CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFCD98
Family Name Leukotriene B4 receptor 1 Ligand Ltb 019 Family
No. of Seeds 3 No. of Other Members 35
Family Centroid CFAMM00133849 Functional Category Clinical Trial Drug
Superfamily Leukotriene B4 receptor 1 Ligand Ltb 019 Superfamily
Class Class 893

Cousin Family NamesSeedsMembers
Acetylcholinesterase Inhibitor Donepezil Family 23 242
Multidrug resistance protein Inhibitor Benzquinamide Family 1 41
Zucapsacin family 7 177
Endothelin-1 receptor Ligand Atrasentan Family 127 336
C-C chemokine receptor type 5 Ligand E-913 Family 6 44
5-hydroxytryptamine receptor 2A and D(2) dopamine receptor Lig... 3 89
cAMP-specific 3',5'-cyclic phosphodiesterase 4A and cAMP-speci... 2 16
Integrin beta-3 Inhibitor Lamifiban Family 3 4
Histamine H3 receptor Ligand A-349821 Family 49 228
Histamine H1 receptor Ligand MDL-105212 Family 16 56
Mitogen-activated protein kinase 14 Inhibitor N-(4-(trifluorom... 8 39
Melanin-concentrating hormone receptor 1 Ligand N-(1-benzylpip... 9 57
Neutrophil elastase Inhibitor N,n-bis(cyanomethyl)-3,4-dimetho... 3 30
Kappa-type opioid receptor Ligand 3-(1-benzylpiperidin-4-yloxy... 24 54
D(2) dopamine receptor Ligand Epidepride Family 31 66
Potassium voltage-gated channel subfamily KQT member 1 Ligand ... 5 17
Glycine receptor subunit beta Ligand ORG-25543 Family 10 153
Peptidyl-prolyl cis-trans isomerase FKBP1A inhibitor 2-[3-[(1R... 9 46
Pyruvate kinase PKM and Pyruvate kinase PKLR inhibitor MLS0022... 1 0
Prostaglandin E2 receptor EP3 subtype and Prostaglandin E2 rec... 55 36
Neutrophil elastase inhibitor (2S)-N-[(3S)-6-benzamido-5,5-dif... 6 10
Delta-type opioid receptor and Mu-type opioid receptor ligand ... 2 9
Prelamin-A/C and Nuclear receptor ROR-gamma ligand CHEMBL14038... 1 9
Matrix metalloproteinase-9 and Interstitial collagenase inhibi... 2 13
Prelamin-A/C and Beta-lactamase inhibitor CHEMBL1589265 family 1 0
Integrin beta-3 and Integrin alpha-IIb inhibitor (3R)-7-[(4-ca... 3 14
Collagenase 3 and 72 kDa type IV collagenase inhibitor N-[(3,4... 1 6
Kappa-type opioid receptor and Delta-type opioid receptor liga... 1 3
Cannabinoid receptor 1 ligand AGN-PC-03RV6L family 10 3
Histamine H3 receptor and Sodium-dependent serotonin transport... 2 11
Pol polyprotein inhibitor AC1LA3AI family 5 9
Integrin beta-3 and Integrin alpha-IIb inhibitor SureCN7680039... 4 4
Free fatty acid receptor 1 ligand (3R,4R)-3-[4-(3,4-dimethylph... 4 4
Muscarinic acetylcholine receptor M3 ligand N-[[3-[3-[(3-methy... 5 2
Cathepsin K inhibitor (2S)-2-[[2-(3,4-dimethoxyphenyl)acetyl]a... 1 1
Integrin beta-3 and Integrin alpha-IIb inhibitor AGN-PC-074LOQ... 3 0
Integrin beta-3 and Integrin alpha-IIb inhibitor 2-[6-[(4-carb... 1 0
Cannabinoid receptor 2 and Cannabinoid receptor 1 ligand N-[(4... 1 0
6,7-dihydropyrimido[6,1-a]isoquinolin-4-one NP ZINC02112138 Fa... 10 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00133866 CHEMBL89326 Bioactive Moxilubant [INN]
CFAMM00133849 DCL000155 Clinical Trial Drug LTB 019
CFAMM00133844 DNC004305 Investigative Drug Ro-43-8857

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

21767 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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