CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFID1008
Family Name Ribosyldihydronicotinamide dehydrogenase [quinone] Inhibitor 5,8-dimethoxy-1,4-dimethylquinolin-2(1h)-one Family
No. of Seeds 4 No. of Other Members 24
Family Centroid CFAMM00224871 Functional Category Investigative Drug with Human Metabolite & Natural Product
Superfamily Ribosyldihydronicotinamide dehydrogenase [quinone] Binder Superfamily
Class Class 1929

Cousin Family NamesSeedsMembers
Dihydroorotate dehydrogenase and Interleukin-17A Inhibitor Vid... 4 74
5-hydroxytryptamine receptor 1A Ligand (s)-way 100135 Family 94 975
Cannabinoid receptor 1 Ligand N-(4-methoxyphenyl)oleamide Family 4 23
Macrophage migration inhibitory factor Inhibitor 3-benzyl-5-me... 10 42
Ribosyldihydronicotinamide dehydrogenase [quinone] Inhibitor 5... 4 1
Ribosyldihydronicotinamide dehydrogenase [quinone] Inhibitor 6... 1 1
Ribosyldihydronicotinamide dehydrogenase [quinone] Inhibitor 6... 2 0
5-hydroxytryptamine receptor 1A and 5-hydroxytryptamine recept... 2 9
Aldose reductase Inhibitor (6-hydroxy-2-oxo-2h-quinolin-1-yl)-... 3 4
Cannabinoid receptor 2 ligand 8-butoxy-N-(2-fluoro-2-phenyleth... 12 7
Cannabinoid receptor 2 ligand 8-butoxy-N-[2-(4-fluorophenyl)et... 1 0
Cannabinoid receptor 2 and Cannabinoid receptor 1 ligand N-[2-... 3 0
Cannabinoid receptor 2 ligand 8-butoxy-7-methoxy-2-oxo-1H-quin... 1 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00224837 DNC008794 Investigative Drug 5,8-Dimethoxy-4-methylquinolin-2(1H)-one
CFAMM00224835 DNC008801 Investigative Drug 8-Methoxy-1,4-dimethylquinolin-2(1H)-one
CFAMM00224871 DNC003349 Investigative Drug 5,8-dimethoxy-1,4-dimethylquinolin-2(1H)-one
CFAMM00224839 DNC008797 Investigative Drug 7,8-Dimethoxy-1,4-dimethylquinolin-2(1H)-one

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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