CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFHM2005
Family Name Naphthofurans Metabolite Pyrocurzerenone Family
No. of Seeds 1 No. of Other Members 9
Family Centroid CFAMM00544173 Functional Category Human Metabolite
Superfamily Naphthofurans Metabolite Pyrocurzerenone Superfamily
Class Class 98

Cousin Family NamesSeedsMembers
Retinoic acid receptor Ligand naphthoic acid derivative Adapal... 2 264
Cyclooxygenase Inhibitor Fenoprofen Family 4 1077
Prostaglandin G/H synthase 2 Inhibitor Nabumetone Family 4 267
Signal transducer and activator of transcription 3 Inhibitor A... 5 249
Vitamin K epoxide reductase complex subunit 1 Inhibitor Warfar... 9 508
DNA Binder Methoxsalen Family 10 1638
Vitamin K-dependent gamma-carboxylase Inhibitor Anisindione Fa... 3 243
Ipriflavone family 62 2480
Estrogen receptor beta Ligand 2-(4-hydroxy-phenyl)benzofuran-5... 5 82
Steryl-sulfatase Inhibitor Sulfamic Acid 4-(3-methoxy-benzoyl)... 5 24
cAMP-specific 3',5'-cyclic phosphodiesterase 4A Inhibitor 2,5-... 2 96
cAMP-specific 3',5'-cyclic phosphodiesterase 4A Inhibitor (2,5... 1 9
5-hydroxytryptamine receptor 1A and 5-hydroxytryptamine recept... 8 66
Aromatase and DNA-dependent protein kinase catalytic subunit I... 6 19
Oestrogen receptor and Estrogen receptor beta Ligand 7-chloro-... 2 27
Phospholipase A2 Inhibitor 3,9-dihydroxy-2,10-diprenylpterocap... 9 25
3-oxo-5-alpha-steroid 4-dehydrogenase 1 and 3-oxo-5-alpha-ster... 2 56
3-oxo-5-alpha-steroid 4-dehydrogenase 1 and 3-oxo-5-alpha-ster... 9 81
Oestrogen receptor and Estrogen receptor beta Ligand 3,8-dihyd... 20 57
Platelet-derived growth factor receptor beta Ligand Bis(5-meth... 5 220
Cytosolic phospholipase A2 Inhibitor [6,3''']biflavone Family 5 5
5-hydroxytryptamine receptor 2A and 5-hydroxytryptamine recept... 3 33
Cannabinoid receptor 1 and Cannabinoid receptor 2 Ligand 3-ben... 4 74
Cannabinoid receptor 2 Ligand 2-(2-methoxybenzyl)-3h-benzo[f]c... 6 32
Bifunctional epoxide hydrolase 2 Inhibitor 13-(5-n-pentylfuran... 1 80
NAD(P)H dehydrogenase [quinone] 1 Inhibitor 4-hydroxy-3-(2-nap... 12 1
Amine oxidase [flavin-containing] B Inhibitor 3-(4-methoxyphen... 3 29
Arachidonate 5-lipoxygenase Inhibitor 4,5-dimethoxy-10h-anthra... 1 4
Gamma-aminobutyric acid receptor subunit alpha-1 Ligand 2-(3-c... 5 72
Fatty-acid amide hydrolase 1 Inhibitor Benzofuran-2-ylboronic ... 1 14
CGMP-dependent protein kinase Inhibitor Tenellone A Family 1 7
Phospholipase A2 Inhibitor Helenaquinone Family 2 5
ELAV-like protein 1 and Myosin light chain kinase, smooth musc... 1 32
Retinoic acid receptor RXR-alpha and Peroxisome proliferator-a... 3 17
Acetylcholinesterase inhibitor AGN-PC-003A5N family 3 9
Amine oxidase [flavin-containing] B inhibitor 5-(4,4,4-trifluo... 2 9
Estrogen receptor beta and Estrogen receptor ligand 4-[(7E)-7-... 1 1
Amine oxidase [flavin-containing] B and Amine oxidase [flavin-... 7 13
Peroxisome proliferator-activated receptor delta and Peroxisom... 2 2
Sterol 26-hydroxylase, mitochondrial and 1,25-dihydroxyvitamin... 1 2
Prostaglandin G/H synthase 2 and Prostaglandin G/H synthase 1 ... 2 7
Transient receptor potential M8 protein ligand 2-[1-diethoxyph... 1 0
Tyrosine-protein phosphatase non-receptor type 1 ligand SureCN... 2 9
Indoleamine 2,3-dioxygenase 1 inhibitor AGN-PC-04S2CP family 1 3
Arachidonate 5-lipoxygenase inhibitor AGN-PC-00OPWJ family 1 1
Prelamin-A/C and Inositol monophosphatase 1 inhibitor MLS00053... 1 1
Prenol Lipids Metabolite Viburtinal Family 1 2
Acenes Metabolite Lacinilene C Family 2 3
Prenol Lipids Metabolite Furanogermenone Family 2 2
Prenol Lipids Metabolite Ipomeamaronol Family 2 2
Benzofurans Metabolite (R)-Bitalin A Family 1 9
Putative NP ZINC31158464 Family 3 5
5,6-dihydro-4H-furo[2',3':3,4]cyclohepta[1,2-b][1]benzofuran N... 3 0
6-chloro-7-(2,4-dioxopentan-3-ylidene)-3-(4-methylbenzoyl)-4-o... 1 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00544178 HMDB59897 Human Metabolite Benzofuran, 4,7-dimethyl-

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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