CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

Family Name Carboxylic Acids and Derivatives Metabolite Methylsuccinic acid Family
No. of Seeds 2 No. of Other Members 2
Family Centroid CFAMM00532761 Functional Category Human Metabolite
Superfamily Succinate-semialdehyde dehydrogenase, mitochondrial Inhibitor Succinic Acid Superfamily
Class Class 321

Cousin Family NamesSeedsMembers
Branched-chain-amino-acid aminotransferase, cytosolic Inhibito... 1 8
Fatty Acids and Conjugates Metabolite Butyric acid Family 1 1
Carboxylic Acids and Derivatives Metabolite Isobutyric acid Fa... 2 0
Fatty Acids and Conjugates Metabolite 2-Ethylbutanoic acid Family 1 0


External ID

Functional Category

Molecule Name

CFAMM00532759 HMDB02074 Human Metabolite 2,2-Dimethylsuccinic acid
CFAMM00532761 HMDB01844 Human Metabolite Methylsuccinic acid

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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