CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFID1077
Family Name Glutamate receptor ionotropic, NMDA 2A and Glutamate receptor ionotropic, NMDA 2B Ligand Tenocyclidine Family
No. of Seeds 2 No. of Other Members 39
Family Centroid CFAMM00227036 Functional Category Investigative Drug
Superfamily Mu-type opioid receptor and Delta-type opioid receptor Binder Superfamily 2
Class Class 1925

Cousin Family NamesSeedsMembers
Histamine H1 receptor ligand piperazine derivative Cyclizine F... 16 140
Muscarinic acetylcholine receptor M5 Ligand Metixene Family 5 24
Leukotriene A-4 hydrolase Inhibitor N-methyl-1-(2-thiophen-2-y... 2 28
5-hydroxytryptamine receptor 5A and 5-hydroxytryptamine recept... 12 20
Potassium voltage-gated channel subfamily H member 2 Ligand 4-... 4 26
Sodium-dependent dopamine transporter Inhibitor 1-(1-benzo[b]t... 5 5
Sodium-dependent dopamine transporter and Sodium-dependent nor... 28 71
Sodium-dependent dopamine transporter Inhibitor 1-benzo[b]thio... 3 0
Sodium-dependent serotonin transporter and Sodium-dependent no... 12 0
Sodium-dependent dopamine transporter inhibitor 1-[1-(1-benzot... 1 1
5-hydroxytryptamine receptor 1A ligand (2R)-N,N-dipropyl-8-thi... 2 4
Alpha-1A adrenergic receptor and Alpha-2A adrenergic receptor ... 2 8
Survival motor neuron protein and Inositol monophosphatase 1 i... 1 4
Muscarinic acetylcholine receptor M3 and Muscarinic acetylchol... 2 0
Sigma non-opioid intracellular receptor 1 and 3-beta-hydroxyst... 4 12
Muscarinic acetylcholine receptor M2 and Muscarinic acetylchol... 2 2
5-hydroxytryptamine receptor 2A and Muscarinic acetylcholine r... 1 2
Sodium-dependent dopamine transporter and Sodium-dependent nor... 1 0
Protein kinase C theta type and Protein kinase C delta type in... 1 0
Muscarinic acetylcholine receptor M2 and Muscarinic acetylchol... 1 1
C-X-C chemokine receptor type 3 ligand [(1S,5R)-6,6-dimethyl-4... 1 1


External ID

Functional Category

Molecule Name

CFAMM00227033 CHEMBL1743767 Bioactive (4S,9aS)-4-phenyl-4,5,7,8,9,9a-hexahydrothieno[2,3-g]indolizine;hydrobromide
CFAMM00227036 DNC003501 Investigative Drug Tenocyclidine

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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