CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFHM1214
Family Name Lactones Metabolite (4S,6S)-3,4,5,6-Tetrahydro-4-hydroxy-6-methyl-2H-pyran-2-one Family
No. of Seeds 2 No. of Other Members 1
Family Centroid CFAMM00539822 Functional Category Human Metabolite
Superfamily Lactones Metabolite Mevalonolactone Superfamily
Class Class 7111

Cousin Family NamesSeedsMembers
Thyroid hormone receptor beta Ligand GC-1 Family 2 62
Melanocortin receptor 4 Ligand Melanocortin-4 Receptor Antagon... 1 56
Lymphocyte antigen 96 and Toll-like receptor 4 Ligand 3-hydrox... 1 56
Hydroxy Acids and Derivatives Metabolite (R)-3-Hydroxybutyric ... 5 10
Hydroxy Acids and Derivatives Metabolite 3-Hydroxyadipic acid ... 1 1
Hydroxy Acids and Derivatives Metabolite (R)-2,3-Dihydroxy-iso... 4 2
Hydroxy Acids and Derivatives Metabolite 3-Hydroxyisoheptanoic... 2 3
Hydroxy Acids and Derivatives Metabolite 3-Hydroxyvalproic aci... 2 4
Hydroxy Acids and Derivatives Metabolite 3-Hydroxy-2-methylglu... 1 4
Carboxylic Acids and Derivatives Metabolite 3-Hydroxyadipic ac... 2 1


External ID

Functional Category

Molecule Name

CFAMM00539822 HMDB33302 Human Metabolite (4S,6S)-3,4,5,6-Tetrahydro-4-hydroxy-6-methyl-2H-pyran-2-one
CFAMM00539820 HMDB39407 Human Metabolite Methyl (±)-3-hydroxyhexanoate

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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Computer-aided Drug Design
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