CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFID1028
Family Name Tyrosine-protein phosphatase non-receptor type 1 Ligand 2-(oxalyl-amino)-benzoic Acid Family
No. of Seeds 3 No. of Other Members 11
Family Centroid CFAMM00225586 Functional Category Investigative Drug with Natural Product
Superfamily Tyrosine-protein phosphatase non-receptor type 1 Ligand 2-(oxalyl-amino)-benzoic Acid Superfamily
Class Class 1940

Cousin Family NamesSeedsMembers
Sodium channel protein type 10 subunit alpha Ligand Tetracaine... 6 166
Retinoic acid receptor alpha Ligand Tamibarotene Family 5 95
Cyclooxygenase Inhibitor Diclofenac Family 6 37
Prostaglandin G/H synthase 1 Inhibitor Mesalazine Family 2 30
Prostaglandin G/H synthase 2 Inhibitor Mefenamic Acid Family 7 137
Cyclooxygenase Inhibitor Meclofenamic Acid Family 4 11
Serum albumin Inhibitor Iodipamide Family 2 23
Histamine H1 receptor Ligand Tranilast Family 5 125
New permeability pathways Inhibitor 5-nitro-2-(3-phenylpropyla... 1 13
Glycogen synthase kinase-3 beta Inhibitor I-5 Family 1 8
Neuraminidase Inhibitor 4-(acetylamino)-3-amino Benzoic Acid F... 2 27
High affinity nerve growth factor receptor and RAF proto-oncog... 3 29
Dihydroorotate dehydrogenase Inhibitor 2-(2-bromo-2-naphthamid... 1 2
3-oxo-5-alpha-steroid 4-dehydrogenase 2 Inhibitor 4-[4-(benzyl... 2 19
Fatty acid synthase Inhibitor 4-hydroxy-6-nitro-3-phenylquinol... 2 2
Glutamate receptor ionotropic, kainate 1 Ligand 2-(3-(3-bromop... 2 1
Bifunctional epoxide hydrolase 2 Inhibitor 4-(3-adamantan-1-yl... 3 12
Acetylcholinesterase Inhibitor 3-(2,5-dioxo-pyrrolidin-1-yl)-b... 2 4
Glutamate receptor ionotropic, NMDA 2A and Glutamate receptor ... 3 8
Glutamate receptor ionotropic, NMDA 2A and Glutamate receptor ... 1 3
Glutamate receptor ionotropic, NMDA 2A and Glutamate receptor ... 6 13
Tubulin beta chain Inhibitor Gnf-pf-117 Family 2 16
Integrin beta-3 and Integrin alpha-IIb inhibitor 2-[7-[[4-(N'-... 7 15
Prostaglandin E2 receptor EP4 subtype ligand SureCN3567929 family 10 3
Prostaglandin E synthase inhibitor 2-[(2Z)-2-[3-methyl-1-(4-ni... 1 0
Hydroxycarboxylic acid receptor 2 and Cytochrome P450 2C8 liga... 2 0
Caspase-9 and Caspase-8 inhibitor 4-fluoro-2-[[2-[[(2S)-3-meth... 1 11
Integrin beta-3 and Integrin alpha-V inhibitor SureCN7494201 f... 5 14
Retinoic acid receptor beta and Retinoic acid receptor gamma l... 4 7
Carbonic anhydrase 9 and Carbonic anhydrase 2 inhibitor AGN-PC... 2 1
DNA-(apurinic or apyrimidinic site) lyase and ATP-dependent DN... 1 8
Glycogen synthase kinase-3 beta and Glycogen synthase kinase-3... 1 1
Cannabinoid receptor 2 and Cannabinoid receptor 1 ligand 4-[[1... 2 5
Aldo-keto reductase family 1 member C3 and Aldo-keto reductase... 1 0
Tankyrase-2 inhibitor 3-chloro-4-(4-methyl-2-oxo-1H-quinolin-7... 1 2
Cytochrome P450 2C19 and 3-hydroxyacyl-CoA dehydrogenase type-... 1 5
Aldo-keto reductase family 1 member C3 and Aldo-keto reductase... 1 2
Aldo-keto reductase family 1 member C3 and Aldo-keto reductase... 1 0
Falcipain 2 and Cysteine protease falcipain-3 inhibitor STK367... 1 0
Glucocorticoid receptor ligand AGN-PC-01X8JJ family 1 0
Holo-[acyl-carrier-protein] synthase inhibitor AGN-PC-00CGZN f... 1 0
Prenol Lipids Metabolite alpha-Terpinyl anthranilate Family 1 4
NP Methyl 3-acetyl-4-oxo-1,4-dihydroquinoline-8-carboxylate Fa... 2 0
2-oxo-1H-quinoline-4-carboxylate NP ZINC19735150 Family 5 4
Putative NP ZINC04061910 Family 6 3
Putative NP ZINC00192342 Family 2 1
Putative NP ZINC04043929 Family 4 1


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00225587 DNC003396 Investigative Drug Novo Nordisk a/S Compound
CFAMM00225586 DNC003395 Investigative Drug 2-(Oxalyl-Amino)-Benzoic Acid

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

27254 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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