CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

Family Name Hydroxy Acids and Derivatives Metabolite (R)-2,3-Dihydroxy-isovalerate Family
No. of Seeds 4 No. of Other Members 2
Family Centroid CFAMM00531121 Functional Category Human Metabolite
Superfamily Carboxylic Acids Metabolite Citramalic acid and Sugar Acids Metabolite A,b-Dihydroxyisobutyric acid Superfamily
Class Class 7107

Cousin Family NamesSeedsMembers
Bis(5'-adenosyl)-triphosphatase Inhibitor Fructose Family 3 45
Fatty Acids and Conjugates Metabolite D-Leucic acid Family 5 4
Hydroxy Acids and Derivatives Metabolite 3-Hydroxyadipic acid ... 1 1
Keto-Acids and Derivatives Metabolite 4-Hydroxy-2-oxoglutaric ... 2 0
Sugar Acids and Derivatives Metabolite A,b-Dihydroxyisobutyric... 1 1
Carboxylic Acids and Derivatives Metabolite 3-Isopropylmalate ... 1 0
Lactones Metabolite (4S,6S)-3,4,5,6-Tetrahydro-4-hydroxy-6-met... 2 1


External ID

Functional Category

Molecule Name

CFAMM00531121 HMDB12141 Human Metabolite (R)-2,3-Dihydroxy-isovalerate
CFAMM00531120 HMDB12140 Human Metabolite (R) 2,3-Dihydroxy-3-methylvalerate
CFAMM00531125 HMDB29576 Human Metabolite 2,3-Dihydroxy-2-methylbutanoic acid
CFAMM00531124 HMDB00421 Human Metabolite 2,3-Dihydroxyvaleric acid

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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Computer-aided Drug Design
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