfamily C-Jun N-terminal kinase Inhibitor CC-930 Superfamily
Class Class 1333

Cousin Family NamesSeedsMembers
Toll-like receptor 7 Ligand Imiquimod Family 3 237
Histamine H1 receptor Ligand Mizolastine Family 14 603
Metabotropic glutamate receptor 5 Ligand ADX-48621 Family 15 444
C-X-C chemokine receptor type 4 Ligand AMD-070 Family 12 800
Cyclin-dependent kinase 2 Inhibitor Seliciclib Family 29 292
Fibroblast growth factor receptor 2 and Fibroblast growth fact... 11 86
Adenosine receptor A3 Ligand CF101 Family 24 560
Adenosine receptor A2a Ligand MRE-0094 Family 10 108
5-hydroxytryptamine receptor 1A and D(2) dopamine receptor Lig... 14 234
Adenosine receptor A1 Ligand SLV320 Family 6 79
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subun... 35 270
TOK-001 family 2 7
GDC-0349 family 44 77
Glucan synthesis regulatory protein Inhibitor Pyridobenzimidaz... 2 12
Prostaglandin G/H synthase 2 Inhibitor RWJ-67657 Family 3 33
Equilibrative nucleoside/nucleobase transporter Inhibitor Nitr... 23 98
Amine oxidase [flavin-containing] A and Amine oxidase [flavin-... 2 7
Adenosine receptor A1 and Adenosine receptor A2a Ligand N6-met... 7 72
Epidermal growth factor receptor Ligand PD-158780 Family 98 89
Methionine aminopeptidase 2 Inhibitor 2-(pyridin-2-yl)-1h-benz... 6 19
Metabotropic glutamate receptor 5 Ligand 3-(4-pyridin-2-yl-imi... 6 5
Adenosine receptor A1 Ligand Phenyl-(9-phenyl-9h-purin-6-yl)-a... 7 12
Adenosine receptor A1 and Adenosine receptor A2a Ligand GW-328... 26 94
RAC-gamma serine/threonine-protein kinase and Rho-associated p... 16 46
Adenosine receptor A3 and Dual specificity mitogen-activated p... 5 27
Adenosine receptor A1 and Adenosine receptor A2a Ligand N6-met... 21 57
Adenosine receptor A1 and Adenosine receptor A2a Ligand 2-[(4-... 15 9
Adenosine receptor A1 and Adenosine receptor A2a Ligand 2-(3''... 12 5
Adenosine receptor A1 and Adenosine receptor A2a Ligand 2-(3''... 2 2
Adenosine receptor A2a and Adenosine receptor A3 Ligand 2-(3''... 8 10
Proto-oncogene tyrosine-protein kinase Src Inhibitor BMS-27970... 41 59
RAF proto-oncogene serine/threonine-protein kinase Inhibitor L... 219 124
Potassium voltage-gated channel subfamily H member 2 Ligand AZ... 21 42
Inositol 1,4,5-trisphosphate receptor type 3 Ligand 5'-deoxy-5... 11 8
Adenosine kinase inhibitor GP683 family 12 7
Mitogen-activated protein kinase 8 and Mitogen-activated prote... 2 5
cGMP-specific 3',5'-cyclic phosphodiesterase inhibitor AGN-PC-... 34 11
cGMP-specific 3',5'-cyclic phosphodiesterase inhibitor SureCN5... 6 24
5-hydroxytryptamine receptor 3A and 5-hydroxytryptamine recept... 7 4
S-methyl-5'-thioadenosine phosphorylase inhibitor SureCN997478... 8 0
Sorbitol dehydrogenase inhibitor SureCN6335187 family 2 6
Adenosine kinase inhibitor N-cyclopropyl-2-[[1-[(2R,3R,4S,5R)-... 4 1
Mitogen-activated protein kinase 14 inhibitor AGN-PC-03XQYG fa... 7 1
Insulin-like growth factor 1 receptor ligand AGN-PC-09QIDN family 1 3
Adenosine deaminase inhibitor AGN-PC-00FYYU family 4 5
Dual specificity protein kinase TTK inhibitor 4-[[2-(2-methyl-... 1 0
Aurora kinase A and Cyclin-dependent kinase 4 inhibitor 7-cycl... 1 0
Tyrosine-protein kinase JAK1 and Non-receptor tyrosine-protein... 7 0
CGMP-dependent protein kinase inhibitor SureCN14561191 family 4 0
Motilin receptor ligand SureCN2004322 family 2 1
Tyrosine-protein kinase JAK1 and Tyrosine-protein kinase JAK2 ... 16 0
Mitogen-activated protein kinase 8 and Mitogen-activated prote... 2 1
Adenosine receptor A1 ligand 2-[4-[[2-[4-[[9-[(3R,4S,5R)-3,4-d... 14 0
Serine/threonine-protein kinase mTOR inhibitor 1-ethyl-3-[4-[6... 4 1
Tyrosine-protein kinase ITK/TSK and Aurora kinase B inhibitor ... 1 1
Nociceptin receptor and Potassium voltage-gated channel subfam... 5 2
Adenosylhomocysteinase inhibitor Carbocyclic 3-deazaadenosine ... 1 0
G2/mitotic-specific cyclin-B2 and Cyclin-dependent kinase 1 in... 2 1
C-C chemokine receptor type 3 and Cytochrome P450 2D6 ligand 1... 1 0
Metabotropic glutamate receptor 1 ligand AGN-PC-00FV3S family 2 0
Cyclin-dependent kinase 2 inhibitor SureCN3549598 family 3 1
Ribosomal protein S6 kinase beta-1 and Aurora kinase B inhibit... 1 5
5-hydroxytryptamine receptor 3A ligand AGN-PC-077D8K family 3 1
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subun... 1 0
Cyclin-A2 and Cyclin-dependent kinase 2 inhibitor (2S)-2-[[9-p... 4 5


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00172581 DNCL003418 Clinical Trial Drug CC-930

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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