CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFCD839
Family Name Ceramide glucosyltransferase Inhibitor Eliglustat Tartrate Family
No. of Seeds 3 No. of Other Members 2
Family Centroid CFAMM00173035 Functional Category Clinical Trial Drug
Superfamily Neurotensin receptor type 1 and Ceramide glucosyltransferase Binder Superfamily
Class Class 858

Cousin Family NamesSeedsMembers
Beta adrenergic receptor Ligand Dipivefrin Family 3 55
Renin Inhibitor Aliskiren Family 28 107
Plasmepsin-1 and Plasmepsin-2 Inhibitor PS-777621 Family 11 13
72 kDa type IV collagenase and Matrix metalloproteinase-9 Inhi... 9 12
Tubulin beta chain Inhibitor 6-ile-ustiloxin Family 4 3
Glycine receptor subunit beta Ligand ORG-25543 Family 10 153
Calpain-2 catalytic subunit and Calpain-1 catalytic subunit in... 5 2
Renin inhibitor N-[(2S,4S,5S,7S)-7-[2-(1-acetylpiperidin-4-yl)... 2 1
Transient receptor potential cation channel subfamily V member... 3 18
Prothrombin inhibitor (2S)-N-[(4-aminocyclohexyl)methyl]-1-[2-... 1 0
Renin inhibitor (2S,4S,5S,7S)-5-amino-4-hydroxy-7-[[4-methoxy-... 2 0
Renin inhibitor N-[(2S,3S,5R)-2-amino-6-(butylamino)-3-hydroxy... 5 1


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00173037 CHEMBL1911678 Bioactive N-[(1R,2S)-1-(2,3-dihydro-1,4-benzodioxin-6-yl)-1-hydroxy-3-pyrrolidin-1-ylpropan-2-yl]nonanamide
CFAMM00173036 CHEMBL1911679 Bioactive N-[(1R,2S)-1-(2,3-dihydro-1,4-benzodioxin-6-yl)-1-hydroxy-3-pyrrolidin-1-ylpropan-2-yl]octanamide
CFAMM00173035 DNCL003543 Clinical Trial Drug Eliglustat tartrate

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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