CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

Family Name Amino Acids and Derivatives Metabolite 5-Hydroxy-N-formylkynurenine Family
No. of Seeds 3 No. of Other Members 3
Family Centroid CFAMM00533642 Functional Category Human Metabolite
Superfamily Amino Acids Metabolite Hydroxykynurenine and Quinolines Metabolite Zeanic acid Superfamily
Class Class 517

Cousin Family NamesSeedsMembers
Histamine H1 receptor Ligand Tranilast Family 5 125
CGMP-inhibited 3',5'-cyclic phosphodiesterase Inhibitor Cilost... 6 202
Oestrogen receptor and Estrogen receptor beta Ligand 2-(4-hydr... 10 17
High affinity nerve growth factor receptor and RAF proto-oncog... 3 29
Macrophage migration inhibitory factor Inhibitor 2-(4-hydroxys... 8 19
5-hydroxytryptamine receptor 1A and 5-hydroxytryptamine recept... 1 16
Matrix metalloproteinase-9 and 72 kDa type IV collagenase inhi... 5 3
Kinesin-like protein KIF11 inhibitor 2-benzyl-3-(4-hydroxyphen... 2 5
Amino Acids and Derivatives Metabolite Hydroxykynurenine Family 4 9
Amino Acids and Derivatives Metabolite Xanthurenic acid Family 2 0
Phenols and Derivatives Metabolite Methyl 2,3-dihydro-3,5-dihy... 1 1
NP 7-hydroxy-2,3-dihydropyrrolo[2,1-b]quinazolin-9(1h)-one Family 2 0


External ID

Functional Category

Molecule Name

CFAMM00533643 HMDB12819 Human Metabolite 5-Hydroxykynurenine
CFAMM00533642 HMDB04086 Human Metabolite 5-Hydroxy-N-formylkynurenine
CFAMM00533640 HMDB12948 Human Metabolite Formyl-5-hydroxykynurenamine

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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