CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFCD91
Family Name Squalene synthase Inhibitor Lapaquistat Acetate Family
No. of Seeds 27 No. of Other Members 38
Family Centroid CFAMM00133581 Functional Category Clinical Trial Drug
Superfamily Squalene synthase Inhibitor Lapaquistat Acetate Superfamily
Class Class 886

Cousin Family NamesSeedsMembers
Squalene synthase inhibitor AGN-PC-09M2X2 family 12 22
Squalene synthase inhibitor (3S)-1-[4-[2,4-dichloro-N-(2,2-dim... 1 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00133620 CHEMBL1685014 Bioactive AGN-PC-09QKEG
CFAMM00133587 CHEMBL1685025 Bioactive AGN-PC-09M2ZT
CFAMM00133600 CHEMBL1819477 Bioactive ethyl 1-[4-[4-chloro-N-(2,2-dimethylpropyl)-2-[(S)-hydroxy-(2-methoxyphenyl)methyl]-6-methoxyanilino]-4-oxobutanoyl]piperidine-4-carboxylate
CFAMM00133613 CHEMBL1819580 Bioactive (3S)-1-[4-[4-chloro-2-(2,2-dimethylpropoxy)-N-(2,2-dimethylpropyl)-6-[(S)-hydroxy-(2-methoxyphenyl)methyl]anilino]-4-oxobutanoyl]piperidine-3-carboxylic acid
CFAMM00133580 CHEMBL1685029 Bioactive AGN-PC-09QM3O
CFAMM00133593 CHEMBL1685008 Bioactive AGN-PC-09QLAN
CFAMM00133606 CHEMBL1819571 Bioactive ethyl 1-[4-[4-chloro-N-(2,2-dimethylpropyl)-2-ethoxy-6-[(S)-hydroxy-(2-methoxyphenyl)methyl]anilino]-4-oxobutanoyl]piperidine-4-carboxylate
CFAMM00133633 CHEMBL1819567 Bioactive (3S)-1-[4-[4-chloro-N-(2,2-dimethylpropyl)-2-[(S)-hydroxy-(2-methoxyphenyl)methyl]-6-methoxyanilino]-4-oxobutanoyl]piperidine-3-carboxylic acid
CFAMM00133579 CHEMBL1685028 Bioactive AGN-PC-09QIXT
CFAMM00133605 CHEMBL1819577 Bioactive (3S)-1-[4-[4-chloro-N-(2,2-dimethylpropyl)-2-[(S)-hydroxy-(2-methoxyphenyl)methyl]-6-propan-2-yloxyanilino]-4-oxobutanoyl]piperidine-3-carboxylic acid
CFAMM00133598 CHEMBL1684996 Bioactive AGN-PC-09M2ZU
CFAMM00133638 CHEMBL1819561 Bioactive ethyl (3S)-1-[4-[4-chloro-N-(2,2-dimethylpropyl)-2-[(S)-hydroxy-(2-methoxyphenyl)methyl]-6-methoxyanilino]-4-oxobutanoyl]piperidine-3-carboxylate
CFAMM00133591 CHEMBL1685005 Bioactive AGN-PC-09QMX9
CFAMM00133604 CHEMBL1819574 Bioactive (3S)-1-[4-[4-chloro-N-(2,2-dimethylpropyl)-2-ethoxy-6-[(S)-hydroxy-(2-methoxyphenyl)methyl]anilino]-4-oxobutanoyl]piperidine-3-carboxylic acid
CFAMM00133631 CHEMBL1819569 Bioactive (3R)-1-[4-[4-chloro-N-(2,2-dimethylpropyl)-2-[(S)-hydroxy-(2-methoxyphenyl)methyl]-6-methoxyanilino]-4-oxobutanoyl]piperidine-3-carboxylic acid
CFAMM00133623 CHEMBL1685018 Bioactive AGN-PC-09QIOG
CFAMM00133590 CHEMBL1685000 Bioactive AGN-PC-09QI2N
CFAMM00133637 CHEMBL1819563 Bioactive ethyl (3R)-1-[4-[4-chloro-N-(2,2-dimethylpropyl)-2-[(S)-hydroxy-(2-methoxyphenyl)methyl]-6-methoxyanilino]-4-oxobutanoyl]piperidine-3-carboxylate
CFAMM00133609 CHEMBL1819572 Bioactive ethyl (3S)-1-[4-[4-chloro-N-(2,2-dimethylpropyl)-2-ethoxy-6-[(S)-hydroxy-(2-methoxyphenyl)methyl]anilino]-4-oxobutanoyl]piperidine-3-carboxylate
CFAMM00133602 CHEMBL1819578 Bioactive (3S)-1-[4-[4-chloro-N-(2,2-dimethylpropyl)-2-[(S)-hydroxy-(2-methoxyphenyl)methyl]-6-(3-hydroxypropoxy)anilino]-4-oxobutanoyl]piperidine-3-carboxylic acid
CFAMM00133629 CHEMBL1684999 Bioactive AGN-PC-09QHSG
CFAMM00133608 CHEMBL1819573 Bioactive 1-[4-[4-chloro-N-(2,2-dimethylpropyl)-2-ethoxy-6-[(S)-hydroxy-(2-methoxyphenyl)methyl]anilino]-4-oxobutanoyl]piperidine-4-carboxylic acid
CFAMM00133621 CHEMBL1685017 Bioactive AGN-PC-09QKEI
CFAMM00133635 CHEMBL1819565 Bioactive 1-[4-[4-chloro-N-(2,2-dimethylpropyl)-2-[(S)-hydroxy-(2-methoxyphenyl)methyl]-6-methoxyanilino]-4-oxobutanoyl]piperidine-4-carboxylic acid
CFAMM00133601 CHEMBL1819579 Bioactive (3S)-1-[4-[4-chloro-N-(2,2-dimethylpropyl)-2-[(S)-hydroxy-(2-methoxyphenyl)methyl]-6-(3-hydroxy-3-methylbutoxy)anilino]-4-oxobutanoyl]piperidine-3-carboxylic acid
CFAMM00133614 CHEMBL1819581 Bioactive (3S)-1-[4-[4-chloro-N-(2,2-dimethylpropyl)-2-(3-hydroxy-2,2-dimethylpropoxy)-6-[(S)-hydroxy-(2-methoxyphenyl)methyl]anilino]-4-oxobutanoyl]piperidine-3-carboxylic acid
CFAMM00133581 DCL000147 Clinical Trial Drug Lapaquistat acetate

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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