CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFCD840
Family Name Toll-like receptor 7 Ligand GS-9620 Family
No. of Seeds 2 No. of Other Members 4
Family Centroid CFAMM00173046 Functional Category Clinical Trial Drug
Superfamily Translocator protein and Toll-like receptor 7 Binder Superfamily
Class Class 1027

Cousin Family NamesSeedsMembers
Cyclin-dependent kinase 2 Inhibitor Seliciclib Family 29 292
Cyclin-dependent kinase 4 Inhibitor PD-332991 Family 13 155
Dipeptidyl peptidase 4 Inhibitor Linagliptin Family 10 81
cAMP-specific 3',5'-cyclic phosphodiesterase 4D Inhibitor Arof... 3 196
Translocator protein Inhibitor Emapunil Family 7 89
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subun... 35 270
Dipeptidyl peptidase 4 Inhibitor SSR-162369 Family 8 27
GP-531 family 1 33
Serine/threonine-protein kinase mTOR Inhibitor AZD2014 Family 2 41
GDC-0349 family 44 77
Adenosine receptor A1 and Adenosine receptor A2a Ligand 8-phen... 12 213
Adenosine receptor A1 and Adenosine receptor A2b Ligand PSB-11... 34 26
Herpes simplex virus type 1 thymidine kinase Inhibitor 9-(4-hy... 2 13
Serine/threonine-protein kinase B-raf Inhibitor 2-(benzylamino... 7 117
Adenosine receptor A3 Ligand 1-benzyl-1h-1,3,4b,9-tetraaza-flu... 19 165
D(2) dopamine receptor and D(3) dopamine receptor Ligand A-706... 4 20
Adenosine receptor A1 and Adenosine receptor A2a Ligand N-(2,6... 22 18
Adenosine receptor A2a Ligand (e,e)-8-(4-phenylbutadien-1-yl)c... 11 43
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subun... 24 79
cGMP-specific 3',5'-cyclic phosphodiesterase Inhibitor SCH-577... 9 29
Serine/threonine-protein kinase mTOR and Phosphatidylinositol ... 25 4
Serine/threonine-protein kinase mTOR and Phosphatidylinositol ... 10 3
Serine/threonine-protein kinase mTOR and Phosphatidylinositol ... 7 0
Serine/threonine-protein kinase mTOR and Phosphatidylinositol ... 13 10
Adenosine receptor A2a and Adenosine receptor A1 ligand SureCN... 2 1
Dipeptidyl peptidase 4 inhibitor Xanthine Analogue 4 family 1 4
Dipeptidyl peptidase 4 inhibitor AGN-PC-046QKE family 3 5
Cathepsin K and Potassium voltage-gated channel subfamily H me... 5 1
Vascular endothelial growth factor receptor 2 ligand AC1LLCDM ... 1 2
Prelamin-A/C inhibitor CHEMBL1503535 family 1 0
Cellular tumor antigen p53 and Thyrotropin receptor ligand CHE... 1 5
C-C chemokine receptor type 5 and Potassium voltage-gated chan... 21 32
Toll-like receptor 7 ligand 6-amino-2-(butylamino)-9-[[4-(dime... 5 4
Corticotropin-releasing factor receptor 1 ligand 7-[bis(2-meth... 3 0
Serine/threonine-protein kinase mTOR inhibitor SureCN2707225 f... 29 4
Serine/threonine-protein kinase mTOR inhibitor AGN-PC-088SNX f... 1 0
Neuronal acetylcholine receptor subunit alpha-4 and Neuronal a... 5 4
Translocator protein inhibitor N-butan-2-yl-4-(2-chlorophenyl)... 14 12
Serine/threonine-protein kinase mTOR and Phosphatidylinositol ... 10 3
Adenosine receptor A3 ligand 3-(cyclopropylmethyl)-8-methoxy-1... 1 0
G-protein coupled bile acid receptor 1 ligand 2-(ethylamino)-6... 5 4
Serine/threonine-protein kinase mTOR inhibitor 1-ethyl-3-[4-[6... 4 1
Prothrombin inhibitor 2-[4-methyl-5-[[[2-[6-methyl-2-oxo-3-(2-... 1 0
Receptor-type tyrosine-protein kinase FLT3 ligand 4-[6-amino-5... 1 1
Serine/threonine-protein kinase mTOR and Phosphatidylinositol ... 26 0
Serine/threonine-protein kinase mTOR and Phosphatidylinositol ... 2 0
Toll-like receptor 7 ligand SureCN2060223 family 5 2


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00173043 CHEMBL484765 Bioactive AGN-PC-00IL0Z
CFAMM00173046 DNCL003552 Clinical Trial Drug GS-9620

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

46009 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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