CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

Family Name Carboxylic Acids and Derivatives Metabolite 3-Isopropylmalate Family
No. of Seeds 1 No. of Other Members 0
Family Centroid CFAMM00534986 Functional Category Human Metabolite
Superfamily Aconitate hydratase, mitochondrial Inhibitor Alpha-methylisocitric Acid Superfamily
Class Class 1923

Cousin Family NamesSeedsMembers
ATP-citrate synthase Inhibitor (-)-hydroxycitrate Family 4 25
Aconitate hydratase, mitochondrial Inhibitor Alpha-methylisoci... 1 1
Fatty Acids and Conjugates Metabolite D-Leucic acid Family 5 4
Hydroxy Acids and Derivatives Metabolite (R)-2,3-Dihydroxy-iso... 4 2
Keto-Acids and Derivatives Metabolite 4-Hydroxy-2-oxoglutaric ... 2 0
Carboxylic Acids and Derivatives Metabolite Oxalosuccinic acid... 2 3


External ID

Functional Category

Molecule Name

CFAMM00534986 HMDB12156 Human Metabolite 3-Isopropylmalate

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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