CFam Chemical Families Database
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Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFHM758
Family Name Benzopyrans Metabolite (-)-trans-3,4-Dihydro-4,8-dihydroxy-3-methyl-1H-2-benzopyran-1-one Family
No. of Seeds 1 No. of Other Members 0
Family Centroid CFAMM00537116 Functional Category Human Metabolite
Superfamily Protein farnesyltransferase subunit beta Inhibitor Cylindrol A Superfamily
Class Class 776

Cousin Family NamesSeedsMembers
Prostaglandin G/H synthase 1 Inhibitor Salicyclic Acid Family 3 39
Cyclooxygenase inhibitor salicylate derivative Aspirin family 3 234
Inosine-5'-monophosphate dehydrogenase 2 Inhibitor Mycophenola... 4 353
Heat shock protein 90, putative Inhibitor Cromoglicate Family 14 2827
D-alanyl-D-alanine carboxypeptidase Inhibitor B-lactams Family 59 1364
Aldehyde oxidase Inhibitor Isovanillin Family 6 429
Hidrosmin family 14 61
Ipriflavone family 62 2480
Rotenone family 16 107
Danthron family 11 141
taste receptor Ligand Cynarin Family 6 124
Agrimophol family 10 22
Leukotriene B4 receptor 1 Ligand LY293111 Family 24 79
Heat shock protein 90, putative Inhibitor Radicicol Family 3 42
Interleukin-1 beta Inhibitor Diacerein Family 3 77
Glucose-6-phosphate translocase Inhibitor Mumbaistatin Family 3 11
Protein kinase C alpha type and Protein kinase C beta type Inh... 7 1
Estrogen receptor beta Ligand 3,6-dihydroxy-2-(4-hydroxy-pheny... 2 23
Oestrogen receptor and Estrogen receptor beta Ligand 3,8-dihyd... 20 57
Carbonic anhydrase 1 and Carbonic anhydrase 2 Inhibitor Ellagi... 1 11
Tyrosine-protein phosphatase non-receptor type 1 Ligand Licoag... 9 32
Squalene monooxygenase Inhibitor Octyl_gallate Family 5 5
Aromatase Inhibitor 3,4-bis(3,4-dimethoxyphenyl)furan-2(5h)-on... 4 86
Epidermal growth factor receptor Ligand 3-(3-chloro-phenyl)-5,... 10 64
Protein farnesyltransferase subunit beta Inhibitor Cylindrol A... 3 43
Tyrosinase Inhibitor 3-(2,4-dihydroxyphenyl)-propionic Acid Et... 3 8
Prostaglandin G/H synthase 2 Inhibitor 3,4-dibenzyloxy-2'-hydr... 7 40
CGMP-dependent protein kinase Inhibitor Tenellone A Family 1 7
72 kDa type IV collagenase Inhibitor Lithospermic Acid Family 1 0
Liver carboxylesterase 1 Inhibitor 2-methoxy-3,4-methylenediox... 4 26
Endothelin-1 receptor ligand (2S)-2-(1,3-benzodioxol-5-yl)-4-m... 17 0
Protein kinase C beta type and Protein kinase C eta type inhib... 1 0
Cholinesterase inhibitor [(3R,3aR,6S,6aR)-6-(ethylcarbamoyloxy... 2 4
Acetylcholinesterase inhibitor 5,7-Dimethoxy-2-methyl-indan-1-... 1 0
Solute carrier organic anion transporter family member 1B1 and... 1 0
Sterol O-acyltransferase 1 and Sterol O-acyltransferase 2 inhi... 1 5
Aldehyde dehydrogenase, cytosolic 1 and Aldehyde dehydrogenase... 2 0
72 kDa type IV collagenase inhibitor [(2S,3S,4R)-4-(4,5-dihydr... 1 0
Prenol Lipids Metabolite 13-Hydroxydihydromelleolide Family 3 0
Benzofurans Metabolite 4-Hydroxyphthalide Family 1 1
Benzoic Acid and Derivatives Metabolite Methyl 3-(2,3-dihydrox... 1 3
5-chloro-4,6,8-trihydroxy-7-methoxy-3-methyl-3,4-dihydroisochr... 4 0
Putative NP ZINC12652697 Family 8 1


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00537116 HMDB30765 Human Metabolite (-)-trans-3,4-Dihydro-4,8-dihydroxy-3-methyl-1H-2-benzopyran-1-one

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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