CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFCD87
Family Name Kinesin-like protein KIF11 Inhibitor Ispinesib Family
No. of Seeds 4 No. of Other Members 37
Family Centroid CFAMM00133435 Functional Category Clinical Trial Drug
Superfamily Kinesin-like protein KIF11 Inhibitor Ispinesib Superfamily
Class Class 882

Cousin Family NamesSeedsMembers
Extracellular calcium-sensing receptor Ligand 3-phenethyl-2-ph... 3 137
Poly [ADP-ribose] polymerase 1 Inhibitor 5-chloro-2-methyl-3h-... 1 1
Voltage-dependent T-type calcium channel subunit alpha-1I Liga... 7 35
D(3) dopamine receptor and D(2) dopamine receptor ligand N-[(E... 24 11
Ghrelin/growth hormone secretagogue receptor ligand AGN-PC-00A... 7 27
Histone deacetylase 6 and Histone deacetylase 8 inhibitor (E)-... 2 8
Poly [ADP-ribose] polymerase 1 inhibitor 8-chloro-2-[(3S)-3-(4... 2 8
Coagulation factor X inhibitor N-(4-chlorophenyl)-2-[[4-(2-oxo... 2 0
Inositol monophosphatase 1 and Retinal dehydrogenase 1 inhibit... 1 2
5-hydroxytryptamine receptor 1A and 5-hydroxytryptamine recept... 2 2
Acetylcholinesterase and Cholinesterase inhibitor N-[4-[(E)-(6... 1 1
Carbonic anhydrase 9 and Carbonic anhydrase 12 inhibitor 4-oxo... 3 1
Delta-type opioid receptor ligand SureCN7549631 family 6 3
Glutamate receptor 1 and Glutamate receptor 2 ligand SureCN621... 1 3
Prostaglandin E synthase inhibitor 2-chloro-N-[3-[[4-(3-chloro... 5 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00133464 CHEMBL2347651 Bioactive Ispinesib mesylate
CFAMM00133452 DCL000224 Clinical Trial Drug SB-743921
CFAMM00133435 DCL000139 Clinical Trial Drug Ispinesib
CFAMM00133458 DNC007593 Investigative Drug SB-731489

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

21767 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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