CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

Family Name Keto-Acids and Derivatives Metabolite 4-Hydroxy-2-oxoglutaric acid Family
No. of Seeds 2 No. of Other Members 0
Family Centroid CFAMM00532882 Functional Category Human Metabolite
Superfamily ATP-citrate synthase Inhibitor (-)-hydroxycitrate Superfamily
Class Class 1379

Cousin Family NamesSeedsMembers
Bis(5'-adenosyl)-triphosphatase Inhibitor Fructose Family 3 45
ATP-citrate synthase Inhibitor (-)-hydroxycitrate Family 4 25
Hydroxy Acids and Derivatives Metabolite (R)-2,3-Dihydroxy-iso... 4 2
Carboxylic Acids and Derivatives Metabolite 3-Isopropylmalate ... 1 0


External ID

Functional Category

Molecule Name

CFAMM00532882 HMDB02070 Human Metabolite 4-Hydroxy-2-oxoglutaric acid
CFAMM00532881 HMDB60466 Human Metabolite D-4-Hydroxy-2-oxoglutarate

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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