CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFHM718
Family Name Amino Acids and Derivatives Metabolite Flazine Family
No. of Seeds 3 No. of Other Members 2
Family Centroid CFAMM00536830 Functional Category Human Metabolite
Superfamily Substance-K receptor and Neuromedin-K receptor Binder Superfamily
Class Class 656

Cousin Family NamesSeedsMembers
cGMP-specific 3',5'-cyclic phosphodiesterase inhibitor indole... 28 2712
5-hydroxytryptamine receptor 1A and Sodium-dependent serotonin... 12 197
von Willebrand factor Inhibitor Auryntricarboxylic Acid (ata) ... 12 81
AP endonuclease APE1 Inhibitor 5-fluoro-1h-indole-2-carboxylic... 2 61
Vascular endothelial growth factor receptor 1 Ligand Lycogarub... 6 292
DNA-dependent protein kinase catalytic subunit Inhibitor 8-(1h... 3 85
Inosine-5'-monophosphate dehydrogenase 2 Inhibitor 3-(furan-3-... 3 44
Platelet-derived growth factor receptor alpha and Platelet-der... 4 54
Platelet-derived growth factor receptor alpha and Platelet-der... 2 13
RAC-gamma serine/threonine-protein kinase Inhibitor A-443654 F... 67 59
Platelet-derived growth factor receptor beta and Receptor-type... 1 2
Adenosine receptor A1 and Adenosine receptor A2a Ligand SB-298... 53 320
Gamma-aminobutyric acid receptor subunit alpha-1 and Gamma-ami... 24 64
Histamine H3 receptor ligand AGN-PC-00BG7Z family 11 49
D(3) dopamine receptor and 5-hydroxytryptamine receptor 1A lig... 10 50
Glutamate receptor ionotropic, NMDA 2D and Glutamate receptor ... 2 21
D(3) dopamine receptor ligand N-[4-[4-(2,3-dichlorophenyl)pipe... 3 15
RAC-alpha serine/threonine-protein kinase inhibitor 5-[5-[(2S)... 14 2
Serine/threonine-protein kinase pim-2 and cGMP-dependent prote... 8 1
3-oxo-5-alpha-steroid 4-dehydrogenase 2 inhibitor 4-(benzyloxy... 1 10
D(2) dopamine receptor and 5-hydroxytryptamine receptor 1A lig... 1 0
Cathepsin K inhibitor N-[(2S)-4-methyl-1-[2-[4-(2-methylpropox... 4 0
RAC-alpha serine/threonine-protein kinase inhibitor Isoquinoli... 1 0
Melatonin receptor type 1B and Melatonin receptor type 1A liga... 3 9
cGMP-specific 3',5'-cyclic phosphodiesterase inhibitor CHEMBL4... 6 2
Bombesin receptor subtype-3 ligand 2-[[(E)-furan-2-ylmethylide... 2 4
Sodium-dependent serotonin transporter inhibitor SureCN5477150... 4 1
Prelamin-A/C and Beta-lactamase inhibitor CHEMBL1340977 family 1 5
Potassium-transporting ATPase alpha chain 1 and Potassium-tran... 1 3
Indoles Metabolite Mukeic acid Family 1 1
Putative NP ZINC20113225 Family 2 0
NP Ethyl 7-amino-5h-[1,3]dioxolo[4,5-f]indole-6-carboxylate Fa... 2 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00536832 HMDB41200 Human Metabolite Dehydroxymethylflazine
CFAMM00536831 HMDB30327 Human Metabolite Perlolyrine
CFAMM00536830 HMDB33459 Human Metabolite Flazine

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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