CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFHM682
Family Name Benzyloxycarbonyls Metabolite Benzyl acetate Family
No. of Seeds 5 No. of Other Members 53
Family Centroid CFAMM00536632 Functional Category Human Metabolite
Superfamily Cathepsin B Inhibitor 3-amino-4-oxybenzyl-2-butanone Superfamily
Class Class 1807

Cousin Family NamesSeedsMembers
Antithrombin-III Inhibitor Heparin Family 2 74
Histamine H1 receptor Ligand Diphenhydramine Family 5 75
Kawain family 1 29
Benzyl Alcohol family 1 73
DNA topoisomerase 1 Inhibitor Beta-lapachone Family 3 66
DNA topoisomerase 2-beta Inhibitor Howiinol A (ghm-10) Family 1 42
Carbonic anhydrase 2 Inhibitor 4-(hydroxymercury)benzoic Acid ... 7 97
Renin Inhibitor 3-phenyl-1,2-propandiol Family 2 43
Cathepsin B Inhibitor 3-amino-4-oxybenzyl-2-butanone Family 1 10
Nicotinate-nucleotide pyrophosphorylase [carboxylating] Inhibi... 2 119
Beta-lactamase Inhibitor 4-carboxyphenylboronic Acid Family 1 1
Carbonic anhydrase 2 and Carbonic anhydrase 9 Inhibitor Sulfam... 4 4
C-X-C chemokine receptor type 1 and C-X-C chemokine receptor t... 2 53
Liver carboxylesterase 1 Inhibitor 2,2-dimethoxy-1,2-diphenyl-... 1 16
Gamma-secretase subunit APH-1B and Presenilin-1 Inhibitor (5r,... 3 9
Neutrophil elastase Inhibitor 3,4-dichloroisocoumarin Family 1 5
Protein kinase C delta type and Protein kinase C alpha type In... 4 105
4-hydroxyphenylpyruvate dioxygenase Inhibitor 3-hydroxy-4-phen... 1 8
Solute carrier family 52, riboflavin transporter, member 2 Inh... 1 7
Glutamate receptor ionotropic, NMDA 2A and Glutamate receptor ... 1 24
Fatty-acid amide hydrolase 1 Inhibitor 3-(ethoxycarbonyl)pheny... 2 69
Carbonic anhydrase 12 and Carbonic anhydrase 9 inhibitor Potas... 1 30
Arachidonate 15-lipoxygenase inhibitor SureCN9469035 family 6 40
Steroidogenic factor 1 and Nuclear receptor subfamily 5 group ... 2 14
Squalene synthase inhibitor [[4-[(1E)-2,6-dimethylhepta-1,5-di... 1 4
Arachidonate 15-lipoxygenase and Nuclear receptor ROR-gamma li... 1 18
Sigma non-opioid intracellular receptor 1 ligand 3-[(2S,4R)-2-... 3 5
Toll-like receptor 4 ligand dimethyl 2-[(2-fluorophenyl)methyl... 4 11
Thromboxane A2 receptor ligand (Z)-7-[(4S,5R)-2,2-dimethyl-4-p... 2 9
Acenes Metabolite Naphthalene epoxide Family 3 49
Epoxides Metabolite Phenylmethylglycidic ester Family 2 17
Aromatic Homomonocyclic Compounds Metabolite Dimethylbenzyl ca... 2 11
Acetals Metabolite Acetal R Family 7 49
Cinnamic Acid Derivatives Metabolite Cinnamyl cinnamate Family 1 7
Carboxylic Acids and Derivatives Metabolite 2-Phenylethyl form... 3 2
Carboxylic Acids and Derivatives Metabolite 3-Acetoxy-3-methyl... 2 0
Acetals Metabolite 1-Benzyloxy-1-(2-methoxyethoxy)ethane Family 3 50
Cinnamic Acid Derivatives Metabolite Tetrahydrofurfuryl cinnam... 1 4
Phenylpropenes Metabolite alpha-Amylcinnamyl acetate Family 3 3
Phenylpropenes Metabolite alpha-Amylcinnamyl formate Family 1 1
Phenylpropenes Metabolite [2-(Dimethoxymethyl)-1-heptenyl]benz... 1 0
Dioxolanes Metabolite 4-Methyl-2-(1-phenylethyl)-1,3-dioxolane... 2 0
Cinnamic Acid Derivatives Metabolite alpha-Terpinyl cinnamate ... 1 4
Benzyloxycarbonyls Metabolite Benzyl acetoacetate Family 1 6
Toluenes Metabolite Tolualdehyde glyceryl acetal Family 3 5
3-methyl-1-oxo-4H-isochromene-3-carboxylate NP Methyl 3-methyl... 4 1
NP 3,3,5,5-tetramethyl-6-(phenylethynyl)dihydro-2h-pyran-2,4(3... 6 3
2-methyl-6-phenyl-5-prop-1-en-2-yloxane-2-carbonitrile NP ZINC... 8 11
methylbenzoate NP 7-oxocyclohepta-1,3,5-trien-1-yl 3-methylben... 2 1
4-benzylidene-6-phenyl-1,2,3,6,6a,7,8,9-octahydrobenzo[c]chrom... 4 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00536621 HMDB41473 Human Metabolite (3-Methylphenyl)methyl acetate
CFAMM00536635 HMDB37715 Human Metabolite 1-Phenylethyl formate
CFAMM00536627 HMDB30063 Human Metabolite Benzyl propionate
CFAMM00536632 HMDB31310 Human Metabolite Benzyl acetate
CFAMM00536618 HMDB31250 Human Metabolite Phenylmethyl 2-methylpropanoate

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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